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We set up a rigorous thermodynamic description of reaction-diffusion systems driven out of equilibrium by time-dependent space-distributed chemostats. Building on the assumption of local equilibrium, nonequilibrium thermodynamic potentials…

Statistical Mechanics · Physics 2018-09-12 Gianmaria Falasco , Riccardo Rao , Massimiliano Esposito

Turing's theory of pattern formation has been used to describe the formation of self-organised periodic patterns in many biological, chemical and physical systems. However, the use of such models is hindered by our inability to predict, in…

Pattern Formation and Solitons · Physics 2021-02-03 Srikanth Subramanian , Sean M. Murray

Self-organization, the ability of a system of microscopically interacting entities to shape macroscopically ordered structures, is ubiquitous in Nature. Spatio-temporal patterns are abundantly observed in a large plethora of applications,…

Pattern Formation and Solitons · Physics 2019-06-17 Malbor Asllani , Timoteo Carletti , Duccio Fanelli , Philip K. Maini

Alan Turing's work in Morphogenesis has received wide attention during the past 60 years. The central idea behind his theory is that two chemically interacting diffusible substances are able to generate stable spatial patterns, provided…

Quantitative Methods · Quantitative Biology 2014-07-29 Tatiana T. Marquez-Lago , Pablo Padilla

Spontaneous pattern formation is a fundamental scientific problem that has received much attention since the seminal theoretical work of Turing on reaction-diffusion systems. In molecular biophysics, this phenomena often takes place under…

Statistical Mechanics · Physics 2020-11-17 Shubhashis Rana , Andre C Barato

Spontaneous pattern formation in homogeneous systems is ubiquitous in nature. Although Turing demonstrated that spatial patterns can emerge in reaction-diffusion (RD) systems when the homogeneous state becomes linearly unstable, it remains…

Biological Physics · Physics 2024-08-20 Shuonan Wu , Bing Yu , Yuhai Tu , Lei Zhang

Reaction-diffusion (Turing) systems are fundamental to the formation of spatial patterns in nature and engineering. These systems are governed by a set of non-linear partial differential equations containing parameters that determine the…

Machine Learning · Computer Science 2022-11-28 Jordon Kho , Winston Koh , Jian Cheng Wong , Pao-Hsiung Chiu , Chin Chun Ooi

Patterns are ubiquitous in nature, but how they form is often unclear. Turing developed a seminal theory to explain patterns based on reactions that counteract the equalizing tendency of diffusion. These reactions require continuous energy…

Biological Physics · Physics 2025-11-24 Cathelijne ter Burg , David Zwicker

We develop a framework describing the dynamics and thermodynamics of open non-ideal reaction-diffusion systems, which embodies Flory-Huggins theories of mixtures and chemical reaction network theories. Our theory elucidates the mechanisms…

Molecular Networks · Quantitative Biology 2024-12-05 Francesco Avanzini , Timur Aslyamov , Étienne Fodor , Massimiliano Esposito

Originating from the pioneering study of Alan Turing, the bifurcation analysis predicting spatial pattern formation from a spatially uniform state for diffusing morphogens or chemical species that interact through nonlinear reactions is a…

Pattern Formation and Solitons · Physics 2023-01-18 Merlin Pelz , Michael J. Ward

Long after Turing's seminal Reaction-Diffusion (RD) model, the elegance of his fundamental equations alleviated much of the skepticism surrounding pattern formation. Though Turing model is a simplification and an idealization, it is one of…

Machine Learning · Computer Science 2020-12-09 Litu Rout

We establish universal relations between pattern formation and dissipation with a geometric approach to nonequilibrium thermodynamics of deterministic reaction-diffusion systems. We first provide a way to systematically decompose the…

Statistical Mechanics · Physics 2026-05-04 Ryuna Nagayama , Kohei Yoshimura , Artemy Kolchinsky , Sosuke Ito

The study of pattern-forming instabilities in reaction-diffusion systems on growing or otherwise time-dependent domains arises in a variety of settings, including applications in developmental biology, spatial ecology, and experimental…

Pattern Formation and Solitons · Physics 2022-07-11 Robert A. Van Gorder , Václav Klika , Andrew L. Krause

The diffusion-driven Turing instability is a potential mechanism for spatial pattern formation in numerous biological and chemical systems. However, engineering these patterns and demonstrating that they are produced by this mechanism is…

Biological Physics · Physics 2025-12-02 Antonio Matas-Gil , Robert G. Endres

Active matter generates order or patterns through nonequilibrium dynamics. An open research challenge is to determine how efficiently a nonequilibrium self-organising system can convert consumed energy into macroscopic order. We study an…

Adaptation and Self-Organizing Systems · Physics 2026-05-07 Qianyang Chen , Mikhail Prokopenko

Turing theory of pattern formation is among the most popular theoretical means to account for the variety of spatio-temporal structures observed in Nature and, for this reason, finds applications in many different fields. While Turing…

Pattern Formation and Solitons · Physics 2025-10-22 Riccardo Muolo , Luca Gallo , Vito Latora , Mattia Frasca , Timoteo Carletti

Intracellular protein patterns govern essential cellular functions by dynamically redistributing proteins between membrane-bound and cytosolic states, conserving their total numbers. This review presents a theoretical framework for…

Biological Physics · Physics 2025-12-16 Erwin Frey , Henrik Weyer

In the nearly seven decades since the publication of Alan Turing's work on morphogenesis, enormous progress has been made in understanding both the mathematical and biological aspects of his proposed reaction-diffusion theory. Some of these…

Pattern Formation and Solitons · Physics 2021-12-01 Andrew L. Krause , Eamonn A. Gaffney , Philip K. Maini , Václav Klika

As proposed by Alan Turing in 1952 as a ubiquitous mechanism for nonequilibrium pattern formation, diffusional effects may destabilize uniform distributions of reacting chemical species and lead to both spatially and temporally…

Pattern Formation and Solitons · Physics 2013-10-28 Shigefumi Hata , Hiroya Nakao , Alexander S. Mikhailov

Turing patterns are a central paradigm for describing spatial patterns in nature. The corresponding theory of reaction-diffusion dynamics combines ideal diffusion with nonlinear reactions, resulting in patterns when species diffuse at…

Biological Physics · Physics 2026-01-28 Cathelijne ter Burg , David Zwicker
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