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The collective action of actively contractile units embedded in elastic biopolymer networks plays a crucial role in regulating the network's macroscopic mechanical response. Here, we investigate how the macroscopic boundary stress in model…

Soft Condensed Matter · Physics 2026-03-25 Abhinav Kumar , David A. Quint , Kinjal Dasbiswas

In biological systems, molecular-scale forces and motions are pivotal for enabling processes like motility, shape change, and replication. These forces and motions are organized, amplified, and transmitted across macroscopic scales by…

Highly-deformable materials, from synthetic hydrogels to biological tissues, are becoming increasingly important from both fundamental and practical perspectives. Their mechanical behaviors, in particular the dynamics of crack propagation…

Materials Science · Physics 2015-06-09 Tamar Goldman Boué , Roi Harpaz , Jay Fineberg , Eran Bouchbinder

The actin cytoskeleton in living cells generates forces in conjunction with myosin motor proteins to directly and indirectly drive essential cellular processes. The semiflexible filaments of the cytoskeleton can respond nonlinearly to the…

Soft Condensed Matter · Physics 2019-12-19 D. Mizuno , C. Tardin , C. F. Schmidt

The mechanical properties of the cell depend crucially on the tension of its cytoskeleton, a biopolymer network that is put under stress by active motor proteins. While the fibrous nature of the network is known to strongly affect the…

Soft Condensed Matter · Physics 2018-05-15 Pierre Ronceray , Chase P. Broedersz , Martin Lenz

When tensioned, ordinary materials expand along the direction of the applied force. Here, we explore network concepts to design metamaterials exhibiting negative compressibility transitions, during which a material undergoes contraction…

Materials Science · Physics 2012-07-11 Zachary G. Nicolaou , Adilson E. Motter

Animal cells in tissues are supported by biopolymer matrices, which typically exhibit highly nonlinear mechanical properties. While the linear elasticity of the matrix can significantly impact cell mechanics and functionality, it remains…

Fiber-reinforcement is a universal feature of many biological tissues. It involves the interplay between fiber stiffness, fiber orientation, and the elastic properties of the matrix, influencing pattern formation and evolution in layered…

Soft Condensed Matter · Physics 2025-04-29 Yang Liu , Rui-Cheng Liu , Wanyu Ma , Alain Goriely

Manipulating topological disclination networks that arise in a symmetry-breaking phase transfor- mation in widely varied systems including anisotropic materials can potentially lead to the design of novel materials like conductive…

Soft Condensed Matter · Physics 2017-12-19 Amit Kumar Bhattacharjee

The shapes of epithelial tissues result from a complex interplay of contractile forces in the cytoskeleta of the cells in the tissue, and adhesion forces between them. A host of discrete, cell-based models describe these forces by assigning…

Soft Condensed Matter · Physics 2019-02-27 Pierra A. Haas , Raymond E. Goldstein

Stress patterns in static granular media exhibit unusual features when compared to either liquids or elastic solids. Qualitatively, we attribute these features to the presence of `stress paths', whose geometry depends on the construction…

Condensed Matter · Physics 2007-05-23 J. -P. Bouchaud , P. Claudin , M. E. Cates , J. P. Wittmer

Biological cells embedded in fibrous matrices have been observed to form inter-cellular bands of dense and aligned fibers, through which they mechanically interact over long distances. Such matrix-mediated cellular interactions have been…

Biological Physics · Physics 2018-11-14 Ran S Sopher , Hanan Tokash , Sari Natan , Mirit Sharabi , Ortal Shelah , Oren Tchaicheeyan , Ayelet Lesman

Experiments on isotropic compression of a granular assembly of spheres show that the shear and bulk moduli vary with the confining pressure faster than the 1/3 power law predicted by Hertz-Mindlin effective medium theories (EMT) of contact…

Soft Condensed Matter · Physics 2009-11-11 Hernan A. Makse , Nicolas Gland , David L. Johnson , Lawrence Schwartz

Cell proliferation, apoptosis, and myosin-dependent contraction can generate elastic stress and strain in living tissues, which may be dissipated by internal rearrangement through cell topological transition and cytoskeletal reorganization.…

Biological Physics · Physics 2021-12-07 Chaozhen Wei , Min Wu

The buckling of a soft elastic sample under growth or swelling has highlighted a new interest in materials science, morphogenesis, and biology or physiology. Indeed, the change of mass or volume is a common fact of any living species, and…

Soft Condensed Matter · Physics 2023-09-21 Martine Ben Amar

This paper investigates the effects of plasticity on the effective fracture toughness. A layered material is considered as a modelling system. An elastic-plastic phase-field model and a surfing boundary condition are used to study how the…

Computational Engineering, Finance, and Science · Computer Science 2020-10-15 Stella Brach

Mechanical forces generated by myosin II molecular motors drive diverse cellular processes, most notably shape change, division and locomotion. These forces may be transmitted over long range through the cytoskeletal medium - a disordered,…

Soft Condensed Matter · Physics 2023-02-28 Abhinav Kumar , David A. Quint , Kinjal Dasbiswas

Collagen is the main structural and load-bearing element of various connective tissues, where it forms the extracellular matrix that supports cells. It has long been known that collagenous tissues exhibit a highly nonlinear stress-strain…

We experimentally study linear and nonlinear waves on the surface of a fluid covered by an elastic sheet where both tension and flexural waves take place. An optical method is used to obtain the full space-time wave field, and the…

Fluid Dynamics · Physics 2014-02-10 Luc Deike , Jean-Claude Bacri , Eric Falcon

Disordered soft materials, such as fibrous networks in biological contexts exhibit a nonlinear elastic response. We study such nonlinear behavior with a minimal model for networks on lattice geometries with simple Hookian elements with…

Soft Condensed Matter · Physics 2015-03-13 M. Sheinman , C. P. Broedersz , F. C. MacKintosh