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Machine learning models have had discernible achievements in a myriad of applications. However, most of these models are black-boxes, and it is obscure how the decisions are made by them. This makes the models unreliable and untrustworthy.…

Machine Learning · Computer Science 2020-03-23 Raha Moraffah , Mansooreh Karami , Ruocheng Guo , Adrienne Raglin , Huan Liu

One of the desired key properties of deep learning models is the ability to generalise to unseen samples. When provided with new samples that are (perceptually) similar to one or more training samples, deep learning models are expected to…

Sound · Computer Science 2025-08-07 Katharina Hoedt , Arthur Flexer , Gerhard Widmer

Electronic Health Records have become popular sources of data for secondary research, but their use is hampered by the amount of effort it takes to overcome the sparsity, irregularity, and noise that they contain. Modern learning…

Applications · Statistics 2025-02-28 Jacek M. Bajor , Diego A. Mesa , Travis J. Osterman , Thomas A. Lasko

Machine-learning models are ubiquitous. In some domains, for instance, in medicine, the models' predictions must be interpretable. Decision trees, classification rules, and subgroup discovery are three broad categories of supervised…

Machine Learning · Computer Science 2022-04-29 Vadim Arzamasov , Benjamin Jochum , Klemens Böhm

Machine Learning (ML) models are often complex and difficult to interpret due to their 'black-box' characteristics. Interpretability of a ML model is usually defined as the degree to which a human can understand the cause of decisions…

Methodology · Statistics 2020-06-25 Simon Kocbek , Primoz Kocbek , Leona Cilar , Gregor Stiglic

The interpretability of ML models is important, but it is not clear what it amounts to. So far, most philosophers have discussed the lack of interpretability of black-box models such as neural networks, and methods such as explainable AI…

Machine Learning · Computer Science 2024-01-05 Tim Räz

For machine learning models to be most useful in numerous sociotechnical systems, many have argued that they must be human-interpretable. However, despite increasing interest in interpretability, there remains no firm consensus on how to…

Machine Learning · Computer Science 2021-02-03 Andrew Slavin Ross , Nina Chen , Elisa Zhao Hang , Elena L. Glassman , Finale Doshi-Velez

Machine Learning (ML) algorithms are vital for supporting clinical decision-making in biomedical informatics. However, their predictive performance can vary across demographic groups, often due to the underrepresentation of historically…

Machine Learning · Computer Science 2025-03-04 Ioannis Bilionis , Ricardo C. Berrios , Luis Fernandez-Luque , Carlos Castillo

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

Machine learning (ML) has seen significant growth in both popularity and importance. The high prediction accuracy of ML models is often achieved through complex black-box architectures that are difficult to interpret. This interpretability…

Machine Learning · Statistics 2024-07-29 David Köhler , David Rügamer , Matthias Schmid

The last decade has seen huge progress in the development of advanced machine learning models; however, those models are powerless unless human users can interpret them. Here we show how the mind's construction of concepts and meaning can…

Machine Learning · Statistics 2016-07-04 Nick Condry

Building accurate and interpretable Machine Learning (ML) models for heterogeneous/mixed data is a long-standing challenge for algorithms designed for numeric data. This work focuses on developing numeric coding schemes for non-numeric…

Machine Learning · Computer Science 2023-11-27 Boris Kovalerchuk , Elijah McCoy

Artificial Intelligence (AI) and its data-centric branch of machine learning (ML) have greatly evolved over the last few decades. However, as AI is used increasingly in real world use cases, the importance of the interpretability of and…

Machine Learning · Computer Science 2022-12-01 N. Ranasinghe , A. Ramanan , S. Fernando , P. N. Hameed , D. Herath , T. Malepathirana , P. Suganthan , M. Niranjan , S. Halgamuge

Estimating causal effect using machine learning (ML) algorithms can help to relax functional form assumptions if used within appropriate frameworks. However, most of these frameworks assume settings with cross-sectional data, whereas…

Econometrics · Economics 2024-09-04 Jonathan Fuhr , Dominik Papies

Class imbalance poses a significant challenge in classification tasks, where traditional approaches often lead to biased models and unreliable predictions. Undersampling and oversampling techniques have been commonly employed to address…

Machine Learning · Computer Science 2025-10-22 Matt Clifford , Jonathan Erskine , Alexander Hepburn , Raúl Santos-Rodríguez , Dario Garcia-Garcia

Modern time series forecasting increasingly relies on complex ensemble models generated by AutoML systems like AutoGluon, delivering superior accuracy but with significant costs to transparency and interpretability. This paper introduces a…

Machine Learning · Computer Science 2025-10-13 Yikai Zhao , Jiekai Ma

In this review, we examine the problem of designing interpretable and explainable machine learning models. Interpretability and explainability lie at the core of many machine learning and statistical applications in medicine, economics,…

Machine Learning · Computer Science 2023-03-02 Ričards Marcinkevičs , Julia E. Vogt

Machine Learning has been applied to pathology images in research and clinical practice with promising outcomes. However, standard ML models often lack the rigorous evaluation required for clinical decisions. Machine learning techniques for…

Image and Video Processing · Electrical Eng. & Systems 2022-04-19 Syed Ashar Javed , Dinkar Juyal , Zahil Shanis , Shreya Chakraborty , Harsha Pokkalla , Aaditya Prakash

We introduce Matched Machine Learning, a framework that combines the flexibility of machine learning black boxes with the interpretability of matching, a longstanding tool in observational causal inference. Interpretability is paramount in…

Methodology · Statistics 2023-04-05 Marco Morucci , Cynthia Rudin , Alexander Volfovsky

An interpretable machine learning (ML) framework is introduced to enhance the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) by ensuring robustness of the ML models' interpretations. The dataset used comprises…