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Related papers: FiltPIM: In-Memory Filter for DNA Sequencing

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Nanopore genome sequencing is the key to enabling personalized medicine, global food security, and virus surveillance. The state-of-the-art base-callers adopt deep neural networks (DNNs) to translate electrical signals generated by nanopore…

Hardware Architecture · Computer Science 2020-08-10 Qian Lou , Sarath Janga , Lei Jiang

This paper discusses recent research that aims to enable computation close to data, an approach we broadly call processing-in-memory (PIM). PIM places computation mechanisms in or near where the data is stored (i.e., inside memory chips or…

Hardware Architecture · Computer Science 2025-02-07 Onur Mutlu , Saugata Ghose , Juan Gómez-Luna , Rachata Ausavarungnirun , Mohammad Sadrosadati , Geraldo F. Oliveira

The widespread integration of embedded systems across various industries has facilitated seamless connectivity among devices and bolstered computational capabilities. Despite their extensive applications, embedded systems encounter…

Cryptography and Security · Computer Science 2024-04-16 Sreenitha Kasarapu , Sathwika Bavikadi , Sai Manoj Pudukotai Dinakarrao

To index the increasing volume of data, modern data indexes are typically stored on SSDs and cached in DRAM. However, searching such an index has resulted in significant I/O traffic due to limited access locality and inefficient cache…

Hardware Architecture · Computer Science 2024-08-05 Yun-Chih Chen , Yuan-Hao Chang , Tei-Wei Kuo

Recent research has sought to accelerate cryptographic hash functions as they are at the core of modern cryptography. Traditional designs, however, suffer from the von Neumann bottleneck that originates from the separation of processing and…

Hardware Architecture · Computer Science 2022-06-03 Batel Oved , Orian Leitersdorf , Ronny Ronen , Shahar Kvatinsky

Processing in-memory (PIM) is promising to accelerate neural networks (NNs) because it minimizes data movement and provides large computational parallelism. Similar to machine learning accelerators, application mapping, which determines the…

Hardware Architecture · Computer Science 2024-07-02 Xuan Wang , Minxuan Zhou , Tajana Rosing

Processing-in-DRAM (DRAM-PIM) has emerged as a promising technology for accelerating memory-intensive operations in modern applications, such as Large Language Models (LLMs). Despite its potential, current software stacks for DRAM-PIM face…

Hardware Architecture · Computer Science 2025-06-03 Yongwon Shin , Dookyung Kang , Hyojin Sung

The von Neumann architecture, in which the memory and the computation units are separated, demands massive data traffic between the memory and the CPU. To reduce data movement, new technologies and computer architectures have been explored.…

Emerging Technologies · Computer Science 2022-09-01 Adi Eliahu , Rotem Ben-Hur , Ronny Ronen , Shahar Kvatinsky

Bulk-bitwise processing-in-memory (PIM), where large bitwise operations are performed in parallel by the memory array itself, is an emerging form of computation with the potential to mitigate the memory wall problem. This paper examines the…

Hardware Architecture · Computer Science 2023-09-29 Ben Perach , Ronny Ronen , Benny Kimelfeld , Shahar Kvatinsky

Digital memristive processing-in-memory overcomes the memory wall through a fundamental storage device capable of stateful logic within crossbar arrays. Dynamically dividing the crossbar arrays by adding memristive partitions further…

Hardware Architecture · Computer Science 2022-06-10 Orian Leitersdorf , Ronny Ronen , Shahar Kvatinsky

Processing-in-memory (PIM) architectures have demonstrated great potential in accelerating numerous deep learning tasks. Particularly, resistive random-access memory (RRAM) devices provide a promising hardware substrate to build PIM…

Hardware Architecture · Computer Science 2022-02-01 Weidong Cao , Yilong Zhao , Adith Boloor , Yinhe Han , Xuan Zhang , Li Jiang

Logic-in-memory (LIM) describes the execution of logic gates within memristive crossbar structures, promising to improve performance and energy efficiency. Utilizing only binary values, LIM particularly excels in accelerating binary neural…

We show that the wavefront algorithm can achieve higher pairwise read alignment throughput on a UPMEM PIM system than on a server-grade multi-threaded CPU system.

Hardware Architecture · Computer Science 2022-04-26 Safaa Diab , Amir Nassereldine , Mohammed Alser , Juan Gómez Luna , Onur Mutlu , Izzat El Hajj

Processing-in-memory (PIM) architectures bring computation closer to data, reducing the processor-memory transfer bottleneck in traditional processor-centric designs. Novel hardware solutions, such as UPMEM's in-memory processing…

Emerging Technologies · Computer Science 2026-04-10 Peterson Yuhala , Mpoki Mwaisela , Pascal Felber , Valerio Schiavoni

Spurred by widening gap between data processing speed and data communication speed in Von-Neumann computing architectures, some bioinformatic applications have harnessed the computational power of Processing-in-Memory (PIM) platforms.…

Hardware Architecture · Computer Science 2020-08-17 Shaahin Angizi , Naima Ahmed Fahmi , Wei Zhang , Deliang Fan

The emerging memristive Memory Processing Unit (mMPU) overcomes the memory wall through memristive devices that unite storage and logic for real processing-in-memory (PIM) systems. At the core of the mMPU is stateful logic, which is…

Hardware Architecture · Computer Science 2022-07-01 Orian Leitersdorf , Ronny Ronen , Shahar Kvatinsky

Although deep learning-based personalized recommendation systems provide qualified recommendations, they strain data center resources. The main bottleneck is the embedding layer, which is highly memory-intensive due to its sparse, irregular…

Hardware Architecture · Computer Science 2025-11-26 Youngsuk Kim , Junghwan Lim , Hyuk-Jae Lee , Chae Eun Rhee

Digital processing-in-memory (PIM) architectures are rapidly emerging to overcome the memory-wall bottleneck by integrating logic within memory elements. Such architectures provide vast computational power within the memory itself in the…

Hardware Architecture · Computer Science 2023-04-18 Orian Leitersdorf , Dean Leitersdorf , Jonathan Gal , Mor Dahan , Ronny Ronen , Shahar Kvatinsky

Modern computing systems suffer from the dichotomy between computation on one side, which is performed only in the processor (and accelerators), and data storage/movement on the other, which all other parts of the system are dedicated to.…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-05-14 Onur Mutlu , Saugata Ghose , Juan Gómez-Luna , Rachata Ausavarungnirun

Computing-in-memory (CIM) has attracted significant attentions in recent years due to its massive parallelism and low power consumption. However, current CIM designs suffer from large area overhead of small CIM macros and bad programmablity…

Hardware Architecture · Computer Science 2022-05-04 Shu-Hung Kuo , Tian-Sheuan Chang