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To best of the authors knowledge, this article presents the first-ever non-invasive glucometer that takes into account serum glucose for high accuracy. In case of blood glucose measurement, serum glucose value has always been considered…

Signal Processing · Electrical Eng. & Systems 2021-06-28 Prateek Jain , Amit M Joshi , Navneet Agrawal , Saraju Mohanty

In the context of time-series forecasting, we propose a LSTM-based recurrent neural network architecture and loss function that enhance the stability of the predictions. In particular, the loss function penalizes the model, not only on the…

Signal Processing · Electrical Eng. & Systems 2020-09-09 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

Functional ultrasound imaging (fUSI) is a cutting-edge technology that measures changes in cerebral blood volume (CBV) by detecting backscattered echoes from red blood cells moving within its field of view (FOV). It offers high…

Neurons and Cognition · Quantitative Biology 2025-08-20 Jared Deighton , Shan Zhong , Kofi Agyeman , Wooseong Choi , Charles Liu , Darrin Lee , Vasileios Maroulas , Vasileios Christopoulos

Effective diabetes management relies heavily on the continuous monitoring of blood glucose levels, traditionally achieved through invasive and uncomfortable methods. While various non-invasive techniques have been explored, such as optical,…

Machine Learning · Computer Science 2024-08-16 Nihat Ahmadli , Mehmet Ali Sarsil , Onur Ergen

Accurate prediction of future blood glucose (BG) levels can effectively improve BG management for people living with diabetes, thereby reducing complications and improving quality of life. The state of the art of BG prediction has been…

Machine Learning · Computer Science 2024-02-27 Chengzhe Piao , Taiyu Zhu , Stephanie E Baldeweg , Paul Taylor , Pantelis Georgiou , Jiahao Sun , Jun Wang , Kezhi Li

Precise glucose level monitoring is critical for people with diabetes to avoid serious complications. While there are several methods for continuous glucose level monitoring, research on maintenance devices is limited. To mitigate the gap,…

Machine Learning · Computer Science 2024-06-10 Azmine Toushik Wasi

Wearable devices permit the continuous monitoring of biological processes, such as blood glucose metabolism, and behavior, such as sleep quality and physical activity. The continuous monitoring often occurs in epochs of 60 seconds over…

Methodology · Statistics 2024-04-23 Yuanyuan Luan , Roger S. Zoh , Erjia Cui , Xue Lan , Sneha Jadhav , Carmen D. Tekwe

To avoid serious diabetic complications, people with type 1 diabetes must keep their blood glucose levels (BGLs) as close to normal as possible. Insulin dosages and carbohydrate consumption are important considerations in managing BGLs.…

Machine Learning · Computer Science 2021-05-19 Jeremy Beauchamp , Razvan Bunescu , Cindy Marling , Zhongen Li , Chang Liu

In the world today, diabetic complications are a major factor in the disease's high mortality rate. Diabetes mellitus has been a major source of concern for decades due to its global prevalence and the resulting rising costs to individuals,…

Medical Physics · Physics 2023-10-18 Umme Hafsa Momy

This article compares ten recently proposed neural networks and proposes two ensemble neural network-based models for blood glucose prediction. All of them are tested under the same dataset, preprocessing workflow, and tools using the…

Quantitative Methods · Quantitative Biology 2021-09-07 Felix Tena , Oscar Garnica , Juan Lanchares , J. Ignacio Hidalgo

We develop a new model of insulin-glucose dynamics for forecasting blood glucose in type 1 diabetics. We augment an existing biomedical model by introducing time-varying dynamics driven by a machine learning sequence model. Our model…

Machine Learning · Statistics 2020-08-10 Andrew C. Miller , Nicholas J. Foti , Emily Fox

Non-invasive glucose monitoring remains a critical challenge in the management of diabetes. HRV during sleep shows promise for glucose prediction however, age-related autonomic changes significantly confound traditional HRV analyses. We…

Signal Processing · Electrical Eng. & Systems 2025-08-20 Md Basit Azam , Sarangthem Ibotombi Singh

Research in diabetes, especially when it comes to building data-driven models to forecast future glucose values, is hindered by the sensitive nature of the data. Because researchers do not share the same data between studies, progress is…

Quantitative Methods · Quantitative Biology 2020-09-10 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

Daytime hypoglycemia should be accurately predicted to achieve normoglycemia and to avoid disastrous situations. Hypoglycemia, an abnormally low blood glucose level, is divided into daytime hypoglycemia and nocturnal hypoglycemia. Many…

Machine Learning · Statistics 2017-05-01 Miyeon Jung , You-Bin Lee , Sang-Man Jin , Sung-Min Park

AEGIS study possesses unique information on longitudinal changes in circulating glucose through continuous glucose monitoring technology (CGM). However, as usual in longitudinal medical studies, there is a significant amount of missing data…

Machine Learning · Statistics 2020-12-15 Marcos Matabuena , Paulo Félix , Carlos Meijide-Garcia , Francisco Gude

In this paper, we build a new, simple, and interpretable mathematical model to estimate and forecast physiology related to the human glucose-insulin system, constrained by available data. By constructing a simple yet flexible model class…

Quantitative Methods · Quantitative Biology 2022-09-22 M. Sirlanci , M. E. Levine , C. C. Low Wang , D. J. Albers , A. M. Stuart

In the case of diabetes, fingertip pricking for a blood sample is inconvenient for glucose measurement. Invasive approaches like laboratory test and one-touch glucometer enhance the risk of blood-related infections. To mitigate this…

Signal Processing · Electrical Eng. & Systems 2021-06-28 Prateek Jain , Amit M. Joshi , Saraju P. Mohanty

The dead-in-bed syndrome describes the sudden and unexplained death of young individuals with Type 1 Diabetes (T1D) without prior long-term complications. One leading hypothesis attributes this phenomenon to nocturnal hypoglycemia (NH), a…

Machine Learning · Computer Science 2025-04-15 Marco Voegeli , Sonia Laguna , Heike Leutheuser , Marc Pfister , Marie-Anne Burckhardt , Julia E Vogt

The early detection of Alzheimer's disease (AD) requires an understanding of the relationships between a wide range of features. Conditional independencies and partial correlations are suitable measures for these relationships, because they…

Applications · Statistics 2025-01-22 Lucas Vogels , Reza Mohammadi , Marit Schoonhoven , S. Ilker Birbil , Martin Dyrba

Around a third of type 2 diabetes patients (T2D) are escalated to basal insulin injections. Basal insulin dose is titrated to achieve a tight glycemic target without undue hypoglycemic risk. In the standard of care (SoC), titration is based…

Systems and Control · Electrical Eng. & Systems 2023-09-19 Anas El Fathi , Mohammadreza Ganji , Dimitri Boiroux , Henrik Bengtsson , Marc D. Breton