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Objective:Optoacoustic (photoacoustic) tomography is aimed at reconstructing maps of the initial pressure rise induced by the absorption of light pulses in tissue. In practice, due to inaccurate assumptions in the forward model, noise and…

Medical Physics · Physics 2019-01-21 Jaya Prakash , Subhamoy Mandal , Daniel Razansky , Vasilis Ntziachristos

The reconstruction task in photoacoustic tomography can vary a lot depending on measured targets, geometry, and especially the quantity we want to recover. Specifically, as the signal is generated due to the coupling of light and sound by…

Medical Physics · Physics 2023-11-28 Andreas Hauptmann , Tanja Tarvainen

Background: Photoacoustic Microscopy (PAM) integrates optical and acoustic imaging, offering enhanced penetration depth for detecting optical-absorbing components in tissues. Nonetheless, challenges arise in scanning large areas with high…

Medical Physics · Physics 2023-12-15 Irem Loc , Mehmet Burcin Unlu

Multiwavelength photoacoustic images encode information about a tissue's optical absorption distribution. This can be used to estimate its blood oxygen saturation distribution (sO2), an important physiological indicator of tissue health and…

Medical Physics · Physics 2023-05-09 Ciaran Bench , Ben T. Cox

In photoacoustic tomography (PAT), a hybrid imaging modality that is based on the acoustic detection of optical absorption from biological tissue exposed to a pulsed laser, a short pulse laser generates an initial pressure proportional to…

Numerical Analysis · Mathematics 2026-03-27 Sunghwan Moon , Anwesa Dey , Souvik Roy

Optical Coherence Tomography (OCT) is a widely used non-invasive imaging technique that provides detailed three-dimensional views of the retina, which are essential for the early and accurate diagnosis of ocular diseases. Consequently, OCT…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Huy Minh Nhat Nguyen , Triet Hoang Minh Dao , Chau Vinh Hoang Truong , Cuong Tuan Nguyen

In this paper we consider the problem of image reconstruction in optoacoustic tomography. In particular, we devise a deep neural architecture that can explicitly take into account the band-frequency information contained in the sinogram.…

Image and Video Processing · Electrical Eng. & Systems 2023-01-25 Martin G. Gonzalez , Matias Vera , Leonardo Rey Vega

Optical coherence tomography (OCT) and photoacoustic tomography (PAT) are emerging non-invasive biological and medical imaging techniques. It is a recent trend in experimental science to design experiments that perform PAT and OCT imaging…

Analysis of PDEs · Mathematics 2016-04-19 Peter Elbau , Leonidas Mindrinos , Otmar Scherzer

Optical Coherence Tomography (OCT) is a widely used non-invasive biomedical imaging modality that can rapidly provide volumetric images of samples. Here, we present a deep learning-based image reconstruction framework that can generate…

Image and Video Processing · Electrical Eng. & Systems 2021-07-30 Yijie Zhang , Tairan Liu , Manmohan Singh , Yilin Luo , Yair Rivenson , Kirill V. Larin , Aydogan Ozcan

Hyperspectral optoacoustic microscopy (OAM) enables obtaining images with label-free biomolecular contrast, offering excellent perspectives as a diagnostic tool to assess freshly excised and unprocessed tissues. However, time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2024-11-08 Constantin Berger , Myeongseop Kim , Lukas Scheel-Platz , Vasilis Ntziachristos , Dominik Jüstel , Miguel A. Pleitez

The Open Dataset of Audio Quality (ODAQ) was recently introduced to address the scarcity of openly available audio datasets with corresponding subjective quality scores. The dataset, released under permissive licenses, comprises audio…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-02 Sascha Dick , Christoph Thompson , Chih-Wei Wu , Matteo Torcoli , Pablo Delgado , Phillip A. Williams , Emanuel Habets

We consider image reconstruction in full-field photoacoustic tomography, where 2D projections of the full 3D acoustic pressure distribution at a given time T>0 are collected. We discuss existing results on the stability and uniqueness of…

Numerical Analysis · Mathematics 2024-12-20 Markus Haltmeier , Gerhard Zangerl , Robert Nuster , Linh V. Nguyen

This is the manuscript of the chapter for a planned Handbook of Mathematical Methods in Imaging that surveys the mathematical models, problems, and algorithms of the Thermoacoustic (TAT) and Photoacoustic (PAT) Tomography. TAT and PAT…

Analysis of PDEs · Mathematics 2011-10-04 Peter Kuchment , Leonid Kunyansky

Photo-acoustic tomography (PAT) aims to leverage the photo-acoustic coupling between optical absorption of light sources and ultrasound (US) emission to obtain high contrast reconstructions of optical parameters with the high resolution of…

Analysis of PDEs · Mathematics 2016-09-21 Guillaume Bal , Amir Moradifam

Photoacoustic tomography seeks to reconstruct an acoustic initial pressure distribution from the measurement of the ultrasound waveforms. Conventional methods assume a-prior knowledge of the sound speed distribution, which practically is…

Image and Video Processing · Electrical Eng. & Systems 2019-09-16 Hongming Shan , Christopher Wiedeman , Ge Wang , Yang Yang

Photoacoustic microscopy with large depth of focus is significant to the biomedical research. The conventional optical-resolution photoacoustic microscope (OR-PAM) suffers from limited depth of field (DoF) since the employed focused…

Image and Video Processing · Electrical Eng. & Systems 2020-09-07 Xianlin Song , Jianshuang Wei , Lingfang Song

In this tutorial, we combine the different scientific fields of information theory, thermodynamics, regularization theory and non-destructive imaging, especially for photoacoustic and photothermal imaging. The goal is to get a better…

Applied Physics · Physics 2020-12-02 Peter Burgholzer , Guenther Mayr , Gregor Thummerer , Markus Haltmeier

Simulation involves predicting responses of a physical system. In this article, we simulate opto-acoustic signals generated in a three-dimensional volume due to absorption of an optical pulse. A separable computational model is developed…

Computational Physics · Physics 2021-07-22 Jason Zalev , Michael C. Kolios

Optical coherence tomography (OCT) captures cross-sectional data and is used for the screening, monitoring, and treatment planning of retinal diseases. Technological developments to increase the speed of acquisition often results in systems…

Image and Video Processing · Electrical Eng. & Systems 2023-01-03 Timothy T. Yu , Da Ma , Jayden Cole , Myeong Jin Ju , Mirza F. Beg , Marinko V. Sarunic

Existing approaches to image reconstruction in photoacoustic computed tomography (PACT) with acoustically heterogeneous media are limited to weakly varying media, are computationally burdensome, and/or cannot effectively mitigate the…

Medical Physics · Physics 2013-03-25 Chao Huang , Kun Wang , Liming Nie , Lihong V. Wang , Mark A. Anastasio