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Limited-view artefacts are commonly present in optoacoustic tomography images, mainly due to practical geometrical and physical constraints imposed by the imaging systems as well as limited light penetration into large optically opaque…

Optics · Physics 2015-12-11 X L Dean-Ben , L Ding , D Razansky

Photoacoustic imaging and sensing have been studied extensively to probe the optical absorption of biological tissue in multiple scales ranging from large organs to small molecules. However, its elastic oscillation characterization is…

Optics · Physics 2015-09-21 Fei Gao , Xiaohua Feng , Yuanjin Zheng

Several centimeters below the skin lie multiple biomarkers, such as glucose, oxygenation, and blood flow. Monitoring these biomarkers regularly and in a non-invasive manner would enable early insight into metabolic status and vascular…

Medical Physics · Physics 2025-10-30 Talia Xu , Caitlin Smith , Charles Lo , Jami Shepherd , Gijs van Soest , Marco Zuniga

Optical coherence tomography angiography (OCTA) is a non-invasive imaging modality that can acquire high-resolution volumes of the retinal vasculature and aid the diagnosis of ocular, neurological and cardiac diseases. Segmenting the…

In this work we present the first application of software-defined optoelectronics (SDO) for bidimensional optoacoustic tomography (OAT). The SDO concept refers to optoelectronic systems where the functionality associated with the…

Signal Processing · Electrical Eng. & Systems 2023-05-10 Roberto Insabella , Martin Gonzalez , Lucas Riobo , Klaus Hass , Francisco Veiras

Photoacoustic (PA) imaging is a biomedical imaging modality capable of acquiring high-contrast images of optical absorption at depths much greater than traditional optical imaging techniques. However, practical instrumentation and geometry…

Computer Vision and Pattern Recognition · Computer Science 2021-06-02 Mengjie Guo , Hengrong Lan , Changchun Yang , Fei Gao

Optical imaging is commonly used for both scientific and technological applications across industry and academia. In image sensing, a measurement, such as of an object's position, is performed by computational analysis of a digitized image.…

Photoacoustic (PA) imaging has the potential to revolutionize functional medical imaging in healthcare due to the valuable information on tissue physiology contained in multispectral photoacoustic measurements. Clinical translation of the…

Deep learning in medical imaging faces obstacles: limited data diversity, ethical issues, high acquisition costs, and the need for precise annotations. Bleeding detection and localization during surgery is especially challenging due to the…

Image and Video Processing · Electrical Eng. & Systems 2025-06-18 Niran Nataraj , Maina Sogabe , Kenji Kawashima

Acousto-optic imaging (AOI) is a non-invasive method that uses acoustic modulation to map the light fluence inside biological tissue. In many AOI implementations, ultrasound pulses are used in a time-gated measurement to perform…

Image and Video Processing · Electrical Eng. & Systems 2020-04-17 Ahiad Levi , Sagi Monin , Evgeny Hahamovich , Aner Lev , Bruno G. Sfez , Amir Rosenthal

Optical coherence tomography (OCT) is capable of non-destructively obtaining cross-sectional information of samples with micrometer spatial resolution, which plays an important role in ophthalmology and endovascular medicine. Measuring OCT…

Medical Physics · Physics 2023-11-30 Yang Jianlong , Zhang Haoran , Liu Chang , Gu Chengfu

Estimation of blood oxygenation with spectroscopic photoacoustic imaging is a promising tool for several biomedical applications. For this method to be quantitative, it relies on an accurate method of the light fluence in the tissue. This…

Image and Video Processing · Electrical Eng. & Systems 2019-11-06 Geoffrey P. Luke , Kevin Hoffer-Hawlik , Austin C. Van Namen , Ruibo Shang

In this chapter a general mathematical model of Optical Coherence Tomography (OCT) is presented on the basis of the electromagnetic theory. OCT produces high resolution images of the inner structure of biological tissues. Images are…

Numerical Analysis · Mathematics 2016-04-19 Peter Elbau , Leonidas Mindrinos , Otmar Scherzer

Acousto-optic tomography (AOT) enables optical-contrast imaging deep inside scattering samples via localized ultrasound modulation of scattered light. However, the resolution of AOT is inherently limited by the ultrasound focus size,…

Optics · Physics 2018-12-12 Daniel Doktofsky , Moriya Rosenfeld , Ori Katz

Structural microvascular alterations and dysfunction serve as key disease indicators of cancer, diabetes, ischemic stroke, neurodegenerative disorders and many other conditions. In vivo visualization of the microvasculature has…

Biological Physics · Physics 2020-07-02 Xosé Luís Deán-Ben , Justine Robin , Ruiqing Ni , Daniel Razansky

Despite significant advances in artificial intelligence (AI) for computer vision, its application in medical imaging has been limited by the burden and limits of expert-generated labels. We used images from optical coherence tomography…

Computer Vision and Pattern Recognition · Computer Science 2018-02-27 Cecilia S. Lee , Ariel J. Tyring , Yue Wu , Sa Xiao , Ariel S. Rokem , Nicolaas P. Deruyter , Qinqin Zhang , Adnan Tufail , Ruikang K. Wang , Aaron Y. Lee

Image contrast in multispectral optoacoustic tomography (MSOT) can be severely reduced by electrical noise and interference in the acquired optoacoustic signals. Signal processing techniques have proven insufficient to remove the effects of…

Image and Video Processing · Electrical Eng. & Systems 2021-02-26 Christoph Dehner , Ivan Olefir , Kaushik Basak Chowdhury , Dominik Jüstel , Vasilis Ntziachristos

Photoacoustic imaging (PAI) and ultrasound imaging (USI) are important biomedical imaging techniques, due to their unique and complementary advantages in tissue's structure and function visualization. In this Letter, we proposed a coaxial…

Medical Physics · Physics 2024-11-12 Yunhui Jiang , Fan Zhang , Yuwei Zheng , Ruixi Sun , Fei Gao

Auditory attention to natural speech is a complex brain process. Its quantification from physiological signals can be valuable to improving and widening the range of applications of current brain-computer-interface systems, however it…

Human-Computer Interaction · Computer Science 2020-05-26 Nikesh Bajaj , Jesús Requena Carrión , Francesco Bellotti

Photoacoustic Tomography (PAT) is an emerging biomedical "imaging from coupled physics" technique, in which the image contrast is due to optical absorption, but the information is carried to the surface of the tissue as ultrasound pulses.…

Numerical Analysis · Mathematics 2016-11-03 Simon R. Arridge , Marta M. Betcke , Ben T. Cox , Felix Lucka , Brad E. Treeby