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Insulin resistance (IR) is a key precursor to diabetes and a significant risk factor for cardiovascular disease. Traditional IR assessment methods require multiple blood tests. We developed a simple AI model using only fasting blood glucose…

Machine Learning · Computer Science 2025-03-10 Weihao Gao , Zhuo Deng , Zheng Gong , Ziyi Jiang , Lan Ma

Background and objective: Diabetes is one of the four leading causes of death worldwide, necessitating daily blood glucose monitoring. While sweat offers a promising non-invasive alternative for glucose monitoring, its application remains…

Quantitative Methods · Quantitative Biology 2024-12-05 Xiaoyu Yin , Elisabetta Peri , Eduard Pelssers , Jaap den Toonder , Lisa Klous , Hein Daanen , Massimo Mischi

Diabetes mellitus is a global health crisis characterized by poor blood sugar regulation, impacting millions of people worldwide and leading to severe complications and mortality. Although Type 1 Diabetes Mellitus (T1DM) has a lower number…

Other Quantitative Biology · Quantitative Biology 2025-04-14 Rinrada Jadsadaphongphaibool , Dadi Bi , Christian D. Lorenz , Yansha Deng , Robert Schober

Continuous glucose monitoring (CGM) provides dense and dynamic glucose profiles that enable reliable estimation of Ambulatory Glucose Profile (AGP) metrics, such as Time in Range (TIR), Time Below Range (TBR), and Time Above Range (TAR).…

Machine Learning · Computer Science 2025-10-09 Canyu Lei , Benjamin Lobo , Jianxin Xie

Functional connectivity analysis is an important tool for characterizing interactions among brain regions, particularly in studies of neurodegenerative disorders such as Alzheimer's disease (AD). Gaussian graphical models (GGMs) provide a…

Methodology · Statistics 2026-04-14 Panpan Zhang , Shiying Xiao , W. Hudson Robb , Dandan Liu , Angela L. Jefferson , Jun Yan

Cardiovascular diseases (CVDs) are notably prevalent among patients with obstructive sleep apnea (OSA), posing unique challenges in predicting CVD progression due to the intricate interactions of comorbidities. Traditional models typically…

Applications · Statistics 2024-07-02 Duy Nguyen , Ca Hoang , Phat K. Huynh , Tien Truong , Dang Nguyen , Abhay Sharma , Trung Q. Le

The conventional method of glucose measurement such as pricking blood from the body is prevalent which brings pain and trauma. Invasive methods of measurement sometimes raise the risk of blood infection to the patient. Sometimes, some of…

Medical Physics · Physics 2023-08-24 Prateek Jain , Amit Joshi , Saraju Mohanty

Postprandial hyperglycemia, marked by the blood glucose level exceeding the normal range after consuming a meal, is a critical indicator of progression toward type 2 diabetes in people with prediabetes and in healthy individuals. A key…

Modeling the dynamics of probability distributions from time-dependent data samples is a fundamental problem in many fields, including digital health. The goal is to analyze how the distribution of a biomarker, such as glucose, changes over…

Machine Learning · Statistics 2025-09-18 Antonio Álvarez-López , Marcos Matabuena

Intensive care unit (ICU) patients exhibit erratic blood glucose (BG) fluctuations, including hypoglycemic and hyperglycemic episodes, and require exogenous insulin delivery to keep their BG in healthy ranges. Glycemic control via glycemic…

This paper presents a novel approach to noninvasive hyperglycemia monitoring utilizing electrocardiograms (ECG) from an extensive database comprising 1119 subjects. Previous research on hyperglycemia or glucose detection using ECG has been…

Signal Processing · Electrical Eng. & Systems 2024-03-13 MohammadReza Hosseinzadehketilateh , Banafsheh Adami , Nima Karimian

Clinical time-series forecasting is increasingly studied for decision support, yet standard aggregate metrics can obscure whether a model is actually useful for the task it is meant to serve. In safety-critical settings, low average error…

Machine Learning · Computer Science 2026-05-04 Alireza Namazi , Heman Shakeri

In the U.S., over a third of adults are pre-diabetic, with 80\% unaware of their status. This underlines the need for better glucose monitoring to prevent type 2 diabetes and related heart diseases. Existing wearable glucose monitors are…

Signal Processing · Electrical Eng. & Systems 2024-06-26 Yidong Zhu , Nadia B Aimandi , Mohammad Arif Ul Alam

Repeated longitudinal measurements are commonly used to model long-term disease progression, and timing and number of assessments per patient may vary, leading to irregularly spaced and sparse data. Longitudinal trajectories may exhibit…

Continuous glucose monitoring (CGM) is central to diabetes care, but explaining CGM patterns clearly and empathetically remains time-intensive. Evidence for retrieval-grounded large language model (LLM) systems in CGM-informed counseling…

Computation and Language · Computer Science 2026-04-17 Zhijun Guo , Alvina Lai , Emmanouil Korakas , Aristeidis Vagenas , Irshad Ahamed , Christo Albor , Hengrui Zhang , Justin Healy , Kezhi Li

A common test for the diagnosis of type 2 diabetes is the Oral Glucose Tolerance Test (OGTT). Recent developments in the study of OGTT tests have framed it as a Bayesian inverse problem. These data analysis advances promise great…

Applications · Statistics 2023-03-14 Nicolás Kuschinski , J. Andrés Christe , Adriana Monroy

The goal of this paper is to propose a new mathematical model for the combined effect of different treatments and lifestyles on the glucose-insulin dynamics of Type 2 diabetes (T2D) patients. The model gives the possibility to take into…

Systems and Control · Electrical Eng. & Systems 2023-01-11 Mohamad Al Ahdab , John Leth , Torben Knudsen , Peter Vestergaard , Henrik Clausen

Fuzzy Cognitive Maps (FCMs) are soft computing technique that follows an approach similar to human reasoning and human decision-making process, making them a valuable modeling and simulation methodology. Medical Decision Systems are complex…

Artificial Intelligence · Computer Science 2021-08-10 Anand M. Shukla , Pooja D. Pandit , Vasudev M. Purandare , Anuradha Srinivasaraghavan

A deep learning network was used to predict future blood glucose levels, as this can permit diabetes patients to take action before imminent hyperglycaemia and hypoglycaemia. A sequential model with one long-short-term memory (LSTM) layer,…

Machine Learning · Computer Science 2018-09-12 Qingnan Sun , Marko V. Jankovic , Lia Bally , Stavroula G. Mougiakakou

The paper investigates the escalating concerns surrounding the surge in diabetes cases, exacerbated by the COVID-19 pandemic, and the subsequent strain on medical resources. The research aims to construct a predictive model quantifying…

Applications · Statistics 2025-02-04 Jorden Lam , Kunpeng Xu
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