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A previous signal processing algorithm that aimed to enhance spectral changes (SCE) over time showed benefit for hearing-impaired (HI) listeners to recognize speech in background noise. In this work, the previous SCE was manipulated to…

Audio and Speech Processing · Electrical Eng. & Systems 2020-08-07 Xiang Li , Xin Tian , Henry Luo , Jinyu Qian , Xihong Wu , Dingsheng Luo , Jing Chen

Video-to-speech synthesis (also known as lip-to-speech) refers to the translation of silent lip movements into the corresponding audio. This task has received an increasing amount of attention due to its self-supervised nature (i.e., can be…

Recent Speech-to-Speech Translation (S2ST) systems achieve strong semantic accuracy yet consistently strip away non-verbal vocalizations (NVs), such as laughter and crying that convey pragmatic intent, which severely limits real-world…

Computation and Language · Computer Science 2026-04-21 Szu-Chi Chen , I-Ning Tsai , Yi-Cheng Lin , Sung-Feng Huang , Hung-yi Lee

Purpose: Large Language Models (LLMs) like GPT (Generative Pre-trained Transformer) from OpenAI and LLaMA (Large Language Model Meta AI) from Meta AI are increasingly recognized for their potential in the field of cheminformatics,…

Biomolecules · Quantitative Biology 2024-05-22 Shaghayegh Sadeghi , Alan Bui , Ali Forooghi , Jianguo Lu , Alioune Ngom

Current language model training commonly applies multi-task Supervised Fine-Tuning (SFT) using a homogeneous compute budget across all sub-datasets. This approach is fundamentally sub-optimal: heterogeneous learning dynamics cause…

Machine Learning · Computer Science 2026-03-30 Woosung Koh , Jeyoung Jeon , Youngjin Song , Yujin Cheon , Soowon Oh , Jaehyeong Choi , Se-Young Yun

Recent advancements in biological research leverage the integration of molecules, proteins, and natural language to enhance drug discovery. However, current models exhibit several limitations, such as the generation of invalid molecular…

Computation and Language · Computer Science 2024-01-30 Qizhi Pei , Wei Zhang , Jinhua Zhu , Kehan Wu , Kaiyuan Gao , Lijun Wu , Yingce Xia , Rui Yan

Natural language processing (NLP) enables the understanding and generation of meaningful human language, typically using a pre-trained complex architecture on a large dataset to learn the language and next fine-tune its weights to implement…

Computation and Language · Computer Science 2025-09-04 Yarden Tzach , Ronit D. Gross , Ella Koresh , Shalom Rosner , Or Shpringer , Tal Halevi , Ido Kanter

Chemical representation learning has gained increasing interest due to the limited availability of supervised data in fields such as drug and materials design. This interest particularly extends to chemical language representation learning,…

Chemical Physics · Physics 2024-08-06 Jun-Hyung Park , Yeachan Kim , Mingyu Lee , Hyuntae Park , SangKeun Lee

Large language models (LLMs) offer a powerful opportunity to simulate the results of social science experiments. In this work, we demonstrate that finetuning LLMs directly on individual-level responses from past experiments meaningfully…

Machine Learning · Computer Science 2025-11-07 Akaash Kolluri , Shengguang Wu , Joon Sung Park , Michael S. Bernstein

Auto-regressive speech-text models pre-trained on interleaved text tokens and discretized speech tokens demonstrate strong speech understanding and generation, yet remain substantially less compute-efficient than text LLMs, partly due to…

Computation and Language · Computer Science 2026-03-11 Yen-Ju Lu , Yashesh Gaur , Wei Zhou , Benjamin Muller , Jesus Villalba , Najim Dehak , Luke Zettlemoyer , Gargi Ghosh , Mike Lewis , Srinivasan Iyer , Duc Le

One reason pretraining on self-supervised linguistic tasks is effective is that it teaches models features that are helpful for language understanding. However, we want pretrained models to learn not only to represent linguistic features,…

Computation and Language · Computer Science 2020-10-13 Alex Warstadt , Yian Zhang , Haau-Sing Li , Haokun Liu , Samuel R. Bowman

Proteins perform their functions usually by interacting with other proteins. Predicting which proteins interact is a fundamental problem. Experimental methods are slow, expensive, and have a high rate of error. Many computational methods…

Biomolecules · Quantitative Biology 2017-05-22 Yiwei Li , Lucian Ilie

Pretraining sentence encoders with language modeling and related unsupervised tasks has recently been shown to be very effective for language understanding tasks. By supplementing language model-style pretraining with further training on…

Computation and Language · Computer Science 2019-03-01 Jason Phang , Thibault Févry , Samuel R. Bowman

Therapeutic peptides have emerged as a pivotal modality in modern drug discovery, occupying a chemically and topologically rich space. While accurate prediction of their physicochemical properties is essential for accelerating peptide…

Machine Learning · Computer Science 2025-12-30 Seungeon Lee , Takuto Koyama , Itsuki Maeda , Shigeyuki Matsumoto , Yasushi Okuno

Teaching robots desired skills in real-world environments remains challenging, especially for non-experts. A key bottleneck is that collecting robotic data often requires expertise or specialized hardware, limiting accessibility and…

Robotics · Computer Science 2025-05-13 Gi-Cheon Kang , Junghyun Kim , Kyuhwan Shim , Jun Ki Lee , Byoung-Tak Zhang

We introduce BitFit, a sparse-finetuning method where only the bias-terms of the model (or a subset of them) are being modified. We show that with small-to-medium training data, applying BitFit on pre-trained BERT models is competitive with…

Machine Learning · Computer Science 2026-01-30 Elad Ben-Zaken , Shauli Ravfogel , Yoav Goldberg

X-ray Photoelectron Spectroscopy (XPS) is a crucial technique for material surface analysis, yet interpreting its spectra is often challenging for both human analysts and automated methods due to the prevalence of variable spectral shifts…

Materials Science · Physics 2026-03-06 Issa Saddiq , Yuxin Fan , Robert G. Palgrave , Mark A. Isaacs , David Morgan , Keith T. Butler

Effective representation of molecules is a crucial factor affecting the performance of artificial intelligence models. This study introduces a flexible, fragment-based, multiscale molecular representation framework called t-SMILES…

Machine Learning · Computer Science 2024-05-22 Juan-Ni Wu , Tong Wang , Yue Chen , Li-Juan Tang , Hai-Long Wu , Ru-Qin Yu

Code-switching automatic speech recognition (CS-ASR) presents unique challenges due to language confusion introduced by spontaneous intra-sentence switching and accent bias that blurs the phonetic boundaries. Although the constituent…

Audio and Speech Processing · Electrical Eng. & Systems 2026-03-18 Hexin Liu , Haoyang Zhang , Qiquan Zhang , Xiangyu Zhang , Dongyuan Shi , Eng Siong Chng , Haizhou Li

Over the recent years, large pretrained language models (LM) have revolutionized the field of natural language processing (NLP). However, while pretraining on general language has been shown to work very well for common language, it has…

Computation and Language · Computer Science 2022-12-20 Nicolas Webersinke , Mathias Kraus , Julia Anna Bingler , Markus Leippold
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