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Early detection of Alzheimer's Dementia (AD) and Mild Cognitive Impairment (MCI) is critical for timely intervention, yet current diagnostic approaches remain resource-intensive and invasive. Speech, encompassing both acoustic and…

Dementia diagnosis requires a series of different testing methods, which is complex and time-consuming. Early detection of dementia is crucial as it can prevent further deterioration of the condition. This paper utilizes a speech…

Computation and Language · Computer Science 2023-12-18 Zih-Jyun Lin , Yi-Ju Chen , Po-Chih Kuo , Likai Huang , Chaur-Jong Hu , Cheng-Yu Chen

Deep transformer models have been used to detect linguistic anomalies in patient transcripts for early Alzheimer's disease (AD) screening. While pre-trained neural language models (LMs) fine-tuned on AD transcripts perform well, little…

Computation and Language · Computer Science 2025-06-09 Zhecheng Sheng , Xiruo Ding , Brian Hur , Changye Li , Trevor Cohen , Serguei Pakhomov

Alzheimer's disease is a common cognitive disorder in the elderly. Early and accurate diagnosis of Alzheimer's disease (AD) has a major impact on the progress of research on dementia. At present, researchers have used machine learning…

Sound · Computer Science 2024-02-20 Xiaohui Zhang , Wenjie Fu , Mangui Liang

The detection of Alzheimer's disease (AD) from spontaneous speech has attracted increasing attention while the sparsity of training data remains an important issue. This paper handles the issue by knowledge transfer, specifically from both…

Computation and Language · Computer Science 2024-04-02 Ziyun Cui , Wen Wu , Wei-Qiang Zhang , Ji Wu , Chao Zhang

Fine-tuned Bidirectional Encoder Representations from Transformers (BERT)-based sequence classification models have proven to be effective for detecting Alzheimer's Disease (AD) from transcripts of human speech. However, previous research…

Computation and Language · Computer Science 2020-11-13 Aparna Balagopalan , Jekaterina Novikova

Alzheimer's disease (AD) is an irreversible and progressive brain disease that can be stopped or slowed down with medical treatment. Language changes serve as a sign that a patient's cognitive functions have been impacted, potentially…

Computation and Language · Computer Science 2018-04-19 Sweta Karlekar , Tong Niu , Mohit Bansal

We propose an automatic detection method of Alzheimer's diseases using a gated convolutional neural network (GCNN) from speech data. This GCNN can be trained with a relatively small amount of data and can capture the temporal information in…

Audio and Speech Processing · Electrical Eng. & Systems 2018-04-02 Tifani Warnita , Nakamasa Inoue , Koichi Shinoda

Dementia is a progressive cognitive syndrome with Alzheimer's disease (AD) as the leading cause. Conversation-based AD detection offers a cost-effective alternative to clinical methods, as language dysfunction is an early biomarker of AD.…

Computation and Language · Computer Science 2025-02-27 Arezo Shakeri , Mina Farmanbar , Krisztian Balog

Machine learning has shown promise for automatic detection of Alzheimer's disease (AD) through speech; however, efforts are hampered by a scarcity of data, especially in languages other than English. We propose a method to learn a…

Computation and Language · Computer Science 2019-06-04 Bai Li , Yi-Te Hsu , Frank Rudzicz

Early diagnosis of Alzheimer's Disease (AD) faces multiple data-related challenges, including high variability in patient data, limited access to specialized diagnostic tests, and overreliance on single-type indicators. These challenges are…

Quantitative Methods · Quantitative Biology 2025-03-05 Yizong Xing , Dhita Putri Pratama , Yuke Wang , Yufan Zhang , Brian E. Chapman

Self-supervised learning (SSL) based speech foundation models have been applied to a wide range of ASR tasks. However, their application to dysarthric and elderly speech via data-intensive parameter fine-tuning is confronted by in-domain…

Audio and Speech Processing · Electrical Eng. & Systems 2024-07-22 Shujie Hu , Xurong Xie , Mengzhe Geng , Zengrui Jin , Jiajun Deng , Guinan Li , Yi Wang , Mingyu Cui , Tianzi Wang , Helen Meng , Xunying Liu

Alzheimer's disease is estimated to affect around 50 million people worldwide and is rising rapidly, with a global economic burden of nearly a trillion dollars. This calls for scalable, cost-effective, and robust methods for detection of…

Audio and Speech Processing · Electrical Eng. & Systems 2020-09-03 Utkarsh Sarawgi , Wazeer Zulfikar , Nouran Soliman , Pattie Maes

Recent breakthroughs in Automatic Speech Recognition (ASR) have enabled fully automated Alzheimer's Disease (AD) detection using ASR transcripts. Nonetheless, the impact of ASR errors on AD detection remains poorly understood. This paper…

Audio and Speech Processing · Electrical Eng. & Systems 2025-05-27 Yin-Long Liu , Rui Feng , Jia-Xin Chen , Yi-Ming Wang , Jia-Hong Yuan , Zhen-Hua Ling

Alzheimers disease (AD) is a severe neurological brain disorder. It is not curable, but earlier detection can help improve symptoms in a great deal. The machine learning based approaches are popular and well motivated models for medical…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Lilia Lazli

Robust strategies for Alzheimer's disease (AD) detection are important, given the high prevalence of AD. In this paper, we study the performance and generalizability of three approaches for AD detection from speech on the recent ADReSSo…

Computation and Language · Computer Science 2022-09-16 Aparna Balagopalan , Jekaterina Novikova

This study addresses robust automatic speech recognition (ASR) by introducing a Conformer-based acoustic model. The proposed model builds on the wide residual bi-directional long short-term memory network (WRBN) with utterance-wise dropout…

Sound · Computer Science 2022-10-21 Yufeng Yang , Peidong Wang , DeLiang Wang

This study introduces Reverse-Speech-Finder (RSF), a groundbreaking neural network backtracking architecture designed to enhance Alzheimer's Disease (AD) diagnosis through speech analysis. Leveraging the power of pre-trained large language…

Machine Learning · Computer Science 2025-05-26 Victor OK Li , Yang Han , Jacqueline CK Lam , Lawrence YL Cheung

Early and accessible detection of Alzheimer's disease (AD) remains a major challenge, as current diagnostic methods often rely on costly and invasive biomarkers. Speech and language analysis has emerged as a promising non-invasive and…

Audio and Speech Processing · Electrical Eng. & Systems 2026-03-06 Franziska Braun , Christopher Witzl , Florian Hönig , Elmar Nöth , Tobias Bocklet , Korbinian Riedhammer

The average life expectancy is increasing globally due to advancements in medical technology, preventive health care, and a growing emphasis on gerontological health. Therefore, developing technologies that detect and track aging-associated…

Computational Engineering, Finance, and Science · Computer Science 2022-09-14 Saurav K. Aryal , Howard Prioleau , Legand Burge