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Aim: This study aims to enhance interpretability and explainability of multi-modal prediction models integrating imaging and tabular patient data. Methods: We adapt the xAI methods Grad-CAM and Occlusion to multi-modal, partly interpretable…

Image and Video Processing · Electrical Eng. & Systems 2025-04-10 Jonas Brändli , Maurice Schneeberger , Lisa Herzog , Loran Avci , Nordin Dari , Martin Häansel , Hakim Baazaoui , Pascal Bühler , Susanne Wegener , Beate Sick

Outcomes with a natural order commonly occur in prediction tasks and often the available input data are a mixture of complex data like images and tabular predictors. Deep Learning (DL) models are state-of-the-art for image classification…

Machine Learning · Statistics 2021-04-21 Lucas Kook , Lisa Herzog , Torsten Hothorn , Oliver Dürr , Beate Sick

An every increasing number of clinical trials features a time-to-event outcome and records non-tabular patient data, such as magnetic resonance imaging or text data in the form of electronic health records. Recently, several neural-network…

Machine Learning · Computer Science 2022-10-24 Gabriele Campanella , Lucas Kook , Ida Häggström , Torsten Hothorn , Thomas J. Fuchs

Recent randomised clinical trials have shown that patients with ischaemic stroke {due to occlusion of a large intracranial blood vessel} benefit from endovascular thrombectomy. However, predicting outcome of treatment in an individual…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Zeynel A. Samak , Philip Clatworthy , Majid Mirmehdi

Accurate prediction of functional outcomes after acute ischemic stroke can inform clinical decision-making and resource allocation. Prior work on modified Rankin Scale (mRS) prediction has relied primarily on structured variables (e.g.,…

Machine learning offers great potential for automated prediction of post-stroke symptoms and their response to rehabilitation. Major challenges for this endeavour include the very high dimensionality of neuroimaging data, the relatively…

Artificial Intelligence · Computer Science 2023-10-31 Adam White , Margarita Saranti , Artur d'Avila Garcez , Thomas M. H. Hope , Cathy J. Price , Howard Bowman

Stroke is a major global health problem that causes mortality and morbidity. Predicting the outcomes of stroke intervention can facilitate clinical decision-making and improve patient care. Engaging and developing deep learning techniques…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Zeynel A. Samak , Philip Clatworthy , Majid Mirmehdi

Stroke is a common disabling neurological condition that affects about one-quarter of the adult population over age 25; more than half of patients still have poor outcomes, such as permanent functional dependence or even death, after the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-19 Chia-Ling Tsai , Hui-Yun Su , Shen-Feng Sung , Wei-Yang Lin , Ying-Ying Su , Tzu-Hsien Yang , Man-Lin Mai

Treatment of acute ischemic strokes (AIS) is largely contingent upon the time since stroke onset (TSS). However, TSS may not be readily available in up to 25% of patients with unwitnessed AIS. Current clinical guidelines for patients with…

Image and Video Processing · Electrical Eng. & Systems 2021-05-03 Haoyue Zhang , Jennifer S Polson , Kambiz Nael , Noriko Salamon , Bryan Yoo , Suzie El-Saden , Fabien Scalzo , William Speier , Corey W Arnold

Accurate prediction of postoperative complications can inform shared decisions regarding prognosis, preoperative risk-reduction, and postoperative resource use. We hypothesized that multi-task deep learning models would outperform random…

Postoperative complications pose a significant challenge in the healthcare industry, resulting in elevated healthcare expenses and prolonged hospital stays, and in rare instances, patient mortality. To improve patient outcomes and reduce…

Machine Learning · Computer Science 2023-06-07 Reza Shirkavand , Fei Zhang , Heng Huang

Deep learning and multi-modal fusion have demonstrated transformative potential in medical diagnosis by integrating diverse data sources. However, accurate prognosis for ischemic stroke remains challenging due to limitations in existing…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Liren Chen , Lidong Sun , Mingyan Huang , Junzhe Tang , Yinghui Zhu , Guanjie Wang , Yiqing Xia , Ting Xiao

Purpose: To develop a data-efficient strategy for accelerated MRI reconstruction with Diffusion Probabilistic Generative Models (DPMs) that enables faster scan times in clinical stroke MRI when only limited fully-sampled data samples are…

Image and Video Processing · Electrical Eng. & Systems 2026-03-16 Yamin Arefeen , Sidharth Kumar , Steven Warach , Hamidreza Saber , Jonathan Tamir

Brain stroke remains one of the principal causes of death and disability worldwide, yet most tabular-data prediction models still hover below the 95% accuracy threshold, limiting real-world utility. Addressing this gap, the present work…

Quantitative Methods · Quantitative Biology 2026-05-22 Yousuf Islam , Md. Jalal Uddin Chowdhury , Sumon Chandra Das

Stroke is the second most common cause of death in developed countries, where rapid clinical intervention can have a major impact on a patient's life. To perform the revascularization procedure, the decision making of physicians considers…

Computer Vision and Pattern Recognition · Computer Science 2018-09-25 Adriano Pinto , Sergio Pereira , Raphael Meier , Victor Alves , Roland Wiest , Carlos A. Silva , Mauricio Reyes

Deep learning based disease detection and segmentation algorithms promise to improve many clinical processes. However, such algorithms require vast amounts of annotated training data, which are typically not available in the medical context…

Image and Video Processing · Electrical Eng. & Systems 2021-11-02 Moritz Platscher , Jonathan Zopes , Christian Federau

Stroke is a major cause of mortality and long--term disability in the world. Predictive outcome models in stroke are valuable for personalized treatment, rehabilitation planning and in controlled clinical trials. In this paper we design a…

Applications · Statistics 2016-02-24 Abhishek Sengupta , Vaibhav Rajan , Sakyajit Bhattacharya , G R K Sarma

Despite the impressive advancements achieved using deep-learning for functional brain activity analysis, the heterogeneity of functional patterns and scarcity of imaging data still pose challenges in tasks such as prediction of future onset…

Image and Video Processing · Electrical Eng. & Systems 2023-12-25 Wenhui Cui , Haleh Akrami , Ganning Zhao , Anand A. Joshi , Richard M. Leahy

The ability to interpret machine learning model decisions is critical in such domains as healthcare, where trust in model predictions is as important as their accuracy. Inspired by the development of prototype parts-based deep neural…

Machine Learning · Computer Science 2026-03-06 Jacek Karolczak , Jerzy Stefanowski

Objective: Post-traumatic epilepsy (PTE) is a debilitating neurological disorder that develops after traumatic brain injury (TBI). Early prediction of PTE remains challenging due to heterogeneous clinical data, limited positive cases, and…

Machine Learning · Computer Science 2026-04-17 Wenhui Cui , Nicholas Swingle , Anand A. Joshi , Dileep Nair , Richard M. Leahy
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