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Lung cancer is the leading cause of cancer death worldwide, with lung adenocarcinoma being the most prevalent form of lung cancer. EGFR positive lung adenocarcinomas have been shown to have high response rates to TKI therapy, underlying the…
Cardiotoxicity induced by cancer treatment has become a major clinical concern, affecting the long-term survival and quality of life of cancer patients. Effective clinical decision-making, including the detection of cancer treatment-induced…
Lung cancer is the leading cause of cancer related mortality by a significant margin. While new technologies, such as image segmentation, have been paramount to improved detection and earlier diagnoses, there are still significant…
Skin cancer is the most common type of cancer. Specifically, melanoma is the cause of 75% of skin cancer deaths, although it is the least common skin cancer. Better detection of melanoma could have a positive impact on millions of people.…
Cancer is one of the most life-threatening diseases worldwide, and head and neck (H&N) cancer is a prevalent type with hundreds of thousands of new cases recorded each year. Clinicians use medical imaging modalities such as computed…
Colorectal cancer is the most common cancer in Singapore and the third most common cancer worldwide. Blood in a person's stool is a symptom of this disease, and it is usually detected by the faecal occult blood test (FOBT). However, the…
Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide and the leading cause of cancer-related deaths in adults under 55, involving a complex interplay of biological processes such as dendritic cell (DC) maturation…
Recurrent events, characterized by the repeated occurrence of the same event in an individual, are a common type of data in medical research. Motivated by cancer recurrences, we aim to estimate the optimal individualized treatment regime…
Lung cancer is one of the death threatening diseases among human beings. Early and accurate detection of lung cancer can increase the survival rate from lung cancer. Computed Tomography (CT) images are commonly used for detecting the lung…
Uncertainty quantification is necessary for developers, physicians, and regulatory agencies to build trust in machine learning predictors and improve patient care. Beyond measuring uncertainty, it is crucial to express it in clinically…
Quantitative tools are increasingly appealing for decision support in healthcare, driven by the growing capabilities of advanced AI systems. However, understanding the predictive uncertainties surrounding a tool's output is crucial for…
Organ and cancer segmentation in abdomen Computed Tomography (CT) scans is the prerequisite for precise cancer diagnosis and treatment. Most existing benchmarks and algorithms are tailored to specific cancer types, limiting their ability to…
Liver tumor segmentation and classification are important tasks in computer aided diagnosis. We aim to address three problems: liver tumor screening and preliminary diagnosis in non-contrast computed tomography (CT), and differential…
Colorectal cancer is a prevalent form of cancer, and many patients develop colorectal cancer liver metastasis (CRLM) as a result. Early detection of CRLM is critical for improving survival rates. Radiologists usually rely on a series of…
Pancreatic cancer (PC) is the fourth leading cause of cancer death in the United States due to its five-year survival rate of 10%. Late diagnosis, affiliated with the asymptomatic nature in early stages and the location of the cancer with…
Head and neck cancers are the fifth most common cancer worldwide, and recently, analysis of Positron Emission Tomography (PET) and Computed Tomography (CT) images has been proposed to identify patients with a prognosis. Even though the…
Background and Purpose: Colorectal cancer is a common fatal malignancy, the fourth most common cancer in men, and the third most common cancer in women worldwide. Timely detection of cancer in its early stages is essential for treating the…
When delineating lesions from medical images, a human expert can always keep in mind the anatomical structure behind the voxels. However, although high-quality (though not perfect) anatomical information can be retrieved from computed…
The treatment of cancer is one of the most discussed issues in the realm of contemporary public health research. One of the primary concerns of both the general public and the government is the development of the most effective cancer…
Renal cell carcinoma represents a significant global health challenge with a low survival rate. This research aimed to devise a comprehensive deep-learning model capable of predicting survival probabilities in patients with renal cell…