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Trajectory inference seeks to recover the temporal dynamics of a population from snapshots of its (uncoupled) temporal marginals, i.e. where observed particles are not tracked over time. Prior works addressed this challenging problem under…

Machine Learning · Computer Science 2025-02-27 Anming Gu , Edward Chien , Kristjan Greenewald

Trajectory Inference (TI) seeks to recover latent dynamical processes from snapshot data, where only independent samples from time-indexed marginals are observed. In applications such as single-cell genomics, destructive measurements make…

Machine Learning · Computer Science 2026-04-23 Chao Wang , Luca Nepote , Giulio Franzese , Pietro Michiardi

Trajectory inference investigates how to interpolate paths between observed timepoints of dynamical systems, such as temporally resolved population distributions, with the goal of inferring trajectories at unseen times and better…

Machine Learning · Computer Science 2026-03-18 Aaron Zweig , Mingxuan Zhang , David A. Knowles , Elham Azizi

Capturing data from dynamic processes through cross-sectional measurements is seen in many fields, such as computational biology. Trajectory inference deals with the challenge of reconstructing continuous processes from such observations.…

Machine Learning · Computer Science 2025-03-12 Amartya Banerjee , Harlin Lee , Nir Sharon , Caroline Moosmüller

We devise a theoretical framework and a numerical method to infer trajectories of a stochastic process from samples of its temporal marginals. This problem arises in the analysis of single cell RNA-sequencing data, which provide high…

Machine Learning · Statistics 2023-04-04 Hugo Lavenant , Stephen Zhang , Young-Heon Kim , Geoffrey Schiebinger

The numerical simulation of realistic reactive flows is a major challenge due to the stiffness and high dimension of the corresponding kinetic differential equations. Manifold-based model reduction techniques address this problem by…

Dynamical Systems · Mathematics 2026-01-06 Jörn Dietrich , Dirk Lebiedz

We present a novel methodology based on filtered data and moving averages for estimating effective dynamics from observations of multiscale systems. We show in a semi-parametric framework of the Langevin type that our approach is…

Numerical Analysis · Mathematics 2022-01-25 Giacomo Garegnani , Andrea Zanoni

As written by statistician George Box "All models are wrong, but some are useful", standard diffusion derivation or Feynman path ensembles use nonphysical infinite velocity/kinetic energy nowhere differentiable trajectories - what seems…

Statistical Mechanics · Physics 2024-04-23 Jarek Duda

Variational inference, such as the mean-field (MF) approximation, requires certain conjugacy structures for efficient computation. These can impose unnecessary restrictions on the viable prior distribution family and further constraints on…

Statistics Theory · Mathematics 2023-09-11 Rentian Yao , Yun Yang

Network inference, the task of reconstructing interactions in a complex system from experimental observables, is a central yet extremely challenging problem in systems biology. While much progress has been made in the last two decades,…

Quantitative Methods · Quantitative Biology 2024-09-12 Stephen Y Zhang

Diffusion models show promising generation capability for a variety of data. Despite their high generation quality, the inference for diffusion models is still time-consuming due to the numerous sampling iterations required. To accelerate…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Kexun Zhang , Xianjun Yang , William Yang Wang , Lei Li

In this paper, we aim to forecast a future trajectory distribution of a moving agent in the real world, given the social scene images and historical trajectories. Yet, it is a challenging task because the ground-truth distribution is…

Computer Vision and Pattern Recognition · Computer Science 2022-04-01 Ke Guo , Wenxi Liu , Jia Pan

The problem of determining dynamical models and trajectories that describe observed time-series data allowing for the understanding, prediction and possibly control of complex systems in nature is of a great interest in a wide variety of…

Data Analysis, Statistics and Probability · Physics 2007-05-23 V. N. Smelyanskiy , D. G. Luchinsky , M. Millons

We present a new method to sample conditioned trajectories of a system evolving under Langevin dynamics, based on Brownian bridges. The trajectories are conditioned to end at a certain point (or in a certain region) in space. The bridge…

Mathematical Physics · Physics 2022-08-17 Patrice Koehl , Henri Orland

The explosion in the availability of GPS-enabled devices has resulted in an abundance of trajectory data. In reality, however, majority of these trajectories are collected at a low sampling rate and only provide partial observations on…

Databases · Computer Science 2016-03-25 Prithu Banerjee , Sayan Ranu , Sriram Raghavan

We focus on the problem estimating a monotone trend function under additive and dependent noise. New point-wise confidence interval estimators under both short- and long-range dependent errors are introduced and studied. These intervals are…

Statistics Theory · Mathematics 2016-02-23 Pramita Bagchi , Moulinath Banerjee , Stilian Stoev

Substantial progress has recently been made in the understanding of the cutoff phenomenon for Markov processes, using an information-theoretic statistics known as varentropy [Sal23; Sal24; Sal25a; PS25]. In the present paper, we propose an…

Probability · Mathematics 2025-09-18 Francesco Pedrotti , Justin Salez

Diffusion and flow-based generative models have achieved remarkable success in domains such as image synthesis, video generation, and natural language modeling. In this work, we extend these advances to weight space learning by leveraging…

Machine Learning · Computer Science 2025-10-17 Daniel Saragih , Deyu Cao , Tejas Balaji

We present a unified framework for solving trajectory optimization problems in a derivative-free manner through the use of sequential convex programming. Traditionally, nonconvex optimization problems are solved by forming and solving a…

Optimization and Control · Mathematics 2025-10-01 Kevin Tracy , John Z. Zhang , Jon Arrizabalaga , Stefan Schaal , Yuval Tassa , Tom Erez , Zachary Manchester

Trajectory prediction is a crucial undertaking in understanding entity movement or human behavior from observed sequences. However, current methods often assume that the observed sequences are complete while ignoring the potential for…

Computer Vision and Pattern Recognition · Computer Science 2023-03-29 Yi Xu , Armin Bazarjani , Hyung-gun Chi , Chiho Choi , Yun Fu
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