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Alzheimer's disease and related dementias (ADRD) affect one in five adults over 60, yet more than half of individuals with cognitive decline remain undiagnosed. Speech-based assessments show promise for early detection, as phonetic motor…

In this paper, we combined linguistic complexity and (dis)fluency features with pretrained language models for the task of Alzheimer's disease detection of the 2021 ADReSSo (Alzheimer's Dementia Recognition through Spontaneous Speech)…

Computation and Language · Computer Science 2021-06-17 Yu Qiao , Xuefeng Yin , Daniel Wiechmann , Elma Kerz

Dementia is a syndrome, generally of a chronic nature characterized by a deterioration in cognitive function, especially in the geriatric population and is severe enough to impact their daily activities. Early diagnosis of dementia is…

Audio and Speech Processing · Electrical Eng. & Systems 2020-07-21 Rupayan Chakraborty , Meghna Pandharipande , Chitralekha Bhat , Sunil Kumar Kopparapu

Speech is usually used for constructing an automatic Alzheimer's dementia (AD) detection system, as the acoustic and linguistic abilities show a decline in people living with AD at the early stages. However, speech includes not only…

Audio and Speech Processing · Electrical Eng. & Systems 2024-10-11 Yilin Pan , Yanpei Shi , Yijia Zhang , Mingyu Lu

We uncover an underlying bias present in the audio recordings produced from the picture description task of the Pitt corpus, the largest publicly accessible database for Alzheimer's Disease (AD) detection research. Even by solely utilizing…

Audio and Speech Processing · Electrical Eng. & Systems 2024-06-12 Yin-Long Liu , Rui Feng , Jia-Hong Yuan , Zhen-Hua Ling

Alzheimer's disease (AD) is a progressive neurodegenerative disease most often associated with memory deficits and cognitive decline. With the aging population, there has been much interest in automated methods for cognitive impairment…

Audio and Speech Processing · Electrical Eng. & Systems 2023-03-07 Bastiaan Tamm , Rik Vandenberghe , Hugo Van hamme

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia, affecting memory, reasoning, communication, and daily functioning. Early diagnosis is particularly important, as timely intervention may…

Sound · Computer Science 2026-05-26 Loukas Ilias , Dimitris Askounis

With the global population aging rapidly, Alzheimer's disease (AD) is particularly prominent in older adults, which has an insidious onset and leads to a gradual, irreversible deterioration in cognitive domains (memory, communication,…

Audio and Speech Processing · Electrical Eng. & Systems 2023-03-15 Jinchao Li , Kaitao Song , Junan Li , Bo Zheng , Dongsheng Li , Xixin Wu , Xunying Liu , Helen Meng

Alzheimer's Disease (AD) is nowadays the most common form of dementia, and its automatic detection can help to identify symptoms at early stages, so that preventive actions can be carried out. Moreover, non-intrusive techniques based on…

Computation and Language · Computer Science 2020-11-21 Mireia Farrús , Joan Codina-Filbà

Alzheimer's disease (AD) constitutes a complex neurocognitive disease and is the main cause of dementia. Although many studies have been proposed targeting at diagnosing dementia through spontaneous speech, there are still limitations.…

Computation and Language · Computer Science 2023-08-24 Loukas Ilias , Dimitris Askounis

Automated diagnosis of Alzheimer Disease(AD) from brain imaging, such as magnetic resonance imaging (MRI), has become increasingly important and has attracted the community to contribute many deep learning methods. However, many of these…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Yifeng Wang , Ke Chen , Haohan Wang

Alzheimer's disease (AD) is an irreversible brain disease that can dramatically reduce quality of life, most commonly manifesting in older adults and eventually leading to the need for full-time care. Early detection is fundamental to…

Computation and Language · Computer Science 2019-06-14 Flavio Di Palo , Natalie Parde

Alzheimer's disease and related dementias(ADRD) affect nearly five million older adults in the United States, yet more than half remain undiagnosed. Speech-based natural language processing(NLP) offers a scalable approach for detecting…

Alzheimer's disease (AD) has become one of the most significant health challenges in an aging society. The use of spoken language-based AD detection methods has gained prevalence due to their scalability due to their scalability. Based on…

Computation and Language · Computer Science 2024-12-02 Junan Li , Yunxiang Li , Yuren Wang , Xixin Wu , Helen Meng

In light of the growing proportion of older individuals in our society, the timely diagnosis of Alzheimer's disease has become a crucial aspect of healthcare. In this paper, we propose a non-invasive and cost-effective detection method…

Human-Computer Interaction · Computer Science 2025-01-03 Tian Zheng , Xurong Xie , Xiaolan Peng , Hui Chen , Feng Tian

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to irreversible cognitive decline in memory and communication. Early detection of AD through speech analysis is crucial for delaying disease progression.…

Sound · Computer Science 2026-02-09 Yifan Gao , Long Guo , Hong Liu

Alzheimer's dementia (AD) is a neurodegenerative disorder with cognitive decline that commonly impacts language ability. This work extends the paired perplexity approach to detecting AD by using a recent large language model (LLM), the…

Computation and Language · Computer Science 2025-06-12 Yao Xiao , Heidi Christensen , Stefan Goetze

Cognitive decline is a sign of Alzheimer's disease (AD), and there is evidence that tracking a person's eye movement, using eye tracking devices, can be used for the automatic identification of early signs of cognitive decline. However,…

Computation and Language · Computer Science 2019-10-02 Bahman Mirheidari , Yilin Pan , Traci Walker , Markus Reuber , Annalena Venneri , Daniel Blackburn , Heidi Christensen

Compared to other clinical screening techniques, speech-and-language-based automated Alzheimer's disease (AD) detection methods are characterized by their non-invasiveness, cost-effectiveness, and convenience. Previous studies have…

Audio and Speech Processing · Electrical Eng. & Systems 2024-12-10 Yin-Long Liu , Rui Feng , Jia-Hong Yuan , Zhen-Hua Ling

Alzheimer s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, where early detection is essential for timely intervention and improved patient outcomes. Traditional diagnostic methods are…