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Functional Magnetic Resonance Imaging (fMRI) is an imaging technique widely used to study human brain activity. fMRI signals in areas across the brain transiently synchronise and desynchronise their activity in a highly structured manner,…

Machine Learning · Computer Science 2025-08-12 Yiran Huang , Amirhossein Nouranizadeh , Christine Ahrends , Mengjia Xu

Medical multimodal representation learning aims to integrate heterogeneous data into unified patient representations to support clinical outcome prediction. However, real-world medical datasets commonly contain systematic biases from…

Machine Learning · Computer Science 2026-05-19 Xiaoguang Zhu , Linxiao Gong , Lianlong Sun , Yang Liu , Haoyu Wang , Jing Liu

The relationship between brain structure and function is critical for revealing the pathogenesis of brain disorders, including Alzheimer's disease (AD). However, mapping brain structure to function connections is a very challenging task. In…

Artificial Intelligence · Computer Science 2025-02-25 Tong Zhou , Chen Ding , Changhong Jing , Feng Liu , Kevin Hung , Hieu Pham , Mufti Mahmud , Zhihan Lyu , Sibo Qiao , Shuqiang Wang , Kim-Fung Tsang

Traditional model-based diagnosis relies on constructing explicit system models, a process that can be laborious and expertise-demanding. In this paper, we propose a novel framework that combines concepts of model-based diagnosis with deep…

Artificial Intelligence · Computer Science 2023-10-11 Jan Lukas Augustin , Oliver Niggemann

Recent advances in deep learning have had a methodological and practical impact on brain-computer interface research. Among the various deep network architectures, convolutional neural networks have been well suited for…

Signal Processing · Electrical Eng. & Systems 2020-03-06 Wonjun Ko , Eunjin Jeon , Seungwoo Jeong , Heung-Il Suk

Intracranial arteries are critical blood vessels that supply the brain with oxygenated blood. Intracranial artery labels provide valuable guidance and navigation to numerous clinical applications and disease diagnoses. Various machine…

Image and Video Processing · Electrical Eng. & Systems 2022-11-02 Yaxin Zhu , Peisheng Qian , Ziyuan Zhao , Zeng Zeng

Purpose: Different Magnetic resonance imaging (MRI) modalities of the same anatomical structure are required to present different pathological information from the physical level for diagnostic needs. However, it is often difficult to…

Image and Video Processing · Electrical Eng. & Systems 2021-09-15 Yuchen Fei , Bo Zhan , Mei Hong , Xi Wu , Jiliu Zhou , Yan Wang

Functional Magnetic Resonance Image (fMRI) is commonly employed to study human brain activity, since it offers insight into the relationship between functional fluctuations and human behavior. To enhance analysis and comprehension of brain…

Artificial Intelligence · Computer Science 2025-02-04 Song Wang , Zhenyu Lei , Zhen Tan , Jiaqi Ding , Xinyu Zhao , Yushun Dong , Guorong Wu , Tianlong Chen , Chen Chen , Aiying Zhang , Jundong Li

Complex functional brain network analyses have exploded over the last eight years, gaining traction due to their profound clinical implications. The application of network science (an interdisciplinary offshoot of graph theory) has…

Methodology · Statistics 2013-10-28 Sean L. Simpson , F. DuBois Bowman , Paul J. Laurienti

The black-box nature of deep learning models prevents them from being completely trusted in domains like biomedicine. Most explainability techniques do not capture the concept-based reasoning that human beings follow. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2022-03-15 Avinash Kori , Parth Natekar , Ganapathy Krishnamurthi , Balaji Srinivasan

Deep learning methods for graphs achieve remarkable performance on many node-level and graph-level prediction tasks. However, despite the proliferation of the methods and their success, prevailing Graph Neural Networks (GNNs) neglect…

Machine Learning · Computer Science 2020-11-10 Emily Alsentzer , Samuel G. Finlayson , Michelle M. Li , Marinka Zitnik

Complex functional brain networks are large networks of brain regions and functional brain connections. Statistical characterizations of these networks aim to quantify global and local properties of brain activity with a small number of…

Neurons and Cognition · Quantitative Biology 2011-07-19 Mikail Rubinov , Olaf Sporns

Deep neural networks have been developed drawing inspiration from the brain visual pathway, implementing an end-to-end approach: from image data to video object classes. However building an fMRI decoder with the typical structure of…

Machine Learning · Statistics 2017-01-10 Michele Svanera , Sergio Benini , Gal Raz , Talma Hendler , Rainer Goebel , Giancarlo Valente

Human brain anatomy and function display a combination of modular and hierarchical organization, suggesting the importance of both cohesive structures and variable resolutions in the facilitation of healthy cognitive processes. However,…

Neurons and Cognition · Quantitative Biology 2015-06-18 Christian Lohse , Danielle S. Bassett , Kelvin O. Lim , Jean M. Carlson

Functional magnetic resonance imaging (fMRI) has been commonly used to construct functional connectivity networks (FCNs) of the human brain. TFCNs are primarily limited to quantifying pairwise relationships between ROIs ignoring higher…

Signal Processing · Electrical Eng. & Systems 2025-07-15 Duc Vu , Selin Aviyente

The white-matter (micro-)structural architecture of the brain promotes synchrony among neuronal populations, giving rise to richly patterned functional connections. A fundamental problem for systems neuroscience is determining the best way…

Neurons and Cognition · Quantitative Biology 2022-11-15 Yueting Li , Qingyue Wei , Ehsan Adeli , Kilian M. Pohl , Qingyu Zhao

This paper proposes a novel approach of integrating different neuroimaging techniques to characterize an autistic brain. Different techniques like EEG, fMRI and DTI have traditionally been used to find biomarkers for autism, but there have…

The integration and transmission of information in the brain are dependent on the interplay between structural and dynamical properties. Implicit in any pursuit aimed at understanding neural dynamics from appropriate sets of mathematically…

Neurons and Cognition · Quantitative Biology 2020-06-30 Joshua M. Roldan , Sebastian Pardo G. , Vivek Kurien George , Gabriel A. Silva

Reconstructing seeing images from fMRI recordings is an absorbing research area in neuroscience and provides a potential brain-reading technology. The challenge lies in that visual encoding in brain is highly complex and not fully revealed.…

Neural and Evolutionary Computing · Computer Science 2021-01-29 Tao Fang , Yu Qi , Gang Pan

Spontaneous brain activity, as observed in functional neuroimaging, has been shown to display reproducible structure that expresses brain architecture and carries markers of brain pathologies. An important view of modern neuroscience is…

Machine Learning · Statistics 2010-11-15 Gaël Varoquaux , Alexandre Gramfort , Jean Baptiste Poline , Bertrand Thirion