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Fueled by breakthrough technology developments, the biological, biomedical, and behavioral sciences are now collecting more data than ever before. There is a critical need for time- and cost-efficient strategies to analyze and interpret…

Explainability techniques for data-driven predictive models based on artificial intelligence and machine learning algorithms allow us to better understand the operation of such systems and help to hold them accountable. New transparency…

Machine Learning · Computer Science 2022-09-09 Kacper Sokol , Alexander Hepburn , Raul Santos-Rodriguez , Peter Flach

When predictive models are used to support complex and important decisions, the ability to explain a model's reasoning can increase trust, expose hidden biases, and reduce vulnerability to adversarial attacks. However, attempts at…

Machine Learning · Computer Science 2019-07-11 Dimitris Bertsimas , Arthur Delarue , Patrick Jaillet , Sebastien Martin

An increasing number of model-agnostic interpretation techniques for machine learning (ML) models such as partial dependence plots (PDP), permutation feature importance (PFI) and Shapley values provide insightful model interpretations, but…

Machine learning (ML) and deep learning models are extensively used for parameter optimization and regression problems. However, not all inverse problems in ML are ``identifiable,'' indicating that model parameters may not be uniquely…

Machine Learning · Computer Science 2023-07-24 Reza Sameni

The escalating integration of machine learning in high-stakes fields such as healthcare raises substantial concerns about model fairness. We propose an interpretable framework - Fairness-Aware Interpretable Modeling (FAIM), to improve model…

Machine Learning · Computer Science 2024-03-11 Mingxuan Liu , Yilin Ning , Yuhe Ke , Yuqing Shang , Bibhas Chakraborty , Marcus Eng Hock Ong , Roger Vaughan , Nan Liu

Causal relationships play a pivotal role in research within the field of public administration. Ensuring reliable causal inference requires validating the predictability of these relationships, which is a crucial precondition. However,…

Computers and Society · Computer Science 2026-01-13 Zhanyu Liu , Yang Yu

In modern business processes, the amount of data collected has increased substantially in recent years. Because this data can potentially yield valuable insights, automated knowledge extraction based on process mining has been proposed,…

Machine Learning · Computer Science 2022-12-02 Riza Velioglu , Jan Philip Göpfert , André Artelt , Barbara Hammer

In the context of image classification, Concept Bottleneck Models (CBMs) first embed images into a set of human-understandable concepts, followed by an intrinsically interpretable classifier that predicts labels based on these intermediate…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Haifei Zhang , Patrick Barry , Eduardo Brandao

Interpretability in machine learning models is important in high-stakes decisions, such as whether to order a biopsy based on a mammographic exam. Mammography poses important challenges that are not present in other computer vision tasks:…

Machine Learning · Computer Science 2021-03-24 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

Predictive Business Process Monitoring (PBPM) aims to forecast future outcomes of ongoing business processes. However, existing methods often lack flexibility to handle real-world challenges such as simultaneous events, class imbalance, and…

Machine Learning · Computer Science 2025-08-06 Fang Wang , Paolo Ceravolo , Ernesto Damiani

Modern predictive analytics underpinned by machine learning techniques has become a key enabler to the automation of data-driven decision making. In the context of business process management, predictive analytics has been applied to making…

Machine Learning · Computer Science 2020-06-09 Renuka Sindhgatta , Chun Ouyang , Catarina Moreira

Building generalizable AI models is one of the primary challenges in the healthcare domain. While radiologists rely on generalizable descriptive rules of abnormality, Neural Network (NN) models suffer even with a slight shift in input…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Shantanu Ghosh , Ke Yu , Kayhan Batmanghelich

One challenging property lurking in medical datasets is the imbalanced data distribution, where the frequency of the samples between the different classes is not balanced. Training a model on an imbalanced dataset can introduce unique…

Image and Video Processing · Electrical Eng. & Systems 2022-04-06 Ashkan Khakzar , Yawei Li , Yang Zhang , Mirac Sanisoglu , Seong Tae Kim , Mina Rezaei , Bernd Bischl , Nassir Navab

Building on existing work with Hyperblocks, which classify data using minimum and maximum bounds for each attribute, we focus on enhancing interpretability, decreasing training time, and reducing model complexity without sacrificing…

Machine Learning · Computer Science 2025-06-10 Austin Snyder , Ryan Gallagher , Boris Kovalerchuk

In Explainable AI, rule extraction translates model knowledge into logical rules, such as IF-THEN statements, crucial for understanding patterns learned by black-box models. This could significantly aid in fields like disease diagnosis,…

Machine Learning · Computer Science 2024-08-16 Yu Chen , Tianyu Cui , Alexander Capstick , Nan Fletcher-Loyd , Payam Barnaghi

Automated Machine Learning-based systems' integration into a wide range of tasks has expanded as a result of their performance and speed. Although there are numerous advantages to employing ML-based systems, if they are not interpretable,…

Machine Learning · Computer Science 2022-12-08 Ioannis Mollas , Nick Bassiliades , Grigorios Tsoumakas

High-stakes applications require AI-generated models to be interpretable. Current algorithms for the synthesis of potentially interpretable models rely on objectives or regularization terms that represent interpretability only coarsely…

Machine Learning · Computer Science 2021-04-28 Marco Virgolin , Andrea De Lorenzo , Francesca Randone , Eric Medvet , Mattias Wahde

Machine learning algorithms often assume that training samples are independent. When data points are connected by a network, the induced dependency between samples is both a challenge, reducing effective sample size, and an opportunity to…

Machine Learning · Statistics 2025-09-22 Tiffany M. Tang , Elizaveta Levina , Ji Zhu

An active challenge in developing multimodal machine learning (ML) models for healthcare is handling missing modalities during training and deployment. As clinical datasets are inherently temporal and sparse in terms of modality presence,…

Machine Learning · Computer Science 2026-05-08 Andrew Wang , Ellie Pavlick , Ritambhara Singh
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