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Accurately assessing a patient's risk of a given event is essential in making informed treatment decisions. One approach is to stratify patients into two or more distinct risk groups with respect to a specific outcome using both clinical…

Methodology · Statistics 2015-03-17 Karen Lostritto , Robert Strawderman , Annette Molinaro

Lung cancer remains one of the most common and deadliest forms of cancer worldwide. The likelihood of successful treatment depends strongly on the stage at which the disease is diagnosed. Therefore, early detection of lung cancer represents…

Image and Video Processing · Electrical Eng. & Systems 2026-02-16 Volodymyr Sydorskyi

Breast cancer, the second leading cause of cancer-related deaths globally, accounts for a quarter of all cancer cases [1]. To lower this death rate, it is crucial to detect tumors early, as early-stage detection significantly improves…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Samia Saeed , Khuram Naveed

Lung cancer is the leading cause of cancer-related mortality in adults worldwide. Screening high-risk individuals with annual low-dose CT (LDCT) can support earlier detection and reduce deaths, but widespread implementation may strain the…

Machine Learning · Computer Science 2025-12-30 Shaurya Gaur , Michel Vitale , Alessa Hering , Johan Kwisthout , Colin Jacobs , Lena Philipp , Fennie van der Graaf

Colorectal cancer is one of fatal cancer worldwide. Colonoscopy is the standard treatment for examination, localization, and removal of colorectal polyps. However, it has been shown that the miss-rate of colorectal polyps during colonoscopy…

Image and Video Processing · Electrical Eng. & Systems 2021-01-12 Nikhil Kumar Tomar

Dealing with the application of grading colorectal cancer images, this work proposes a 3 step pipeline for prediction of cancer levels from a histopathology image. The overall model performs better compared to other state of the art methods…

Computer Vision and Pattern Recognition · Computer Science 2020-10-05 Franziska Lippoldt

Colorectal cancer liver metastases (CLM) are the most common type of distant metastases originating from the abdomen and are characterized by a high recurrence rate after curative resection. It has been previously reported that CLM…

Quantitative Methods · Quantitative Biology 2023-03-09 Ralph Saber , David Henault , Rolando Rebolledo , Simon Turcotte , Samuel Kadoury

Gastric cancer is the second leading cause of cancer-related deaths worldwide, and the major hurdle in biomedical image analysis is the determination of the cancer extent. This assignment has high clinical relevance and would generally…

Computer Vision and Pattern Recognition · Computer Science 2017-12-21 Yang Nan , Gianmarc Coppola , Qiaokang Liang , Kunglin Zou , Wei Sun , Dan Zhang , Yaonan Wang , Guanzhen Yu

Early screening for cancer has proven to improve the survival rate and spare patients from intensive and costly treatments due to late diagnosis. Cancer screening in the healthy population involves an initial risk stratification step to…

Lung cancer is the leading cause of cancer-related mortality worldwide. Lung cancer screening (LCS) using annual low-dose computed tomography (CT) scanning has been proven to significantly reduce lung cancer mortality by detecting cancerous…

Randomized Controlled Trials (RCTs) are the gold standard for comparing the effectiveness of a new treatment to the current one (the control). Most RCTs allocate the patients to the treatment group and the control group by uniform…

Machine Learning · Statistics 2018-10-22 Onur Atan , William R. Zame , Mihaela van der Schaar

Colorectal cancer (CRC) is highly heterogeneous, with five-year survival rates dropping from $\sim$90% in localized disease to $\sim$15% with distant metastases. Disease progression is shaped not only by tumor-intrinsic alterations but also…

Breast cancer is a prevalent form of cancer among women, with over 1.5 million women being diagnosed each year. Unfortunately, the survival rates for breast cancer patients in certain third-world countries, like South Africa, are alarmingly…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Brennon Maistry , Absalom E. Ezugwu

Oral cancer incidence is rapidly increasing worldwide. The most important determinant factor in cancer survival is early diagnosis. To facilitate large scale screening, we propose a fully automated pipeline for oral cancer detection on…

Image and Video Processing · Electrical Eng. & Systems 2020-09-14 Jiahao Lu , Nataša Sladoje , Christina Runow Stark , Eva Darai Ramqvist , Jan-Michaél Hirsch , Joakim Lindblad

Definition of the clinical target volume (CTV) is one of the weakest links in the radiation therapy chain. In particular, inability to account for uncertainties is a severe limitation in the traditional CTV delineation approach. Here, we…

Medical Physics · Physics 2018-08-15 Nadya Shusharina , David Craft , Yen-Lin Chen , Helen Shih , Thomas Bortfeld

Colorectal cancer is one of the most common cancers worldwide, so early pathological examination is very important. However, it is time-consuming and labor-intensive to identify the number and type of cells on H&E images in clinical.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-17 Chia-Yen Lee , Hsiang-Chin Chien , Ching-Ping Wang , Hong Yen , Kai-Wen Zhen , Hong-Kun Lin

In this work, we investigate the importance of ethnicity in colorectal cancer survivability prediction using machine learning techniques and the SEER cancer incidence database. We compare model performances for 2-year survivability…

Machine Learning · Computer Science 2019-01-15 Samuel Li , Talayeh Razzaghi

A large number of different lesions and pathologies can affect the human digestive system, resulting in life-threatening situations. Early detection plays a relevant role in the successful treatment and the increase of current survival…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Adrian Galdran , Gustavo Carneiro , Miguel A. González Ballester

Colorectal cancer (CRC), which frequently originates from initially benign polyps, remains a significant contributor to global cancer-related mortality. Early and accurate detection of these polyps via colonoscopy is crucial for CRC…

Computer Vision and Pattern Recognition · Computer Science 2024-04-18 Ziyu Zhou , Wenyuan Shen , Chang Liu