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The spreading of bacterial populations is central to processes in agriculture, the environment, and medicine. However, existing models of spreading typically focus on cells in unconfined settings--despite the fact that many bacteria inhabit…

Populations and Evolution · Quantitative Biology 2022-06-07 Daniel B. Amchin , Jenna A. Ott , Tapomoy Bhattacharjee , Sujit S. Datta

Polymers are a primary building block in many biomaterials, often interacting with anisotropic backgrounds. While previous studies have considered polymer dynamics within nematic solvents, rarely are the the effects of anisotropic viscosity…

The topological properties of many materials are central to their behavior, with the dynamics of topological defects being particularly important to intrinsically out-of-equilibrium, active materials. In this paper, local manipulation of…

Soft Condensed Matter · Physics 2019-11-01 David P. Rivas , Tyler N. Shendruk , Robert R. Henry , Daniel H. Reich , Robert L. Leheny

Bacterial swarming is a rapid mass-migration, in which thousands of cells spread collectively to colonize a surface. Physically, swarming is a natural example of active particles that use energy to generate motion. Accordingly,…

Soft Condensed Matter · Physics 2019-11-14 Avraham Be`er , Bella Ilkanaiv , Renan Gross , Daniel B. Kearns , Sebastian Heidenreich , Markus Bär , Gil Ariel

We study the transport of bacteria in a porous media modeled by a square channel containing one cylindrical obstacle via molecular dynamics simulations coupled to a lattice Boltzmann fluid. Our bacteria model is a rod-shaped rigid body…

Soft Condensed Matter · Physics 2020-11-30 Miru Lee , Christoph Lohrmann , Kai Szuttor , Harold Auradou , Christian Holm

Contact inhibition limits migration and proliferation of cells in cell colonies. We consider a multiphase field model to investigate the growth dynamics of a cell colony, composed of proliferating cells. The model takes into account the…

Soft Condensed Matter · Physics 2022-03-14 Harish P. Jain , Dennis Wenzel , Axel Voigt

Densely packed, motile bacteria can adopt collective states not seen in conventional, passive materials. These states remain in many ways mysterious, and their physical characterization can aid our understanding of natural bacterial…

Statistical Mechanics · Physics 2024-06-18 Hisay Lama , Masahiro J. Yamamoto , Yujiro Furuta , Takuro Shimaya , Kazumasa A. Takeuchi

Microbes providing public goods are widespread in nature despite running the risk of being exploited by free-riders. However, the precise ecological factors supporting cooperation are still puzzling. Following recent experiments, we…

Populations and Evolution · Quantitative Biology 2012-03-28 Jonas Cremer , Anna Melbinger , Erwin Frey

Being intrinsically nonequilibrium, active materials can potentially perform functions that would be thermodynamically forbidden in passive materials. However, active systems have diverse local attractors that correspond to distinct…

Soft Condensed Matter · Physics 2024-10-16 Saptorshi Ghosh , Aparna Baskaran , Michael F. Hagan

Microfluidics involves the manipulation of flows at the microscale, typically requiring external power sources to generate pressure gradients. Alternatively, harnessing flows from active fluids, which are usually chaotic, has been proposed…

Cell monolayers are a central model system to tissue biophysics. In vivo, epithelial tissues are curved on the scale of microns, and curvature's role in the onset of spontaneous tissue flows is still not well-understood. Here, we present a…

Biological Physics · Physics 2022-09-21 Samuel Bell , Shao-Zhen Lin , Jean-François Rupprecht , Jacques Prost

Bacterial processes ranging from gene expression to motility and biofilm formation are constantly challenged by internal and external noise. While the importance of stochastic fluctuations has been appreciated for chemotaxis, it is…

Biological Physics · Physics 2011-07-13 Knut Drescher , Jörn Dunkel , Luis H. Cisneros , Sujoy Ganguly , Raymond E. Goldstein

We consider a microscopic field theoretical approach for interacting active nematic particles. With only steric interactions the self-propulsion strength in such systems can lead to different collective behaviour, e.g., synchronized…

Soft Condensed Matter · Physics 2021-02-04 Veit Krause , Axel Voigt

Many bacteria live in natural and clinical environments with abundant macromolecular polymers. Macromolecular fluids commonly display viscoelasticity and non-Newtonian rheological behavior; it is unclear how these complex-fluid properties…

Soft Condensed Matter · Physics 2024-08-27 Ding Cao , Ran Tao , Albane Théry , Song Liu , Arnold J. T. M. Mathijssen , Yilin Wu

The dispersal of cells from an initially constrained location is a crucial aspect of many physiological phenomena ranging from morphogenesis to tumour spreading. In such processes, the way cell-cell interactions impact the motion of single…

In invasive breast cancer, cell clusters of varying sizes and shapes are embedded in the fibrous extracellular matrix (ECM). Although the prevailing view attributes this structure to increasing disorder resulting from loss of function and…

Active turbulence in dense active systems is characterized by high vorticity on a length scale that is large compared to that of individual entities. We describe the properties of active turbulence as momentum propagation is screened by…

Soft Condensed Matter · Physics 2014-12-24 Sumesh P. Thampi , Ramin Golestanian , Julia M. Yeomans

Cell crawling crucially depends on the collective dynamics of the acto-myosin cytoskeleton. However, it remains an open question to what extent cell polarization and persistent motion depend on continuous regulatory mechanisms and…

Biological Physics · Physics 2023-08-11 Fenna Stegemerten , Karin John , Uwe Thiele

Nematic colloids exhibit a large diversity of topological defects and structures induced by colloidal particles in the orientationally ordered liquid crystal host fluids. These defects and field configurations define elastic interactions…

Soft Condensed Matter · Physics 2016-12-30 Bohdan Senyuk , Qingkun Liu , Ye Yuan , Ivan I. Smalyukh

The natural habitats of microorganisms in the human microbiome and ocean and soil ecosystems are full of colloids and macromolecules, which impart non-Newtonian flow properties drastically affecting the locomotion of swimming…

Soft Condensed Matter · Physics 2022-04-01 Shashank Kamdar , Seunghwan Shin , Lorraine F. Francis , Xinliang Xu , Xiang Cheng
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