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Medical image segmentation is an important task for computer aided diagnosis. Pixelwise manual annotations of large datasets require high expertise and is time consuming. Conventional data augmentations have limited benefit by not fully…

The automatic detection and localization of anatomical features in retinal imaging data are relevant for many aspects. In this work, we follow a data-centric approach to optimize classifier training for optic nerve head detection and…

Automatically identifying the structural substrates underlying cardiac abnormalities can potentially provide real-time guidance for interventional procedures. With the knowledge of cardiac tissue substrates, the treatment of complex…

Recent Alzheimer's disease (AD) patient studies have focused on retinal analysis, as the retina is the only part of the central nervous system which can be imaged non-invasively by optical methods. However as this is a relatively new…

Large, fine-grained image segmentation datasets, annotated at pixel-level, are difficult to obtain, particularly in medical imaging, where annotations also require expert knowledge. Weakly-supervised learning can train models by relying on…

In medical applications, the same anatomical structures may be observed in multiple modalities despite the different image characteristics. Currently, most deep models for multimodal segmentation rely on paired registered images. However,…

Glaucoma is a progressive eye disease that leads to optic nerve damage, causing irreversible vision loss if left untreated. Optical coherence tomography (OCT) has become a crucial tool for glaucoma diagnosis, offering high-resolution 3D…

Advances in optical coherence tomography (OCT) have enabled noninvasive imaging of substructures of the human retina with high spatial resolution. OCT examinations are now a standard procedure in clinics and an integral part of ophthalmic…

With the introduction of spectral-domain optical coherence tomography (OCT), much larger image datasets are routinely acquired compared to what was possible using the previous generation of time-domain OCT. Thus, the need for 3-D…

The state-of-the-art approaches in Generative Adversarial Networks (GANs) are able to learn a mapping function from one image domain to another with unpaired image data. However, these methods often produce artifacts and can only be able to…

3D to 2D retinal vessel segmentation is a challenging problem in Optical Coherence Tomography Angiography (OCTA) images. Accurate retinal vessel segmentation is important for the diagnosis and prevention of ophthalmic diseases. However,…

The automatic segmentation of retinal layer structures enables clinically-relevant quantification and monitoring of eye disorders over time in OCT imaging. Eyes with late-stage diseases are particularly challenging to segment, as their…

A major cause of irreversible visual impairment is angle-closure glaucoma, which can be screened through imagery from Anterior Segment Optical Coherence Tomography (AS-OCT). Previous computational diagnostic techniques address this…

Accurate segmentation of retinal fluids in 3D Optical Coherence Tomography images is key for diagnosis and personalized treatment of eye diseases. While deep learning has been successful at this task, trained supervised models often fail…

The utilisation of deep learning segmentation algorithms that learn complex organs and tissue patterns and extract essential regions of interest from the noisy background to improve the visual ability for medical image diagnosis has…

Automatic segmentation of fluid in Optical Coherence Tomography (OCT) images is beneficial for ophthalmologists to make an accurate diagnosis. Although semi-supervised OCT fluid segmentation networks enhance their performance by introducing…

Purpose: To remove retinal shadows from optical coherence tomography (OCT) images of the optic nerve head(ONH). Methods:2328 OCT images acquired through the center of the ONH using a Spectralis OCT machine for both eyes of 13 subjects were…

Multiple-surface segmentation in Optical Coherence Tomography (OCT) images is a challenge problem, further complicated by the frequent presence of weak image boundaries. Recently, many deep learning (DL) based methods have been developed…

Unsupervised learning can discover various unseen abnormalities, relying on large-scale unannotated medical images of healthy subjects. Towards this, unsupervised methods reconstruct a 2D/3D single medical image to detect outliers either in…

With the development of convolutional neural network, deep learning has shown its success for retinal disease detection from optical coherence tomography (OCT) images. However, deep learning often relies on large scale labelled data for…