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Ongoing studies have identified similarities between neural representations in biological networks and in deep artificial neural networks. This has led to renewed interest in developing analogies between the backpropagation learning…

Neural and Evolutionary Computing · Computer Science 2019-06-11 Theodore H. Moskovitz , Ashok Litwin-Kumar , L. F. Abbott

The development of biologically-plausible learning algorithms is important for understanding learning in the brain, but most of them fail to scale-up to real-world tasks, limiting their potential as explanations for learning by real brains.…

Neural and Evolutionary Computing · Computer Science 2022-02-01 Maxence Ernoult , Fabrice Normandin , Abhinav Moudgil , Sean Spinney , Eugene Belilovsky , Irina Rish , Blake Richards , Yoshua Bengio

We propose a solution to the weight transport problem, which questions the biological plausibility of the backpropagation algorithm. We derive our method based upon a theoretical analysis of the (approximate) dynamics of leaky…

Neurons and Cognition · Quantitative Biology 2021-08-12 Nasir Ahmad , Luca Ambrogioni , Marcel A. J. van Gerven

In timing-based neural codes, neurons have to emit action potentials at precise moments in time. We use a supervised learning paradigm to derive a synaptic update rule that optimizes via gradient ascent the likelihood of postsynaptic firing…

Neurons and Cognition · Quantitative Biology 2007-05-23 Jean-Pascal Pfister , Taro Toyoizumi , David Barber , Wulfram Gerstner

Stochastic gradient descent with backpropagation is the workhorse of artificial neural networks. It has long been recognized that backpropagation fails to be a biologically plausible algorithm. Fundamentally, it is a non-local procedure --…

Machine Learning · Statistics 2021-12-24 Ganlin Song , Ruitu Xu , John Lafferty

Optimization algorithms are fundamental to modern deep learning, yet most widely used methods rely on update rules based primarily on local gradient statistics. We introduce NeuroPlastic, a plasticity-modulated optimizer that augments…

Machine Learning · Computer Science 2026-04-30 Douglas Jiang , Yuechen Wang , Jiayi Wang , Jiaying Geng , Qinglong Wang , Feng Tian

The Resilient Propagation (Rprop) algorithm has been very popular for backpropagation training of multilayer feed-forward neural networks in various applications. The standard Rprop however encounters difficulties in the context of deep…

Neural and Evolutionary Computing · Computer Science 2015-09-17 Alan Mosca , George D. Magoulas

Nearly all state-of-the-art deep learning algorithms rely on error backpropagation, which is generally regarded as biologically implausible. An alternative way of training an artificial neural network is through treating each unit in the…

Machine Learning · Computer Science 2021-10-06 Stephen Chung

In this survey, we examine algorithms for conducting credit assignment in artificial neural networks that are inspired or motivated by neurobiology. These processes are unified under one possible taxonomy, which is constructed based on how…

Neural and Evolutionary Computing · Computer Science 2023-12-27 Alexander G. Ororbia

Since humans still outperform artificial neural networks on many tasks, drawing inspiration from the brain may help to improve current machine learning algorithms. Contrastive Hebbian Learning (CHL) and Equilibrium Propagation (EP) are…

Neural and Evolutionary Computing · Computer Science 2022-05-02 Yoshimasa Kubo , Eric Chalmers , Artur Luczak

Empowered by the backpropagation (BP) algorithm, deep neural networks have dominated the race in solving various cognitive tasks. The restricted training pattern in the standard BP requires end-to-end error propagation, causing large memory…

Machine Learning · Computer Science 2022-05-17 Wenzhe Guo , Mohammed E Fouda , Ahmed M. Eltawil , Khaled N. Salama

Computational neuroscience relies on large-scale dynamical-systems models of neurons, with a vast amount of offline, pre-simulation, tuned parameters, with models often tied to their brain simulators. These fixed parameters lead to stiff…

Neurons and Cognition · Quantitative Biology 2025-12-25 Lennart P. L. Landsmeer , Mario Negrello , Said Hamdioui , Christos Strydis

An ongoing challenge in neuromorphic computing is to devise general and computationally efficient models of inference and learning which are compatible with the spatial and temporal constraints of the brain. One increasingly popular and…

Neural and Evolutionary Computing · Computer Science 2019-05-06 Emre Neftci , Charles Augustine , Somnath Paul , Georgios Detorakis

Equilibrium Propagation (EP) is a biologically inspired alternative algorithm to backpropagation (BP) for training neural networks. It applies to RNNs fed by a static input x that settle to a steady state, such as Hopfield networks. EP is…

Neural and Evolutionary Computing · Computer Science 2020-05-11 Maxence Ernoult , Julie Grollier , Damien Querlioz , Yoshua Bengio , Benjamin Scellier

Precise control of signal propagation in modular neural networks represents a fundamental challenge in computational neuroscience. We establish a framework for identifying optimal control nodes that maximize stimulus transmission between…

Neurons and Cognition · Quantitative Biology 2025-08-18 Bulat Batuev , Arsenii Onuchin , Sergey Sukhov

Given a differentiable network architecture and loss function, we revisit optimizing the network's neurons in function space using Boosted Backpropagation (Grubb & Bagnell, 2010), in contrast to optimizing in parameter space. From this…

Machine Learning · Computer Science 2025-02-04 Daniel Munoz

Quadrotor control policies can be trained with high performance using the exact gradients of the rewards to directly optimize policy parameters via backpropagation-through-time (BPTT). However, designing a fully differentiable reward…

Robotics · Computer Science 2025-05-22 Fanxing Li , Fangyu Sun , Tianbao Zhang , Danping Zou

The links between optimal control of dynamical systems and neural networks have proved beneficial both from a theoretical and from a practical point of view. Several researchers have exploited these links to investigate the stability of…

Optimization and Control · Mathematics 2019-02-08 Panos Parpas , Corey Muir

The state-of-the art machine learning approach to training deep neural networks, backpropagation, is implausible for real neural networks: neurons need to know their outgoing weights; training alternates between a bottom-up forward pass…

Machine Learning · Computer Science 2020-10-26 Roman Pogodin , Peter E. Latham

In both machine learning and in computational neuroscience, plasticity in functional neural networks is frequently expressed as gradient descent on a cost. Often, this imposes symmetry constraints that are difficult to reconcile with local…

Neurons and Cognition · Quantitative Biology 2026-04-09 Timo Gierlich , Andreas Baumbach , Akos F. Kungl , Kevin Max , Mihai A. Petrovici