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Wavefront shaping correction makes it possible to image fluorescent particles deep inside scattering tissue. This requires determining a correction mask to be placed in both excitation and emission paths. Standard approaches select…

Optics · Physics 2022-06-22 Dror Aizik , Ioannis Gkioulekas , Anat Levin

Non-invasive optical focusing inside scattering media is still a big challenge because inhomogeneous media scatter both incoming photons for focusing and outgoing photons for observation. Various approaches, utilizing non-linear…

Optics · Physics 2021-09-17 Dayan Li , Sujit Kumar Sahoo , Huy Quoc Lam , Dong Wang , Cuong Dang

Imaging through scattering is a pervasive and difficult problem in many biological applications. The high background and the exponentially attenuated target signals due to scattering fundamentally limits the imaging depth of fluorescence…

Signal Processing · Electrical Eng. & Systems 2023-12-11 Jeffrey Alido , Joseph Greene , Yujia Xue , Guorong Hu , Yunzhe Li , Mitchell Gilmore , Kevin J. Monk , Brett T. DiBenedictis , Ian G. Davison , Lei Tian

The presence of a scattering medium in the imaging path between an object and an observer is known to severely limit the visual acuity of the imaging system. We present an approach to circumvent the deleterious effects of scattering, by…

Over the past decade, optical wavefront shaping has been developed to focus light through highly opaque scattering layers, opening new possibilities for biomedical applications. To probe light intensity deep inside soft scattering media…

Optics · Physics 2025-08-25 Fei Xia , Ivo Leite , Robert Prevedel , Thomas Chaigne

Light scattering is the main limitation for optical imaging. However, light can be focused through or inside turbid media by spatially shaping the incident wavefront. Wavefront shaping is ultimately limited by the available photon budget.…

Instrumentation and Detectors · Physics 2021-03-24 Bahareh Mastiani , Ivo M. Vellekoop

Three-dimensional phase contrast imaging of multiply-scattering samples in X-ray and electron microscopy is extremely challenging, due to small numerical apertures, the unavailability of wavefront shaping optics, and the highly nonlinear…

Computational Physics · Physics 2021-06-02 Philipp M Pelz , Hamish G Brown , Jim Ciston , Scott D Findlay , Yaqian Zhang , Mary Scott , Colin Ophus

We present an optical wavefront shaping approach that allows tracking and localization of signal hidden inside or behind a scattering medium. The method combines traditional feedback based wavefront shaping together with a switch function,…

Scattering hinders the passage of light through random media and consequently limits the usefulness of optical techniques for sensing and imaging. Thus, methods for increasing the transmission of light through such random media are of…

Optics · Physics 2014-06-23 Curtis Jin , Raj Rao Nadakuditi , Eric Michielssen , Stephen Rand

Multiple light scattering hampers imaging objects in complex scattering media. Approaches used in real practices mainly aim to filter out multiple scattering obscuring the ballistic waves that travel straight through the scattering medium.…

We present a new approach for spatiotemporal focusing through complex scattering media by wave front shaping. Using a nonlinear feedback signal to shape the incident pulsed wave front, we show that the limit of a spatiotemporal matched…

Optical microscopy has so far been restricted to superficial layers, leaving many important biological questions unanswered. Random scattering causes the ballistic focus, which is conventionally used for image formation, to decay…

Optics · Physics 2012-08-28 Ke Si , Reto Fiolka , Meng Cui

Optical imaging through scattering media is a fundamental challenge in many applications. Recently, substantial breakthroughs such as imaging through biological tissues and looking around corners have been obtained by the use of…

Optics · Physics 2020-07-09 Tomer Yeminy , Ori Katz

In optical imaging, light propagation is affected by the inhomogeneities of the medium. Sample-induced aberrations and multiple scattering can strongly degrade the image resolution and contrast. Based on a dynamic correction of the incident…

Human ability to visualize an image is usually hindered by optical scattering. Recent extensive studies have promoted imaging technique through turbid materials to a reality where color image can be restored behind scattering media in real…

Optical approaches to fluorescent, spectroscopic, and morphological imaging have made exceptional advances in the last decade. Super-resolution imaging and wide-field multiphoton imaging are now underpinning major advances across the…

Wavefront shaping is a technique to study and control light transport inside scattering media. Wavefront shaping is considered to be applicable to any complex material, yet in most previous studies, the only sample geometries that are…

Imaging through scattering media is a fundamental and pervasive challenge in fields ranging from medical diagnostics to astronomy. A promising strategy to overcome this challenge is wavefront modulation, which induces measurement diversity…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Mingyang Xie , Haiyun Guo , Brandon Y. Feng , Lingbo Jin , Ashok Veeraraghavan , Christopher A. Metzler

We demonstrate focusing and imaging through a scattering medium noninvasively by using wavefront shaping. Our concept is based on utilizing the spatial fluorescence contrast which naturally exists in the hidden target object. By scanning…

Optics · Physics 2019-07-25 Anat Daniel , Dan Oron , Yaron Silberberg

The accurate characterisation of the 3D deformations of slender fibres and thin sheets in flow, is a key experimental challenge in the study of particle-laden flows. We propose a high-resolution, single-camera method to visualise…

Fluid Dynamics · Physics 2026-03-18 Tymoteusz Miara , Draga Pihler-Puzović , Matthias Heil , Anne Juel