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The ability to modulate brain states using targeted stimulation is increasingly being employed to treat neurological disorders and to enhance human performance. Despite the growing interest in brain stimulation as a form of neuromodulation,…

Neurons and Cognition · Quantitative Biology 2016-01-07 Sarah Feldt Muldoon , Fabio Pasqualetti , Shi Gu , Matthew Cieslak , Scott T. Grafton , Jean M. Vettel , Danielle S. Bassett

Dynamical criticality has been shown to enhance information processing in dynamical systems, and there is evidence for self-organized criticality in neural networks. A plausible mechanism for such self-organization is activity dependent…

Adaptation and Self-Organizing Systems · Physics 2012-09-18 Felix Droste , Anne-Ly Do , Thilo Gross

Neural population activity exhibits complex, nonlinear dynamics, varying in time, over trials, and across experimental conditions. Here, we develop Conditionally Linear Dynamical System (CLDS) models as a general-purpose method to…

Neurons and Cognition · Quantitative Biology 2025-10-31 Victor Geadah , Amin Nejatbakhsh , David Lipshutz , Jonathan W. Pillow , Alex H. Williams

Recently, there have been several concerted international efforts - the BRAIN initiative, European Human Brain Project and the Human Connectome Project, to name a few - that hope to revolutionize our understanding of the connected brain.…

Neurons and Cognition · Quantitative Biology 2016-02-10 Adeel Razi , Karl Friston

A recurrent idea in the study of complex systems is that optimal information processing is to be found near bifurcation points or phase transitions. However, this heuristic hypothesis has few (if any) concrete realizations where a standard…

Neurons and Cognition · Quantitative Biology 2007-05-23 Osame Kinouchi , Mauro Copelli

The critical brain hypothesis states that there are information processing advantages for neuronal networks working close to the critical region of a phase transition. If this is true, we must ask how the networks achieve and maintain this…

Disordered Systems and Neural Networks · Physics 2020-10-22 Osame Kinouchi , Renata Pazzini , Mauro Copelli

This study delves into the plasticity of neural networks, offering empirical support for the notion that critical learning periods and warm-starting performance loss can be avoided through simple adjustments to learning hyperparameters. The…

Machine Learning · Computer Science 2025-10-14 Stanisław Pawlak

The hierarchical organization of the brain is a fundamental structural principle, while brain criticality is a leading hypothesis for its collective dynamics. However, the connection between structure and signatures of criticality remains…

Neurons and Cognition · Quantitative Biology 2026-04-24 Gustavo G. Cambrainha , Daniel M. Castro , Leonardo L. Gollo , Pedro V. Carelli , Mauro Copelli

Previous work showed that the collective activity of large neuronal networks can be tamed to remain near its critical point by a feedback control that maximizes the temporal correlations of the mean-field fluctuations. Since such…

Neurons and Cognition · Quantitative Biology 2023-03-29 Juliane T. Moraes , Eyisto J. Aguilar Trejo , Sabrina Camargo , Silvio C. Ferreira , Dante R. Chialvo

Complex problem solving is a high level cognitive process which has been thoroughly studied over the last decade. The Tower of London (TOL) is a task that has been widely used to study problem-solving. In this study, we aim to explore the…

Neurons and Cognition · Quantitative Biology 2018-10-12 Abdullah Alchihabi , Omer Ekmekci , Baran B. Kivilcim , Sharlene D. Newman , Fatos T. Yarman Vural

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

Machine Learning · Computer Science 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

Signal processing, communications, and control have traditionally relied on classical statistical modeling techniques. Such model-based methods utilize mathematical formulations that represent the underlying physics, prior information and…

Signal Processing · Electrical Eng. & Systems 2022-09-13 Nir Shlezinger , Jay Whang , Yonina C. Eldar , Alexandros G. Dimakis

Pathophysiolpgical modelling of brain systems from microscale to macroscale remains difficult in group comparisons partly because of the infeasibility of modelling the interactions of thousands of neurons at the scales involved. Here, to…

Neurons and Cognition · Quantitative Biology 2026-01-30 Kang You , Gary Green , Jian Zhang

Critical points separate distinct dynamical regimes of complex systems, often delimiting functional or macroscopic phases in which the system operates. However, the long-term prediction of critical regimes and behaviors is challenging given…

Physics and Society · Physics 2025-04-15 Xiangrong Wang , Dan Lu , Zongze Wu , Weina Xu , Hongru Hou , Yanqing Hu , Yamir Moreno

The observation of apparent power-laws in neuronal systems has led to the suggestion that the brain is at, or close to, a critical state and may be a self-organised critical system. Within the framework of self-organised criticality a…

Neurons and Cognition · Quantitative Biology 2014-10-22 Caroline Hartley , Timothy J Taylor , Istvan Z Kiss , Simon F Farmer , Luc Berthouze

Neural networks have emerged as a powerful way to approach many practical problems in quantum physics. In this work, we illustrate the power of deep learning to predict the dynamics of a quantum many-body system, where the training is…

Functional magnetic resonance imaging (fMRI) techniques have contributed significantly to our understanding of brain function. Current methods are based on the analysis of \emph{gradual and continuous} changes in the brain blood oxygenated…

Neurons and Cognition · Quantitative Biology 2011-07-25 Enzo Tagliazucchi , Pablo Balenzuela , Daniel Fraiman , Dante R. Chialvo

Many biological and cognitive systems do not operate deep into one or other regime of activity. Instead, they exploit critical surfaces poised at transitions in their parameter space. The pervasiveness of criticality in natural systems…

Adaptation and Self-Organizing Systems · Physics 2017-02-03 Miguel Aguilera , Manuel G. Bedia

A deep neural network (DNN) that can reliably model muscle responses from corresponding brain stimulation has the potential to increase knowledge of coordinated motor control for numerous basic science and applied use cases. Such cases…

The field of computational modeling of the brain is advancing so rapidly that now it is possible to model large scale networks representing different brain regions with a high level of biological detail in terms of numbers and synapses. For…