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Cell monolayers are a central model system to tissue biophysics. In vivo, epithelial tissues are curved on the scale of microns, and curvature's role in the onset of spontaneous tissue flows is still not well-understood. Here, we present a…

Biological Physics · Physics 2022-09-21 Samuel Bell , Shao-Zhen Lin , Jean-François Rupprecht , Jacques Prost

We construct the equations of motion for the coupled dynamics of order parameter and concentration for the nematic phase of driven particles on a solid surface, and show that they imply (i) giant number fluctuations, with a standard…

Soft Condensed Matter · Physics 2009-11-07 Sriram Ramaswamy , R. Aditi Simha , John Toner

We use a continuum, two-fluid approach to study a mixture of two active nematic fluids. Even in the absence of thermodynamically-driven ordering, for mixtures of different activities we observe turbulent microphase separation, where domains…

Soft Condensed Matter · Physics 2025-02-03 Saraswat Bhattacharyya , Julia M. Yeomans

A surface in contact with the isotropic phase of a passive liquid crystal can induce nematic order over distances that range from microscopic to macroscopic when the nematic-isotropic interface undergoes an orientational-wetting transition.…

Soft Condensed Matter · Physics 2024-03-18 Rodrigo C. V. Coelho , José A. Moreira , Duarte M. C. Pedro , Margarida M. Telo da Gama

We investigate the emergence of orientational order among +1/2 disclinations in active nematic liquid crystals. Using a combination of theoretical and experimental methods, we show that +1/2 disclinations have short-range antiferromagnetic…

Soft Condensed Matter · Physics 2021-11-08 D. J. G. Pearce , J. Nambisan , P. W. Ellis , A. Fernandez-Nieves , L. Giomi

In two-dimensional tissues, such as developing germ layers, pair-wise forces (or active stresses) arise from the contractile activity of the cytoskeleton, with dissipation provided by the three-dimensional surroundings. We show analytically…

Soft Condensed Matter · Physics 2025-07-17 Yann-Edwin Keta , Silke Henkes

We use numerical simulations and linear stability analysis to study the dynamics of an active liquid crystal film on a substrate in the regime where the passive system would be isotropic. Extensile activity builds up local orientational…

Soft Condensed Matter · Physics 2023-09-26 Fernando Caballero , Zhihong You , M. Cristina Marchetti

Active fluids exhibit complex turbulent-like flows at low Reynolds number. Recent work predicted that 2d active nematic turbulence follows universal scaling laws. However, experimentally testing these predictions is conditioned by the…

With exquisite precision and reproducibility, cells orchestrate the cooperative action of thousands of nanometer-sized molecular motors to carry out mechanical tasks at much larger length scales, such as cell motility, division and…

Soft Condensed Matter · Physics 2013-01-08 Tim Sanchez , Daniel T. N. Chen , Stephen J. DeCamp , Michael Heymann , Zvonimir Dogic

Active matter encompasses different nonequilibrium systems in which individual constituents convert energy into non-conservative forces or motion at the microscale. This review provides an elementary introduction to the role of topology in…

Soft Condensed Matter · Physics 2022-06-28 Suraj Shankar , Anton Souslov , Mark J. Bowick , M. Cristina Marchetti , Vincenzo Vitelli

The collective effects of microswimmers in active suspensions result in active turbulence, a spatiotemporally chaotic dynamics at mesoscale, which is characterized by the presence of vortices and jets at scales much larger than the…

Fluid Dynamics · Physics 2020-02-24 Moritz Linkmann , M. Cristina Marchetti , Guido Boffetta , Bruno Eckhardt

Drops of active liquid crystal have recently shown the ability to self-propel, which was associated with topological defects in the orientation of active filaments [Sanchez {\em et al.}, Nature {\bf 491}, 431 (2013)]. Here, we study the…

Soft Condensed Matter · Physics 2016-07-05 Diana Khoromskaia , Gareth P. Alexander

In soft matter, the phase of nematic liquid crystals can be made from anisotropic molecules in single component materials, or as a suspension of mesoscopic nematogens. The later offers more versatility in the experimental design of complex…

Soft Condensed Matter · Physics 2025-10-23 Mathieu Dedenon

We investigate the dynamics of mobile inclusions embedded in 2D active nematics. The interplay between the inclusion shape, the boundary-induced nematic order, and the autonomous flow powers the inclusion motion. Disks and achiral gears…

Soft Condensed Matter · Physics 2023-06-16 Sattvic Ray , Jie Zhang , Zvonimir Dogic

Active nematic systems consist of rod-like internally driven subunits that interact with one another to form large-scale coherent flows. They are important examples of far-from-equilibrium fluids, which exhibit a wealth of nonlinear…

Soft Condensed Matter · Physics 2025-06-27 Kevin A. Mitchell , Md Mainul Hasan Sabbir , Sean Ricarte , Brandon Klein , Daniel A. Beller

Order and alignment are ubiquitous in growing colonies of rod-shaped bacteria due to the nematic properties of the constituent particles. These effects are the result of the active stresses generated by growth, passive mechanical…

Soft Condensed Matter · Physics 2022-07-07 Jonas Isensee , Lukas Hupe , Ramin Golestanian , Philip Bittihn

We consider a phenomenological continuum theory for an extensile, overdamped active nematic liquid crystal, applicable in the dense regime. Constructed from general principles, the theory is universal, with parameters independent of any…

Soft Condensed Matter · Physics 2015-06-12 Elias Putzig , Gabriel S. Redner , Arvind Baskaran , Aparna Baskaran

From the mitotic spindle up to tissues and biofilms, many biological systems behave as active droplets, which often break symmetry and change shape spontaneously. Here, I show that active nematic droplets can experience a fingering…

Soft Condensed Matter · Physics 2022-06-07 Ricard Alert

In densely-packed two-dimensional systems of growing cells, such as rod-shaped bacteria, a number of experimental and numerical studies report distinct patterns of nematic orientational order in the presence of confinement. So far, these…

Soft Condensed Matter · Physics 2025-06-13 Lukas Hupe , Jonas Isensee , Ramin Golestanian , Philip Bittihn

Active nematics are an important new paradigm in soft condensed matter systems. They consist of rod-like components with an internal driving force pushing them out of equilibrium. The resulting fluid motion exhibits chaotic advection, in…