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Multiple instance learning (MIL) has emerged as a powerful framework for weakly supervised whole slide image (WSI) classification, enabling slide-level predictions without requiring detailed patch-level annotations. Despite its success, a…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Bryan Wong , Mun Yong Yi

Multiple-instance learning is a subset of weakly supervised learning where labels are applied to sets of instances rather than the instances themselves. Under the standard assumption, a set is positive only there is if at least one instance…

Machine Learning · Computer Science 2021-05-05 Daniel Grahn

Weakly supervised image segmentation approaches in the literature usually achieve high segmentation performance using tight bounding box supervision and decrease the performance greatly when supervised by loose bounding boxes. However,…

Computer Vision and Pattern Recognition · Computer Science 2023-01-31 Juan Wang , Bin Xia

Self-paced learning and hard example mining re-weight training instances to improve learning accuracy. This paper presents two improved alternatives based on lightweight estimates of sample uncertainty in stochastic gradient descent (SGD):…

Machine Learning · Statistics 2018-01-09 Haw-Shiuan Chang , Erik Learned-Miller , Andrew McCallum

We address the challenging problem of whole slide image (WSI) classification. WSIs have very high resolutions and usually lack localized annotations. WSI classification can be cast as a multiple instance learning (MIL) problem when only…

Computer Vision and Pattern Recognition · Computer Science 2021-04-05 Bin Li , Yin Li , Kevin W. Eliceiri

Recent works have shown that deep neural networks benefit from multi-task learning by learning a shared representation across several related tasks. However, performance of such systems depend on relative weighting between various losses…

Computer Vision and Pattern Recognition · Computer Science 2021-06-14 Pavan Kumar Anasosalu Vasu , Shreyas Saxena , Oncel Tuzel

Active learning has demonstrated data efficiency in many fields. Existing active learning algorithms, especially in the context of batch-mode deep Bayesian active models, rely heavily on the quality of uncertainty estimations of the model,…

Machine Learning · Computer Science 2023-02-22 Renyu Zhang , Aly A. Khan , Robert L. Grossman , Yuxin Chen

Despite the great promise of machine-learning algorithms to classify and predict astrophysical parameters for the vast numbers of astrophysical sources and transients observed in large-scale surveys, the peculiarities of the training data…

Instrumentation and Methods for Astrophysics · Physics 2015-05-28 Joseph W. Richards , Dan L. Starr , Henrik Brink , Adam A. Miller , Joshua S. Bloom , Nathaniel R. Butler , J. Berian James , James P. Long , John Rice

Collecting large-scale medical datasets with fine-grained annotations is time-consuming and requires experts. For this reason, weakly supervised learning aims at optimising machine learning models using weaker forms of annotations, such as…

Computer Vision and Pattern Recognition · Computer Science 2021-08-27 Gabriele Valvano , Andrea Leo , Sotirios A. Tsaftaris

A common assumption in machine learning is that samples are independently and identically distributed (i.i.d). However, the contributions of different samples are not identical in training. Some samples are difficult to learn and some…

Machine Learning · Computer Science 2021-11-23 Ou Wu , Weiyao Zhu , Yingjun Deng , Haixiang Zhang , Qinghu Hou

Dealing with high variance is a significant challenge in model-free reinforcement learning (RL). Existing methods are unreliable, exhibiting high variance in performance from run to run using different initializations/seeds. Focusing on…

Machine Learning · Computer Science 2019-05-15 Richard Cheng , Abhinav Verma , Gabor Orosz , Swarat Chaudhuri , Yisong Yue , Joel W. Burdick

Recent progress in deep latent variable models has largely been driven by the development of flexible and scalable variational inference methods. Variational training of this type involves maximizing a lower bound on the log-likelihood,…

Machine Learning · Computer Science 2016-06-02 Andriy Mnih , Danilo J. Rezende

This paper introduces MAD-MIL, a Multi-head Attention-based Deep Multiple Instance Learning model, designed for weakly supervised Whole Slide Images (WSIs) classification in digital pathology. Inspired by the multi-head attention mechanism…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Hassan Keshvarikhojasteh , Josien Pluim , Mitko Veta

In statistical learning, many problem formulations have been proposed so far, such as multi-class learning, complementarily labeled learning, multi-label learning, multi-task learning, which provide theoretical models for various real-world…

Machine Learning · Computer Science 2022-11-14 Daiki Suehiro , Eiji Takimoto

Inference for models with recursively defined likelihoods is computationally demanding, limiting scalability to large datasets. We propose a stabilised weighted subsampling methodology for accelerated inference based on an unbiased…

Methodology · Statistics 2026-05-14 Matias Quiroz , Aishwarya Bhaskaran , Zixuan Wang , Thomas Goodwin

Given a finite set of sample points, meta-learning algorithms aim to learn an optimal adaptation strategy for new, unseen tasks. Often, this data can be ambiguous as it might belong to different tasks concurrently. This is particularly the…

Machine Learning · Computer Science 2024-10-24 Alfredo Reichlin , Gustaf Tegnér , Miguel Vasco , Hang Yin , Mårten Björkman , Danica Kragic

We propose a novel framework to classify large-scale time series data with long duration. Long time seriesclassification (L-TSC) is a challenging problem because the dataoften contains a large amount of irrelevant information to…

Artificial Intelligence · Computer Science 2021-11-23 Yuansheng Zhu , Weishi Shi , Deep Shankar Pandey , Yang Liu , Xiaofan Que , Daniel E. Krutz , Qi Yu

In this paper, we propose a balancing training method to address problems in imbalanced data learning. To this end, we derive a new loss used in the balancing training phase that alleviates the influence of samples that cause an overfitted…

Computer Vision and Pattern Recognition · Computer Science 2021-10-14 Seulki Park , Jongin Lim , Younghan Jeon , Jin Young Choi

The goal of regression and classification methods in supervised learning is to minimize the empirical risk, that is, the expectation of some loss function quantifying the prediction error under the empirical distribution. When facing scarce…

Optimization and Control · Mathematics 2019-07-15 Soroosh Shafieezadeh-Abadeh , Daniel Kuhn , Peyman Mohajerin Esfahani

Whole slide image (WSI) classification is a critical task in computational pathology, requiring the processing of gigapixel-sized images, which is challenging for current deep-learning methods. Current state of the art methods are based on…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Jingwei Zhang , Saarthak Kapse , Ke Ma , Prateek Prasanna , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras