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We present a simple physical model that recapitulates several features of biological evolution, while being based only on thermally-driven attachment and detachment of elementary building blocks. Through its dynamics, this model samples a…

Populations and Evolution · Quantitative Biology 2025-07-11 Guy Bunin , Olivier Rivoire

What fascinates us about animal behavior is its richness and complexity, but understanding behavior and its neural basis requires a simpler description. Traditionally, simplification has been imposed by training animals to engage in a…

Neurons and Cognition · Quantitative Biology 2016-07-13 Greg J. Stephens , Leslie C. Osborne , William Bialek

The mechanical properties within living cells play a critical role in the adaptive regulation of their biological functions upon environmental and internal stimuli. While these properties exhibit nonequilibrium dynamics due to the thermal…

Biological Physics · Physics 2024-08-14 Yuika Ueda , Shinji Deguchi

The physical and bio-mechanical principles that govern undulatory movement on wet surfaces have important applications in physiology, physics, and engineering. The nematode {\it C. elegans}, with its highly stereotypical and functionally…

Fluid Dynamics · Physics 2015-06-03 Xiao N. Shen , J. Sznitman , P. Krajacic , T. Lamitina , P. E. Arratia

Realistic description of patient-specific mechanical properties of clotting dynamics presents a major challenge. Available patient-specific data falls short of robustly characterizing myriads of complex dynamic interactions that happen…

Molecular Networks · Quantitative Biology 2017-05-23 Jayavel Arumugam , Arun Srinivasa

A system is glassy when the observation time is much smaller than the equilibration time. A unifying thermodynamic picture of the glassy state is presented. Slow configurational modes are in quasi-equilibrium at an effective temperature. It…

Statistical Mechanics · Physics 2009-10-31 Th. M. Nieuwenhuizen

The dynamics of active particles is of interest at many levels and is the focus of theoretical and experimental research. There have been many attempts to describe the dynamics of particles affected by random active forces in terms of an…

Statistical Mechanics · Physics 2020-01-08 Dan Wexler , Nir S. Gov , Kim Ø. Rasmussen , Golan Bel

The dynamical behavior of a kind of models with hierarchically constrained dynamics is investigated. The models exhibit many properties resembling real structural glasses. In particular, we focus on the study of time-dependent temperature…

Statistical Mechanics · Physics 2009-11-07 A. Prados , J. J. Brey

Generative models of complex systems often require post-hoc parameter adjustments to produce useful outputs. For example, energy-based models for protein design are sampled at an artificially low ''temperature'' to generate novel,…

Quantitative Methods · Quantitative Biology 2025-12-11 Peter W Fields , Vudtiwat Ngampruetikorn , David J Schwab , Stephanie E Palmer

The mechanical properties of thermally excited two-dimensional crystalline membranes can depend dramatically on their geometry and topology. A particularly relevant example is the effect on the crumpling transition of holes in the membrane.…

Soft Condensed Matter · Physics 2019-10-16 D. Yllanes , D. R. Nelson , M. J. Bowick

Recent experiments on active materials, such as dense bacterial suspensions and microtubule-kinesin motor mixtures, show a promising potential for achieving self-sustained flows. However, to develop active microfluidics it is necessary to…

Soft Condensed Matter · Physics 2019-01-23 Santhan Chandragiri , Amin Doostmohammadi , Julia M Yeomans , Sumesh P Thampi

Years ago Edwards proposed a thermodynamic description of dense granular matter, in which the grains (the `atoms' of the system) interact with inelastic forces. The approach is intriguing but is not justified from first principles, and…

Soft Condensed Matter · Physics 2007-05-23 Hernan A. Makse , Jorge Kurchan

We present an example counter to the widely-accepted concept on equilibrium states that "Any thermodynamic equilibrium state of two component systems is determined by specifying 4 thermodynamic variables that include at least 1 extensive…

Soft Condensed Matter · Physics 2018-05-16 Yuki Norizoe , Toshihiro Kawakatsu

A major limitations for many heat engines is that their functioning demands on-line control, and/or an external fitting between environmental parameters (e.g. temperatures of thermal baths) and internal parameters of the engine. We study a…

Statistical Mechanics · Physics 2016-07-20 A. E. Allahverdyan , S. G. Babajanyan , N. H. Martirosyan , A. V. Melkikh

Organisms move through the world by changing their shape, and here we explore the mapping from shape space to movements in the nematode C. elegans as it crawls on a planar agar surface. We characterize the statistics of the trajectories…

Neurons and Cognition · Quantitative Biology 2016-01-05 Greg J Stephens , Bethany Johnson-Kerner , William Bialek , William S Ryu

Effects of collective modes on thermoelectric properties of a charge density system is studied. We derive the temperature dependence of thermoelectric power and thermal conductivity by applying the linear response theory to Fr\"ohlich…

Other Condensed Matter · Physics 2007-05-23 Hiroyuki Yoshimoto , Susumu Kurihara

Many animals in their natural habitat exhibit collective motion and form complex patterns to tackle environmental difficulties. Several physical and biological factors, such as animal motility, population densities, and chemical cues, play…

Biological Physics · Physics 2019-06-25 Esin Demir , Y. Ilker Yaman , Askin Kocabas

Understanding the realization of thermal equilibrium through the thermalization process in a many-body system is a fundamental and complex scientific question, bridging thermodynamics and classical dynamics and connecting to a host of…

Statistical Mechanics · Physics 2026-04-07 Zhenwei Yao

We employ a novel hydrodynamic framework for active matter coupled to an environment to study the local temperature of an active nematic, assuming proximity to thermal equilibrium. We show that, due to the mechanosensitivity of fuel…

Soft Condensed Matter · Physics 2026-04-15 Jay Armas , Akash Jain , Ruben Lier

Feature interaction selection is a fundamental problem in commercial recommender systems. Most approaches equally enumerate all features and interactions by the same pre-defined operation under expert guidance. Their recommendation is…

Artificial Intelligence · Computer Science 2024-05-30 Runlong Yu , Qixiang Shao , Qi Liu , Huan Liu , Enhong Chen
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