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Heterogeneous systems of active matter exhibit a range of complex emergent dynamical patterns. In particular, it is difficult to predict the properties of the mixed system based on its constituents. These considerations are particularly…

Soft Condensed Matter · Physics 2021-04-07 Shlomit Peled , Shawn D. Ryan , Sebastian Heidenreich , Markus Bar , Gil Ariel , Avraham Be'er

Bacterial colonies composed of elongated cells form active nematic fluids that spontaneously self-organise into ordered domains of aligned cells and exhibit self-generated chaotic flows powered by cell growth. While their dynamics have…

Cells are fundamental building blocks of living organisms displaying an array of shapes, morphologies, and textures that encode specific functions and physical behaviors. Elucidating the rules of this code remains a challenge. In this work,…

Bacteria regulate their motility through a variety of mechanisms, including quorum sensing (QS) and other density-dependent responses mediated by diffusible signals. While nonlinear density-dependent motility is well known in active-matter…

Populations and Evolution · Quantitative Biology 2026-01-21 Mattia Mattei , David Soriano-Paños , Alex Arenas

Monolayers of growing non-motile rod-shaped bacteria act as active nematic materials composed of hard particles rather than the flexible components of other commonly studied active nematics. The organization of these granular monolayers has…

Soft Condensed Matter · Physics 2023-05-12 Blake Langeslay , Gabriel Juarez

The self-organization of microbial ecosystems involves a large variety of mechanisms, ranging from biochemical signaling to population dynamics. Among these, the role of motility regulation has been little studied, despite the importance of…

Statistical Mechanics · Physics 2025-03-18 Alberto Dinelli , Ada Altieri , Julien Tailleur

This work examines self-mixing in active nematics, a class of fluids in which mobile topological defects drive chaotic flows in a system comprised of biological filaments and molecular motors. We present experiments that demonstrate how…

We develop an approximate, analytical model for the velocity of defects in active nematics by combining recent results for the velocity of topological defects in nematic liquid crystals with the flow field generated from individual defects…

Soft Condensed Matter · Physics 2024-11-27 Cody D. Schimming , C. J. O. Reichhardt , C. Reichhardt

Using agent-based simulations of self-propelled particles subject to short-range repulsion and nematic alignment we explore the dynamical phases of a dense active material confined to the surface of a sphere. We map the dynamical phase…

Soft Condensed Matter · Physics 2018-04-25 Silke Henkes , M. Cristina Marchetti , Rastko Sknepnek

Active nematics in two dimensions stir themselves efficiently through internally generated chaotic flows, largely driven by motile $+1/2$ disclinations. We investigate how this tendency toward chaotic fluid stirring can, counterintuitively,…

Motivated by recent experiments on growing fibroblasts, we examine the development of nematic order in a colony of elongated cells proliferating on a nematic elastomer substrate. After sparse seeding, the cells divide and grow into locally…

Soft Condensed Matter · Physics 2026-01-06 Toshi Parmar , Fridtjof Brauns , Yimin Luo , M. Cristina Marchetti

Despite the importance that fluid flow plays in transporting and organizing populations, few laboratory systems exist to systematically investigate the impact of advection on their spatial evolutionary dynamics. To address this problem, we…

Soft Condensed Matter · Physics 2019-07-03 Severine Atis , Bryan T. Weinstein , Andrew W. Murray , David R. Nelson

Active fluids, such as cytoskeletal filaments, bacterial colonies and epithelial cell layers, exhibit distinctive orientational coherence, often characterized by nematic order and topological defects. By contrast, little is known about…

Soft Condensed Matter · Physics 2021-04-07 Mattia Serra , Linnea Lemma , Luca Giomi , Zvonimir Dogic , L. Mahadevan

Motility is a fundamental survival strategy of bacteria to navigate porous environments. Swimming cells thrive in quiescent wetlands and sediments at the bottom of the marine water column, where they mediate many essential biogeochemical…

Soft Condensed Matter · Physics 2022-01-11 Amin Dehkharghani , Nicolas Waisbord , Jeffrey S. Guasto

Spatiotemporal patterns in multicellular systems are important to understanding tissue dynamics, for instance, during embryonic development and disease. Here, we use a multiphase field model to study numerically the behavior of a…

Soft Condensed Matter · Physics 2025-02-13 Michael Chiang , Austin Hopkins , Benjamin Loewe , M. Cristina Marchetti , Davide Marenduzzo

Bacterial chemotaxis systems are as diverse as the environments that bacteria inhabit, but how much environmental variation can cells tolerate with a single system? Diversification of a single chemotaxis system could serve as an…

Populations and Evolution · Quantitative Biology 2015-11-30 Nicholas W Frankel , William Pontius , Yann S Dufour , Junjiajia Long , Luis Hernandez- Nunez , Thierry Emonet

Cell alignment often forms nematic order, which can lead to anomalous collective cell flow due to the so-called active force. Although it is appreciated that cell migration is driven by traction force, a quantitative evaluation of the…

Soft Condensed Matter · Physics 2024-02-27 Masahito Uwamichi , He Li , Zihui Zhao , Yisong Yao , Hideo Higuchi , Kyogo Kawaguchi , Masaki Sano

We consider the hydrodynamic theory of an active fluid of self-propelled particles with nematic aligning interactions. This class of materials has polar symmetry at the microscopic level, but forms macrostates of nematic symmetry. We…

Soft Condensed Matter · Physics 2012-04-17 Aparna Baskaran , M. Cristina Marchetti

The role of boundary layers in conventional liquid crystals is commonly subsumed in their anchoring on confining walls. In the classical view, anchoring enslaves the orientational field of the passive material under equilibrium conditions.…

Using novel micro-printing techniques, we develop a versatile experimental setup that allows us to study how lateral confinement tames the active flows and defect properties of the microtubule/kinesin active nematic system. We demonstrate…