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The convergence of statistical learning and molecular physics is transforming our approach to modeling biomolecular systems. Physics-informed machine learning (PIML) offers a systematic framework that integrates data-driven inference with…

Biomolecules · Quantitative Biology 2025-11-11 Aaryesh Deshpande

Deep learning has been the most popular machine learning method in the last few years. In this chapter, we present the application of deep learning and physics-informed neural networks concerning structural mechanics and vibration problems.…

Machine Learning · Computer Science 2022-02-23 Ehsan Haghighat , Ali Can Bekar , Erdogan Madenci , Ruben Juanes

Deep learning is transforming many areas in science, and it has great potential in modeling molecular systems. However, unlike the mature deployment of deep learning in computer vision and natural language processing, its development in…

Computational Physics · Physics 2021-03-19 Jun Zhang , Yao-Kun Lei , Zhen Zhang , Junhan Chang , Maodong Li , Xu Han , Lijiang Yang , Yi Isaac Yang , Yi Qin Gao

We demonstrate that embedding physics-driven constraints into machine learning process can dramatically improve accuracy and generalizability of the resulting model. Physics-informed learning is illustrated on the example of analysis of…

Computational Physics · Physics 2021-12-16 Abantika Ghosh , Mohannad Elhamod , Jie Bu , Wei-Cheng Lee , Anuj Karpatne , Viktor A Podolskiy

The rapidly increasing computational demands for artificial intelligence (AI) have spurred the exploration of computing principles beyond conventional digital computers. Physical neural networks (PNNs) offer efficient neuromorphic…

In a neuron network, synapses update individually using local information, allowing for entirely decentralized learning. In contrast, elements in an artificial neural network (ANN) are typically updated simultaneously using a central…

Soft Condensed Matter · Physics 2022-12-05 Jacob F Wycoff , Sam Dillavou , Menachem Stern , Andrea J Liu , Douglas J Durian

The success of reinforcement learning for real world robotics has been, in many cases limited to instrumented laboratory scenarios, often requiring arduous human effort and oversight to enable continuous learning. In this work, we discuss…

Machine Learning · Computer Science 2020-04-28 Henry Zhu , Justin Yu , Abhishek Gupta , Dhruv Shah , Kristian Hartikainen , Avi Singh , Vikash Kumar , Sergey Levine

Computation is becoming an increasingly important part of physics education. However, there are currently few theories of learning that can be used to help explain and predict the unique challenges and affordances associated with…

Physics Education · Physics 2020-01-01 Tor Ole B. Odden , Elise Lockwood , Marcos D. Caballero

Physics-informed neural networks (PINNs) have emerged as a promising approach to solving partial differential equations (PDEs) using neural networks, particularly in data-scarce scenarios, due to their unsupervised training capability.…

Machine Learning · Computer Science 2025-03-25 Edgar Torres , Jonathan Schiefer , Mathias Niepert

The field of fluid mechanics is rapidly advancing, driven by unprecedented volumes of data from field measurements, experiments and large-scale simulations at multiple spatiotemporal scales. Machine learning offers a wealth of techniques to…

Fluid Dynamics · Physics 2020-02-19 Steven Brunton , Bernd Noack , Petros Koumoutsakos

We outline a way for an agent to learn the dispositions of a particular individual through inverse reinforcement learning where the state space at time t includes an fMRI scan of the individual, to represent his brain state at that time.…

Other Computer Science · Computer Science 2019-07-14 Tofara Moyo

Weight-sharing is one of the pillars behind Convolutional Neural Networks and their successes. However, in physical neural systems such as the brain, weight-sharing is implausible. This discrepancy raises the fundamental question of whether…

Machine Learning · Computer Science 2019-10-08 Jordan Ott , Erik Linstead , Nicholas LaHaye , Pierre Baldi

We introduce conditional PINNs (physics informed neural networks) for estimating the solution of classes of eigenvalue problems. The concept of PINNs is expanded to learn not only the solution of one particular differential equation but the…

Fuelled by increasing computer power and algorithmic advances, machine learning techniques have become powerful tools for finding patterns in data. Since quantum systems produce counter-intuitive patterns believed not to be efficiently…

Quantum Physics · Physics 2018-05-14 Jacob Biamonte , Peter Wittek , Nicola Pancotti , Patrick Rebentrost , Nathan Wiebe , Seth Lloyd

While reinforcement learning (RL) has the potential to enable robots to autonomously acquire a wide range of skills, in practice, RL usually requires manual, per-task engineering of reward functions, especially in real world settings where…

Robotics · Computer Science 2019-02-15 Tianhe Yu , Gleb Shevchuk , Dorsa Sadigh , Chelsea Finn

The training of autonomous agents often requires expensive and unsafe trial-and-error interactions with the environment. Nowadays several data sets containing recorded experiences of intelligent agents performing various tasks, spanning…

Machine Learning · Computer Science 2020-10-06 Giorgio Angelotti , Nicolas Drougard , Caroline Ponzoni Carvalho Chanel

Neutrino experiments study the least understood of the Standard Model particles by observing their direct interactions with matter or searching for ultra-rare signals. The study of neutrinos typically requires overcoming large backgrounds,…

Computational Physics · Physics 2020-12-30 Fernanda Psihas , Micah Groh , Christopher Tunnell , Karl Warburton

Deep learning has arguably achieved tremendous success in recent years. In simple words, deep learning uses the composition of many nonlinear functions to model the complex dependency between input features and labels. While neural networks…

Machine Learning · Statistics 2019-04-16 Jianqing Fan , Cong Ma , Yiqiao Zhong

A fundamental aspect of learning in biological neural networks is the plasticity property which allows them to modify their configurations during their lifetime. Hebbian learning is a biologically plausible mechanism for modeling the…

Neural and Evolutionary Computing · Computer Science 2021-03-16 Anil Yaman , Giovanni Iacca , Decebal Constantin Mocanu , Matt Coler , George Fletcher , Mykola Pechenizkiy

Despite their apparent diversity, modern machine learning methods can be reduced to a remarkably simple core principle: learning is achieved by continuously optimizing parameters to minimize or maximize a scalar objective function. This…

Machine Learning · Computer Science 2026-02-24 Sheng Ran
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