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Age-related Macular Degeneration (AMD) is a prevalent eye condition affecting visual acuity. Anti-vascular endothelial growth factor (anti-VEGF) treatments have been effective in slowing the progression of neovascular AMD, with better…

Diabetic retinopathy (DR) is a leading cause of vision loss, requiring early and accurate assessment to prevent irreversible damage. Spectral Domain Optical Coherence Tomography (SD-OCT) enables high-resolution retinal imaging, but…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 S. Chen , D. Ma , M. Raviselvan , S. Sundaramoorthy , K. Popuri , M. J. Ju , M. V. Sarunic , D. Ratra , M. F. Beg

Optical Coherence Tomography (OCT) is a non-invasive imaging modality essential for diagnosing various eye diseases. Despite its clinical significance, developing OCT-based diagnostic tools faces challenges, such as limited public datasets,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-30 Mohammadreza Saraei , Igor Kozak , Eung-Joo Lee

Optical coherence tomography angiography (OCTA) is a novel non-invasive imaging technique that allows visualizations of vasculature and foveal avascular zone (FAZ) across retinal layers. Clinical researches suggest that the morphology and…

Image and Video Processing · Electrical Eng. & Systems 2021-07-14 Li Lin , Zhonghua Wang , Jiewei Wu , Yijin Huang , Junyan Lyu , Pujin Cheng , Jiong Wu , Xiaoying Tang

Retinal vessel segmentation is a vital early detection method for several severe ocular diseases. Despite significant progress in retinal vessel segmentation with the advancement of Neural Networks, there are still challenges to overcome.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-08 Shuang Zeng , Chee Hong Lee , Micky C Nnamdi , Wenqi Shi , J Ben Tamo , Lei Zhu , Hangzhou He , Xinliang Zhang , Qian Chen , May D. Wang , Yanye Lu , Qiushi Ren

Manually inspecting polyps from a colonoscopy for colorectal cancer or performing a biopsy on skin lesions for skin cancer are time-consuming, laborious, and complex procedures. Automatic medical image segmentation aims to expedite this…

Image and Video Processing · Electrical Eng. & Systems 2023-06-27 Akib Mohammed Khan , Alif Ashrafee , Fahim Shahriar Khan , Md. Bakhtiar Hasan , Md. Hasanul Kabir

Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

Optical coherence tomography (OCT) is a non-invasive imaging technology which can provide micrometer-resolution cross-sectional images of the inner structures of the eye. It is widely used for the diagnosis of ophthalmic diseases with…

Image and Video Processing · Electrical Eng. & Systems 2019-12-10 Donghuan Lu , Morgan Heisler , Da Ma , Setareh Dabiri , Sieun Lee , Gavin Weiguang Ding , Marinko V. Sarunic , Mirza Faisal Beg

Optical coherence tomography (OCT) is commonly used to analyze retinal layers for assessment of ocular diseases. In this paper, we propose a method for retinal layer segmentation and quantification of uncertainty based on Bayesian deep…

Computer Vision and Pattern Recognition · Computer Science 2018-09-13 Suman Sedai , Bhavna Antony , Dwarikanath Mahapatra , Rahil Garnavi

Optical coherence tomography (OCT) is used for non-invasive diagnosis of diabetic macular edema assessing the retinal layers. In this paper, we propose a new fully convolutional deep architecture, termed ReLayNet, for end-to-end…

Computer Vision and Pattern Recognition · Computer Science 2017-07-10 Abhijit Guha Roy , Sailesh Conjeti , Sri Phani Krishna Karri , Debdoot Sheet , Amin Katouzian , Christian Wachinger , Nassir Navab

Deep learning has been successfully applied to OCT segmentation. However, for data from different manufacturers and imaging protocols, and for different regions of interest (ROIs), it requires laborious and time-consuming data annotation…

Computer Vision and Pattern Recognition · Computer Science 2023-05-09 Haoran Zhang , Jianlong Yang , Ce Zheng , Shiqing Zhao , Aili Zhang

Optical coherence tomography (OCT) is a non-invasive, high-resolution imaging technology that provides cross-sectional images of tissues. Dense acquisition of A-scans along the fast axis is required to obtain high digital resolution images.…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Zezhao Guo , Zhanfang Zhao

Automated drusen segmentation in retinal optical coherence tomography (OCT) scans is relevant for understanding age-related macular degeneration (AMD) risk and progression. This task is usually performed by segmenting the top/bottom…

Image and Video Processing · Electrical Eng. & Systems 2019-07-25 Rhona Asgari , José Ignacio Orlando , Sebastian Waldstein , Ferdinand Schlanitz , Magdalena Baratsits , Ursula Schmidt-Erfurth , Hrvoje Bogunović

The identification and quantification of markers in medical images is critical for diagnosis, prognosis, and disease management. Supervised machine learning enables the detection and exploitation of findings that are known a priori after…

With the introduction of spectral-domain optical coherence tomography (SDOCT), much larger image datasets are routinely acquired compared to what was possible using the previous generation of time-domain OCT. Thus, there is a critical need…

Computer Vision and Pattern Recognition · Computer Science 2015-08-06 Yankui Sun , Tian Zhang , Yue Zhao , Yufan He

Objective: Recognizing retinal vessel abnormity is vital to early diagnosis of ophthalmological diseases and cardiovascular events. However, segmentation results are highly influenced by elusive vessels, especially in low-contrast…

Image and Video Processing · Electrical Eng. & Systems 2019-12-19 Yukun Zhou , Zailiang Chen , Hailan Shen , Xianxian Zheng , Rongchang Zhao , Xuanchu Duan

Segmenting anatomical structures such as the photoreceptor layer in retinal optical coherence tomography (OCT) scans is challenging in pathological scenarios. Supervised deep learning models trained with standard loss functions are usually…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 José Ignacio Orlando , Anna Breger , Hrvoje Bogunović , Sophie Riedl , Bianca S. Gerendas , Martin Ehler , Ursula Schmidt-Erfurth

In medical imaging, the heterogeneity of multi-centre data impedes the applicability of deep learning-based methods and results in significant performance degradation when applying models in an unseen data domain, e.g. a new centreor a new…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 Hongwei Li , Timo Loehr , Anjany Sekuboyina , Jianguo Zhang , Benedikt Wiestler , Bjoern Menze

Organ at risk (OAR) segmentation in computed tomography (CT) imagery is a difficult task for automated segmentation methods and can be crucial for downstream radiation treatment planning. U-net has become a de-facto standard for medical…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Abdullah Nazib , Riad Hassan , Zahidul Islam , Clinton Fookes

We propose a novel model named Multi-Channel Attention Selection Generative Adversarial Network (SelectionGAN) for guided image-to-image translation, where we translate an input image into another while respecting an external semantic…

Computer Vision and Pattern Recognition · Computer Science 2022-10-07 Hao Tang , Philip H. S. Torr , Nicu Sebe