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Deep learning methods show promising results for overlapping cervical cell instance segmentation. However, in order to train a model with good generalization ability, voluminous pixel-level annotations are demanded which is quite expensive…

Computer Vision and Pattern Recognition · Computer Science 2020-07-22 Yanning Zhou , Hao Chen , Huangjing Lin , Pheng-Ann Heng

It is generally accepted that one of the critical parts of current vision algorithms based on deep learning and convolutional neural networks is the annotation of a sufficient number of images to achieve competitive performance. This is…

Computer Vision and Pattern Recognition · Computer Science 2021-03-05 Kai Yao , Alberto Ortiz , Francisco Bonnin-Pascual

Cell detection is an essential task in cell image analysis. Recent deep learning-based detection methods have achieved very promising results. In general, these methods require exhaustively annotating the cells in an entire image. If some…

Computer Vision and Pattern Recognition · Computer Science 2021-07-22 Kazuma Fujii , Daiki Suehiro , Kazuya Nishimura , Ryoma Bise

We address the task of weakly-supervised few-shot image classification and segmentation, by leveraging a Vision Transformer (ViT) pretrained with self-supervision. Our proposed method takes token representations from the self-supervised ViT…

Computer Vision and Pattern Recognition · Computer Science 2023-07-10 Dahyun Kang , Piotr Koniusz , Minsu Cho , Naila Murray

Vascular structure segmentation plays a crucial role in medical analysis and clinical applications. The practical adoption of fully supervised segmentation models is impeded by the intricacy and time-consuming nature of annotating vessels…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Zhanqiang Guo , Zimeng Tan , Jianjiang Feng , Jie Zhou

Weakly supervised 3D instance segmentation is essential for 3D scene understanding, especially as the growing scale of data and high annotation costs associated with fully supervised approaches. Existing methods primarily rely on two forms…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Xuexun Liu , Xiaoxu Xu , Qiudan Zhang , Lin Ma , Xu Wang

Annotation-efficient segmentation of the numerous mitochondria instances from various electron microscopy (EM) images is highly valuable for biological and neuroscience research. Although unsupervised domain adaptation (UDA) methods can…

Computer Vision and Pattern Recognition · Computer Science 2026-05-04 Shan Xiong , Jiabao Chen , Ye Wang , Jialin Peng

Live cell culture is crucial in biomedical studies for analyzing cell properties and dynamics in vitro. This study focuses on segmenting unstained live cells imaged with bright-field microscopy. While many segmentation approaches exist for…

Quantitative Methods · Quantitative Biology 2025-08-26 Surajit Das , Gourav Roy , Pavel Zun

Cell detection is the task of detecting the approximate positions of cell centroids from microscopy images. Recently, convolutional neural network-based approaches have achieved promising performance. However, these methods require a…

Computer Vision and Pattern Recognition · Computer Science 2021-07-20 Kazuya Nishimura , Hyeonwoo Cho , Ryoma Bise

Most state-of-the-art instance segmentation methods have to be trained on densely annotated images. While difficult in general, this requirement is especially daunting for biomedical images, where domain expertise is often required for…

Computer Vision and Pattern Recognition · Computer Science 2022-04-05 Adrian Wolny , Qin Yu , Constantin Pape , Anna Kreshuk

Semantic labelling and instance segmentation are two tasks that require particularly costly annotations. Starting from weak supervision in the form of bounding box detection annotations, we propose a new approach that does not require…

Computer Vision and Pattern Recognition · Computer Science 2016-11-24 Anna Khoreva , Rodrigo Benenson , Jan Hosang , Matthias Hein , Bernt Schiele

Detecting and segmenting individual cells from microscopy images is critical to various life science applications. Traditional cell segmentation tools are often ill-suited for applications in brightfield microscopy due to poor contrast and…

Image and Video Processing · Electrical Eng. & Systems 2020-05-20 Rituparna Sarkar , Suvadip Mukherjee , Elisabeth Labruyère , Jean-Christophe Olivo-Marin

Accurate identification of breast masses is crucial in diagnosing breast cancer; however, it can be challenging due to their small size and being camouflaged in surrounding normal glands. Worse still, it is also expensive in clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Xinyu Xiong , Churan Wang , Wenxue Li , Guanbin Li

Training machine learning models to segment tumors and other anomalies in medical images is an important step for developing diagnostic tools but generally requires manually annotated ground truth segmentations, which necessitates…

Computer Vision and Pattern Recognition · Computer Science 2024-01-24 Jay J. Yoo , Khashayar Namdar , Farzad Khalvati

We tackle biomedical image segmentation in the scenario of only a few labeled brain MR images. This is an important and challenging task in medical applications, where manual annotations are time-consuming. Current multi-atlas based…

Computer Vision and Pattern Recognition · Computer Science 2020-01-14 Hyeon Woo Lee , Mert R. Sabuncu , Adrian V. Dalca

Microscopy imaging techniques are instrumental for characterization and analysis of biological structures. As these techniques typically render 3D visualization of cells by stacking 2D projections, issues such as out-of-plane excitation and…

Image and Video Processing · Electrical Eng. & Systems 2023-02-16 Amirkoushyar Ziabari , Derek C. Rose , Abbas Shirinifard , David Solecki

Weakly supervised segmentation methods using bounding box annotations focus on obtaining a pixel-level mask from each box containing an object. Existing methods typically depend on a class-agnostic mask generator, which operates on the…

Computer Vision and Pattern Recognition · Computer Science 2021-03-17 Jungbeom Lee , Jihun Yi , Chaehun Shin , Sungroh Yoon

Since the preparation of labeled data for training semantic segmentation networks of point clouds is a time-consuming process, weakly supervised approaches have been introduced to learn from only a small fraction of data. These methods are…

Computer Vision and Pattern Recognition · Computer Science 2022-09-16 Gengxin Liu , Oliver van Kaick , Hui Huang , Ruizhen Hu

Annotation is a major hurdle in the semantic segmentation of microscopy images and volumes due to its prerequisite expertise and effort. This work enables the training of semantic segmentation networks on images with only a single point for…

Computer Vision and Pattern Recognition · Computer Science 2021-03-22 Shijie Li , Neel Dey , Katharina Bermond , Leon von der Emde , Christine A. Curcio , Thomas Ach , Guido Gerig

It is laborious to manually label point cloud data for training high-quality 3D object detectors. This work proposes a weakly supervised approach for 3D object detection, only requiring a small set of weakly annotated scenes, associated…

Computer Vision and Pattern Recognition · Computer Science 2020-07-24 Qinghao Meng , Wenguan Wang , Tianfei Zhou , Jianbing Shen , Luc Van Gool , Dengxin Dai