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Nanopore genome sequencing is the key to enabling personalized medicine, global food security, and virus surveillance. The state-of-the-art base-callers adopt deep neural networks (DNNs) to translate electrical signals generated by nanopore…

Hardware Architecture · Computer Science 2020-08-10 Qian Lou , Sarath Janga , Lei Jiang

This article introduces HODLR3D, a class of hierarchical matrices arising out of $N$-body problems in three dimensions. HODLR3D relies on the fact that certain off-diagonal matrix sub-blocks arising out of the $N$-body problems in three…

Numerical Analysis · Mathematics 2023-08-01 V A Kandappan , Vaishnavi Gujjula , Sivaram Ambikasaran

Topology optimization (TO) has been widely adopted in engineering design; however, it is prone to being trapped in local optima, particularly in strongly nonlinear problems. Sensitivity-free data-driven topology design (DDTD) offers a…

Computational Physics · Physics 2026-03-10 Jun Yang , Ziliang Wang , Shintaro Yamasaki

Edge inference techniques partition and distribute Deep Neural Network (DNN) inference tasks among multiple edge nodes for low latency inference, without considering the core-level heterogeneity of edge nodes. Further, default DNN inference…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-11-26 Zain Taufique , Aman Vyas , Antonio Miele , Pasi Liljeberg , Anil Kanduri

We consider the problem of high-dimensional non-linear variable selection for supervised learning. Our approach is based on performing linear selection among exponentially many appropriately defined positive definite kernels that…

Machine Learning · Computer Science 2009-09-08 Francis Bach

Hierarchical ring networks, which hierarchically connect multiple levels of rings, have been proposed in the past to improve the scalability of ring interconnects, but past hierarchical ring designs sacrifice some of the key benefits of…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-02-22 Rachata Ausavarungnirun , Chris Fallin , Xiangyao Yu , Kevin Kai-Wei Chang , Greg Nazario , Reetuparna Das , Gabriel H. Loh , Onur Mutlu

Hierarchical and complex Mathematical Expression Recognition (MER) is challenging due to multiple possible interpretations of a formula, complicating both parsing and evaluation. In this paper, we introduce the Hierarchical Detail-Focused…

Computation and Language · Computer Science 2025-01-10 Jiale Wang , Junhui Yu , Huanyong Liu , Chenanran Kong

This paper establishes a kernel-based framework for reconstructing data on manifolds, tailored to fit the dynamic-(d)MRI-data recovery problem. The proposed methodology exploits simple tangent-space geometries of manifolds in reproducing…

Machine Learning · Computer Science 2020-02-28 Gaurav N. Shetty , Konstantinos Slavakis , Ukash Nakarmi , Gesualdo Scutari , Leslie Ying

Kernel-based methods offer a powerful and flexible mathematical framework for addressing histopolation problems. In histopolation, the available input data does not consist of pointwise function samples but of averages taken over intervals…

Numerical Analysis · Mathematics 2026-01-14 Ludovico Bruni Bruno , Giacomo Cappellazzo , Wolfgang Erb , Mohammad Karimnejad Esfahani

The data-driven computing paradigm initially introduced by Kirchdoerfer and Ortiz (2016) enables finite element computations in solid mechanics to be performed directly from material data sets, without an explicit material model. From a…

Computational Engineering, Finance, and Science · Computer Science 2021-05-19 Robert Eggersmann , Laurent Stainier , Michael Ortiz , Stefanie Reese

We consider a fast, data-sparse directional method to realize matrix-vector products related to point evaluations of the Helmholtz kernel. The method is based on a hierarchical partitioning of the point sets and the matrix. The considered…

Numerical Analysis · Mathematics 2021-01-08 Günther Of , Raphael Watschinger

This paper describes a hierarchical learning strategy for generating sparse representations of multivariate datasets. The hierarchy arises from approximation spaces considered at successively finer scales. A detailed analysis of stability,…

Machine Learning · Statistics 2019-10-23 Prashant Shekhar , Abani Patra

Dialogue policy training for composite tasks, such as restaurant reservation in multiple places, is a practically important and challenging problem. Recently, hierarchical deep reinforcement learning (HDRL) methods have achieved good…

Computation and Language · Computer Science 2020-09-23 Zhi Chen , Xiaoyuan Liu , Lu Chen , Kai Yu

Submodular function maximization is a critical building block for diverse tasks, such as document summarization, sensor placement, and image segmentation. Yet its practical utility is often limit by the $O(knd^2)$ computational bottleneck.…

Machine Learning · Computer Science 2026-01-29 Boyu Liu , Lianke Qin , Zhao Song , Yitan Wang , Jiale Zhao

In this paper, we address the problem of privacy-preserving federated neural network training with $N$ users. We present Hercules, an efficient and high-precision training framework that can tolerate collusion of up to $N-1$ users. Hercules…

Cryptography and Security · Computer Science 2022-07-12 Guowen Xu , Xingshuo Han , Shengmin Xu , Tianwei Zhang , Hongwei Li , Xinyi Huang , Robert H. Deng

Mining frequent itemsets from massive datasets is always being a most important problem of data mining. Apriori is the most popular and simplest algorithm for frequent itemset mining. To enhance the efficiency and scalability of Apriori, a…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-11-24 Sudhakar Singh , Rakhi Garg , P. K. Mishra

We introduce a novel data-driven order reduction method for nonlinear control systems, drawing on recent progress in machine learning and statistical dimensionality reduction. The method rests on the assumption that the nonlinear system…

Optimization and Control · Mathematics 2011-06-15 Jake Bouvrie , Boumediene Hamzi

High-throughput chromatin conformation capture (Hi-C) data provide insights into the 3D structure of chromosomes, with normalization being a crucial pre-processing step. A common technique for normalization is matrix balancing, which…

Applications · Statistics 2025-06-17 John Park , Ning Hao , Yue Selena Niu , Ming Hu

We introduce the Hierarchically Interacting Particle Neural Network (HIP-NN) to model molecular properties from datasets of quantum calculations. Inspired by a many-body expansion, HIP-NN decomposes properties, such as energy, as a sum over…

Machine Learning · Statistics 2018-04-04 Nicholas Lubbers , Justin S. Smith , Kipton Barros

Handling incomplete and heterogeneous data remains a central challenge in real-world machine learning, where missing values may follow complex mechanisms (MCAR, MAR, MNAR) and features can be of mixed types (numerical and categorical).…

Machine Learning · Computer Science 2025-07-30 Youran Zhou , Mohamed Reda Bouadjenek , Jonathan Wells , Sunil Aryal
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