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The controversy about statistical significance vs. scientific relevance is more than 100 years old. But still nowadays null hypothesis significance testing is considered as gold standard in many empirical fields from economics and social…

Applications · Statistics 2022-11-23 Uwe Hassler

In traditional hypothesis testing one must pre-specify the significance level $\alpha$ to bound the `size' of the test: its probability to falsely reject the hypothesis. Indeed, a data-dependent selection of $\alpha$ would generally distort…

Statistics Theory · Mathematics 2025-12-03 Nick W. Koning

While Null Hypothesis Significance Testing (NHST) remains a widely used statistical tool, it suffers from several shortcomings in its common usage, such as conflating statistical and practical significance, the formulation of inappropriate…

Statistical analysis is often used to evaluate the evidence for or against scientific hypotheses, and various statistics (e.g., p-values, likelihood ratios, Bayes factors) are interpreted as measures of evidence strength. Here I consider…

Other Statistics · Statistics 2018-05-30 Veronica J. Vieland

Researchers often misinterpret and misrepresent statistical outputs. This abuse has led to a large literature on modification or replacement of testing thresholds and $P$-values with confidence intervals, Bayes factors, and other devices.…

Methodology · Statistics 2020-10-02 Zad Rafi , Sander Greenland

Despite frequent calls for the overhaul of null hypothesis significance testing (NHST), this controversial procedure remains ubiquitous in behavioral, social and biomedical teaching and research. Little change seems possible once the…

Other Statistics · Statistics 2016-03-25 Jose D. Perezgonzalez

Null hypothesis significance testing remains popular despite decades of concern about misuse and misinterpretation. We believe that much of the problem is due to language: significance testing has little to do with other meanings of the…

Other Statistics · Statistics 2018-10-16 Jonathan Dushoff , Morgan P. Kain , Benjamin M. Bolker

Likelihood-based methods of statistical inference provide a useful general methodology that is appealing, as a straightforward asymptotic theory can be applied for their implementation. It is important to assess the relationships between…

Statistics Theory · Mathematics 2015-03-20 Thomas J. DiCiccio , Todd A. Kuffner , G. Alastair Young , Russell Zaretzki

When a scientist performs an experiment they normally acquire a set of measurements and are expected to demonstrate that their results are "statistically significant" thus confirming whatever hypothesis they are testing. The main method for…

Other Statistics · Statistics 2011-09-30 Jacob Levman

This paper develops an interpretive framework for divergence P-values and S-values within a descriptive frequentist perspective. Statistical analysis is framed as operating within idealized worlds defined by a set of assumptions and a…

Other Statistics · Statistics 2026-03-31 Alessandro Rovetta

Hypothesis testing is a central statistical method in psychological research and the cognitive sciences. While the problems of null hypothesis significance testing (NHST) have been debated widely, few attractive alternatives exist. In this…

Methodology · Statistics 2020-06-08 Riko Kelter , Julio Michael Stern

Much of science is (rightly or wrongly) driven by hypothesis testing. Even in situations where the hypothesis testing paradigm is correct, the common practice of basing inferences solely on p-values has been under intense criticism for over…

Methodology · Statistics 2015-12-31 M. J. Bayarri , Daniel J. Benjamin , James O. Berger , Thomas M. Sellke

Null Hypothesis Significance Testing (NHST) has long been central to the scientific project, guiding theory development and supporting evidence-based intervention and decision-making. Recent years, however, have seen growing awareness of…

Methodology · Statistics 2020-10-16 Fintan Costello , Paul Watts

We examine the role of trustworthiness and trust in statistical inference, arguing that it is the extent of trustworthiness in inferential statistical tools which enables trust in the conclusions. Certain tools, such as the p-value and…

Methodology · Statistics 2021-05-11 David J. Hand

Assigning significance in high-dimensional regression is challenging. Most computationally efficient selection algorithms cannot guard against inclusion of noise variables. Asymptotically valid p-values are not available. An exception is a…

Methodology · Statistics 2009-06-12 Nicolai Meinshausen , Lukas Meier , Peter Bühlmann

We present a new test when there is a nuisance parameter under the alternative hypothesis. The test exploits the p-value occupation time [PVOT], the measure of the nuisance parameter subset on which a p-value test based on a a test…

Methodology · Statistics 2023-01-02 Jonathan B. Hill

We introduce the notion of p*-values (p*-variables), which generalizes p-values (p-variables) in several senses. The new notion has four natural interpretations: operational, probabilistic, Bayesian, and frequentist. A main example of a…

Statistics Theory · Mathematics 2022-02-24 Ruodu Wang

The machine learning community adopted the use of null hypothesis significance testing (NHST) in order to ensure the statistical validity of results. Many scientific fields however realized the shortcomings of frequentist reasoning and in…

Machine Learning · Statistics 2017-07-18 Alessio Benavoli , Giorgio Corani , Janez Demsar , Marco Zaffalon

This article gives a survey of the e-value, a statistical significance measure a.k.a. the evidence rendered by observational data, X, in support of a statistical hypothesis, H, or, the other way around, the epistemic value of H given X. The…

Methodology · Statistics 2020-04-29 Julio Michael Stern , Carlos Alberto de Braganca Pereira

In contrast to its common definition and calculation, interpretation of p-values diverges among statisticians. Since p-value is the basis of various methodologies, this divergence has led to a variety of test methodologies and evaluations…

Methodology · Statistics 2012-12-27 Tomokazu Konishi