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Recovery after stroke is often incomplete, but rehabilitation training may potentiate recovery by engaging endogenous neuroplasticity. In preclinical models of stroke, high doses of rehabilitation training are required to restore functional…

Signal Processing · Electrical Eng. & Systems 2020-06-22 Aakash Kaku , Avinash Parnandi , Anita Venkatesan , Natasha Pandit , Heidi Schambra , Carlos Fernandez-Granda

Establishing causality is a fundamental goal in fields like medicine and social sciences. While randomized controlled trials are the gold standard for causal inference, they are not always feasible or ethical. Observational studies can…

Statistics Theory · Mathematics 2024-12-03 Andrew Ying

Clinical outcome prediction plays an important role in stroke patient management. From a machine learning point-of-view, one of the main challenges is dealing with heterogeneous data at patient admission, i.e. the image data which are…

Image and Video Processing · Electrical Eng. & Systems 2022-05-12 Nima Hatami , Tae-Hee Cho , Laura Mechtouff , Omer Faruk Eker , David Rousseau , Carole Frindel

Stroke remains a significant global health concern, necessitating precise and efficient diagnostic tools for timely intervention and improved patient outcomes. The emergence of deep learning methodologies has transformed the landscape of…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Yalda Zafari-Ghadim , Essam A. Rashed , Mohamed Mabrok

We present a deep transformation model for probabilistic regression. Deep learning is known for outstandingly accurate predictions on complex data but in regression tasks, it is predominantly used to just predict a single number. This…

Machine Learning · Statistics 2020-04-02 Beate Sick , Torsten Hothorn , Oliver Dürr

Deep structured models are widely used for tasks like semantic segmentation, where explicit correlations between variables provide important prior information which generally helps to reduce the data needs of deep nets. However, current…

Machine Learning · Computer Science 2018-11-02 Colin Graber , Ofer Meshi , Alexander Schwing

The preservation of the corticospinal tract (CST) is key to good motor recovery after stroke. The gold standard method of assessing the CST with imaging is diffusion tensor tractography. However, this is not available for most intracerebral…

Stroke is a major cause of death and disability worldwide. Accurate outcome and evolution prediction has the potential to revolutionize stroke care by individualizing clinical decision-making leading to better outcomes. However, despite a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Adam Marcus , Paul Bentley , Daniel Rueckert

Mechanical thrombectomy has become the standard of care in patients with stroke due to large vessel occlusion (LVO). However, only 50% of successfully treated patients show a favorable outcome. We developed and evaluated interpretable deep…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Lisa Herzog , Pascal Bühler , Ezequiel de la Rosa , Beate Sick , Susanne Wegener

This study proposes a multi-modal fusion framework Multitrans based on the Transformer architecture and self-attention mechanism. This architecture combines the study of non-contrast computed tomography (NCCT) images and discharge diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Danqing Ma , Meng Wang , Ao Xiang , Zongqing Qi , Qin Yang

Predicting stroke risk is a complex challenge that can be enhanced by integrating diverse clinically available data modalities. This study introduces a self-supervised multimodal framework that combines 3D brain imaging, clinical data, and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Camille Delgrange , Olga Demler , Samia Mora , Bjoern Menze , Ezequiel de la Rosa , Neda Davoudi

Image-to-Image translation models can help mitigate various challenges inherent to medical image acquisition. Latent diffusion models (LDMs) leverage efficient learning in compressed latent space and constitute the core of state-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Junhyeok Lee , Hyunwoong Kim , Hyungjin Chung , Heeseong Eom , Joon Jang , Chul-Ho Sohn , Kyu Sung Choi

Deep learning (DL) methods have in recent years yielded impressive results in medical imaging, with the potential to function as clinical aid to radiologists. However, DL models in medical imaging are often trained on public research…

Stroke is a major public health problem, affecting millions worldwide. Deep learning has recently demonstrated promise for enhancing the diagnosis and risk prediction of stroke. However, existing methods rely on costly medical imaging…

Image and Video Processing · Electrical Eng. & Systems 2025-12-17 Saeed Shurrab , Aadim Nepal , Terrence J. Lee-St. John , Nicola G. Ghazi , Bartlomiej Piechowski-Jozwiak , Farah E. Shamout

Recent deep learning research based on Transformer model architectures has demonstrated state-of-the-art performance across a variety of domains and tasks, mostly within the computer vision and natural language processing domains. While…

Machine Learning · Computer Science 2021-11-11 Benjamin Shickel , Patrick J. Tighe , Azra Bihorac , Parisa Rashidi

Deep neural networks (DNNs) have shown exceptional performances in a wide range of tasks and have become the go-to method for problems requiring high-level predictive power. There has been extensive research on how DNNs arrive at their…

Machine Learning · Computer Science 2023-02-21 Mattias Luber , Anton Thielmann , Benjamin Säfken

In this paper we describe the implementation of semi-structured deep distributional regression, a flexible framework to learn conditional distributions based on the combination of additive regression models and deep networks. Our…

Research in many fields has shown that transfer learning (TL) is well-suited to improve the performance of deep learning (DL) models in datasets with small numbers of samples. This empirical success has triggered interest in the application…

Neurons and Cognition · Quantitative Biology 2021-11-03 Armin W. Thomas , Ulman Lindenberger , Wojciech Samek , Klaus-Robert Müller

The differential diagnosis of neurodegenerative dementias is a challenging clinical task, mainly because of the overlap in symptom presentation and the similarity of patterns observed in structural neuroimaging. To improve diagnostic…

Machine Learning · Computer Science 2025-05-27 Andrew Zamai , Nathanael Fijalkow , Boris Mansencal , Laurent Simon , Eloi Navet , Pierrick Coupe

In this paper, we demonstrate the feasibility and performance of deep residual neural networks for volumetric segmentation of irreversibly damaged brain tissue lesions on T1-weighted MRI scans for chronic stroke patients. A total of 239…

Image and Video Processing · Electrical Eng. & Systems 2019-11-27 Naofumi Tomita , Steven Jiang , Matthew E. Maeder , Saeed Hassanpour