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Multiscale modelling presents a multifaceted perspective into understanding the mechanisms of the brain and how neurodegenerative disorders like Parkinson's disease (PD) manifest and evolve over time. In this study, we propose a novel…

Neurons and Cognition · Quantitative Biology 2025-09-18 Aaron Herrera , Hina Shaheen

The proportion of elderly people is increasing worldwide, particularly those living alone in Japan. As elderly people get older, their risks of physical disabilities and health issues increase. To automatically discover these issues at a…

Machine Learning · Computer Science 2024-11-21 Kai Tanaka , Mineichi Kudo , Keigo Kimura , Atsuyoshi Nakamura

Parkinson's disease (PD) is a highly heterogeneous disease, including which motor symptoms are dominating. Imaging biomarkers that support subtype stratification could also improve biological understanding and study design, and enable…

Longitudinal voice biomarkers provide a non-invasive source of information for monitoring Parkinson's disease progression, but their statistical analysis is difficult because repeated measurements from the same subject are correlated,…

Machine Learning · Statistics 2026-04-28 Ran Tong , Lanruo Wang , Tong Wang , Wei Yan

As one of the most prevalent neurodegenerative disorders, Parkinson's disease (PD) has a significant impact on the fine motor skills of patients. The complex interplay of different articulators during speech production and realization of…

Recent studies have demonstrated that analysis of laboratory-quality voice recordings can be used to accurately differentiate people diagnosed with Parkinson's disease (PD) from healthy controls (HC). These findings could help facilitate…

Applications · Statistics 2019-05-22 Siddharth Arora , Ladan Baghai-Ravary , Athanasios Tsanas

Multiple sclerosis is a disease that affects the brain and spinal cord, it can lead to severe disability and has no known cure. The majority of prior work in machine learning for multiple sclerosis has been centered around using Magnetic…

Machine Learning · Computer Science 2023-09-12 Alexander Norcliffe , Lev Proleev , Diana Mincu , Fletcher Lee Hartsell , Katherine Heller , Subhrajit Roy

Human movements in the workspace usually have non-negligible relations with air quality parameters (e.g., CO$_2$, PM2.5, and PM10). We establish a system to monitor indoor human mobility with air quality and assess the interrelationship…

Human-Computer Interaction · Computer Science 2023-06-22 Kyle K. Qin , Mohammad S. Rahaman , Yongli Ren , Chi-Tsun Cheng , Ivan Cole , Flora D. Salim

Parkinson's disease (PD) is a progressive disorder in which symptom burden and functional impairment evolve over time, making severity staging essential for clinical monitoring and treatment planning. However, many computational studies…

Machine Learning · Computer Science 2026-04-21 Md Mezbahul Islam , John Michael Templeton , Christian Poellabauer , Ananda Mohan Mondal

Parkinson's Disease (PD) medication management presents unique challenges due to heterogeneous disease progression and treatment response. Neurologists must balance symptom control with optimal dopaminergic dosing based on functional…

Machine Learning · Computer Science 2025-08-15 Ricardo Diaz-Rincon , Muxuan Liang , Adolfo Ramirez-Zamora , Benjamin Shickel

Agitation is one of the neuropsychiatric symptoms with high prevalence in dementia which can negatively impact the Activities of Daily Living (ADL) and the independence of individuals. Detecting agitation episodes can assist in providing…

Freezing of Gait (FoG) is a common gait deficit among patients diagnosed with Parkinson's Disease (PD). In order to help these patients recover from FoG episodes, Rhythmic Auditory Stimulation (RAS) is needed. The authors propose a…

Signal Processing · Electrical Eng. & Systems 2020-04-14 Gokul H. , Prithvi Suresh , Hari Vignesh B , Pravin Kumaar R , Vineeth Vijayaraghavan

Digital technologies (e.g., mobile phones) can be used to obtain objective, frequent, and real-world digital phenotypes from individuals. However, modeling these data poses substantial challenges since observational data are subject to…

Applications · Statistics 2026-05-12 Tianchen Xu , Yuan Chen , Donglin Zeng , Yuanjia Wang

In the analysis of remote healthcare monitoring data, time series representation learning offers substantial value in uncovering deeper patterns of patient behavior, especially given the fine temporal granularity of the data. In this study,…

Artificial Intelligence · Computer Science 2025-02-17 Jin Cui , Alexander Capstick , Payam Barnaghi , Gregory Scott

Parkinson's Disease (PD) is one of the most prevalent neurodegenerative diseases that affects tens of millions of Americans. PD is highly progressive and heterogeneous. Quite a few studies have been conducted in recent years on predictive…

Computer Vision and Pattern Recognition · Computer Science 2019-05-08 Xi Sheryl Zhang , Lifang He , Kun Chen , Yuan Luo , Jiayu Zhou , Fei Wang

Parkinson's Disease (PD) significantly impacts driving abilities, often leading to early driving cessation or accidents due to reduced motor control and increasing reaction times. To diminish the impact of these symptoms, we developed PANDA…

Human-Computer Interaction · Computer Science 2025-03-11 Tianyang Wen , Xucheng Zhang , Zhirong Wan , Jing Zhao , Yicheng Zhu , Ning Su , Xiaolan Peng , Jin Huang , Wei Sun , Feng Tian , Franklin Mingzhe Li

This paper presents an experimental evaluation on the accuracy of indoor localisation. The research was carried out as part of a European Union project targeting the creation of ICT solutions for older adult care. Current expectation is…

Computers and Society · Computer Science 2020-09-08 Iuliana Marin , Maria Iuliana Bocicor , Arthur-Jozsef Molnar

We present a generalized velocity model to improve localization when using an Inertial Navigation System (INS). This algorithm was applied to correct the velocity of a smart phone based indoor INS system to increase the accuracy by…

Other Computer Science · Computer Science 2016-01-13 Rasika Lakmal Hettiarachchige Don , Jagath Samarabandu

We showcase the practicability of an indoor positioning system (IPS) solely based on Neural Networks (NNs) and the channel state information (CSI) of a (Massive) multiple-input multiple-output (MIMO) communication system, i.e., only build…

Signal Processing · Electrical Eng. & Systems 2019-05-29 Mark Widmaier , Maximilian Arnold , Sebastian Dörner , Sebastian Cammerer , Stephan ten Brink

This work makes multiple scientific contributions to the field of Indoor Localization for Ambient Assisted Living in Smart Homes. First, it presents a Big-Data driven methodology that studies the multimodal components of user interactions…

Human-Computer Interaction · Computer Science 2021-06-30 Nirmalya Thakur , Chia Y. Han
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