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Cochran's $Q$ statistic is routinely used for testing heterogeneity in meta-analysis. Its expected value is also used for estimation of between-study variance $\tau^2$. Cochran's $Q$, or $Q_{IV}$, uses estimated inverse-variance weights…

Methodology · Statistics 2021-03-08 Ilyas Bakbergenuly , David C. Hoaglin , Elena Kulinskaya

A variety of problems in random-effects meta-analysis arise from the conventional $Q$ statistic, which uses estimated inverse-variance (IV) weights. In previous work on standardized mean difference and log-odds-ratio, we found superior…

Methodology · Statistics 2020-10-22 Elena Kulinskaya , David C. Hoaglin , Joseph Newman , Ilyas Bakbergenuly

A number of popular estimators of the between-study variance, $\tau^2$, are based on the Cochran's $Q$ statistic for testing heterogeneity in meta analysis. We introduce new point and interval estimators of $\tau^2$ for log-odds-ratio.…

Methodology · Statistics 2022-08-02 Elena Kulinskaya , David C. Hoaglin

Meta-analysis seeks to combine the results of several experiments in order to improve the accuracy of decisions. It is common to use a test for homogeneity to determine if the results of the several experiments are sufficiently similar to…

Methodology · Statistics 2009-08-01 Elena Kulinskaya , Michael B. Dollinger , Kirsten Bjørkestøl

Weighted histograms in Monte Carlo simulations are often used for the estimation of probability density functions. They are obtained as a result of random experiments with random events that have weights. In this paper, the bin contents of…

Data Analysis, Statistics and Probability · Physics 2010-03-02 N. D. Gagunashvili

This paper proposes a new deep-learning method to construct test statistics by computer vision and metrics learning. The application highlighted in this paper is applying computer vision on Q-Q plot to construct a new test statistic for…

Computer Vision and Pattern Recognition · Computer Science 2019-09-17 Ke-Wei Huang , Mengke Qiao , Xuanqi Liu , Siyuan Liu , Mingxi Dai

The univariate quantile-quantile (Q-Q) plot is a well-known graphical tool for examining whether two data sets are generated from the same distribution or not. It is also used to determine how well a specified probability distribution fits…

Statistics Theory · Mathematics 2014-07-07 Subhra Sankar Dhar , Biman Chakraborty , Probal Chaudhuri

Comparative binary outcome data are of fundamental interest in statistics and are often pooled in meta-analyses. Here we examine the simplest case where for each study there are two patient groups and a binary event of interest, giving rise…

Methodology · Statistics 2018-06-12 Rose Baker , Dan Jackson

Quantifying the heterogeneity is an important issue in meta-analysis, and among the existing measures, the $I^2$ statistic is most commonly used. In this paper, we first illustrate with a simple example that the $I^2$ statistic is heavily…

Methodology · Statistics 2025-06-10 Ke Yang , Enxuan Lin , Wangli Xu , Liping Zhu , Tiejun Tong

Popular measures of meta-analysis heterogeneity, such as $I^2$, cannot be considered measures of population heterogeneity since they are dependant on samples sizes within studies. The coefficient of variation (CV) recently introduced and…

Methodology · Statistics 2020-10-06 Maxwell Cairns , Luke Prendergast

Statistical data is often analyzed as a contingency table, sometimes with empty cells called zeros. Such sparse tables can be due to scarse observations classified in numerous categories, as for example in genetic association studies. Thus,…

Statistics Theory · Mathematics 2010-07-28 Audrey Finkler

Statistical data is often analyzed as a contingency table, sometimes with empty cells called zeros. Such sparse tables can be due to scarse observations classified in numerous categories, as for example in genetic association studies. Thus,…

Statistics Theory · Mathematics 2010-07-28 Audrey Finkler

When the individual studies assembled for a meta-analysis report means ($\mu_C$, $\mu_T$) for their treatment (T) and control (C) arms, but those data are on different scales or come from different instruments, the customary measure of…

Methodology · Statistics 2023-04-18 Elena Kulinskaya , David C. Hoaglin

Two modifications of the chi square test for comparing usual(unweighted) and weighted histograms and two weighted histograms are proposed. Numerical examples illustrate an application of the tests for the histograms with different…

Data Analysis, Statistics and Probability · Physics 2011-11-09 N. D. Gagunashvili

Random-effects meta-analysis requires an estimate of the between-study variance, $\tau^2$. We study methods of estimation of $\tau^2$ and its confidence interval in meta-analysis of odds ratio, and also the performance of related estimators…

Methodology · Statistics 2019-02-20 Ilyas Bakbergenuly , David C. Hoaglin , Elena Kulinskaya

Meta-analysis combines pertinent information from existing studies to provide an overall estimate of population parameters/effect sizes, as well as to quantify and explain the differences between studies. However, testing the between-study…

Methodology · Statistics 2020-11-13 Han Du , Ge Jiang , Zijun Ke

We describe an approximate statistical model for the sample variance distribution of the non-linear matter power spectrum that can be calibrated from limited numbers of simulations. Our model retains the common assumption of a multivariate…

Building on key papers that were published in special issues of Biometrics in 1957 and 1982 we propose and develop a three-aspect system for evaluating the effect of fitting covariates in the analysis of designed experiments, in particular…

Methodology · Statistics 2025-08-08 Stephen Senn , Franz König , Martin Posch

Histograms with weighted entries are used to estimate probability density functions. Computer simulation is the main application of this type of histograms. A review on chi-square tests for comparing weighted histograms is presented in this…

Data Analysis, Statistics and Probability · Physics 2017-04-27 Nikolai Gagunashvili

When an underlying logit based order dose-response model is considered with small or moderate sample sizes, the Cochran-Armitage (CA) test represents the most efficient test in the framework of the test-statistics applied with asymptotic…

Methodology · Statistics 2014-02-28 Nirian Martín , Raquel Mata
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