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The past few years have seen an increasing number of initiatives aimed at integrating information generated outside of confirmatory randomised clinical trials (RCTs) into drug development. However, data generated non-concurrently and…

Methodology · Statistics 2022-11-04 Cornelia Dunger-Baldauf , Rob Hemmings , Frank Bretz , Byron Jones , Anja Schiel , Chris Holmes

Recent multi-object tracking (MOT) systems have leveraged highly accurate object detectors; however, training such detectors requires large amounts of labeled data. Although such data is widely available for humans and vehicles, it is…

Computer Vision and Pattern Recognition · Computer Science 2022-11-09 Travis Mandel , Mark Jimenez , Emily Risley , Taishi Nammoto , Rebekka Williams , Max Panoff , Meynard Ballesteros , Bobbie Suarez

The extensive world knowledge and powerful reasoning capabilities of large language models (LLMs) have attracted significant attention in recommendation systems (RS). Specifically, The chain of thought (CoT) has been shown to improve the…

Information Retrieval · Computer Science 2025-08-22 Yu Xia , Rui Zhong , Zeyu Song , Wei Yang , Junchen Wan , Qingpeng Cai , Chi Lu , Peng Jiang

The ability to generalize experimental results from randomized control trials (RCTs) across locations is crucial for informing policy decisions in targeted regions. Such generalization is often hindered by the lack of identifiability due to…

Econometrics · Economics 2021-12-10 Xinkun Nie , Guido Imbens , Stefan Wager

Benefiting from its ability to efficiently learn how an object is changing, correlation filters have recently demonstrated excellent performance for rapidly tracking objects. Designing effective features and handling model drifts are two…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Xizhe Xue , Ying Li , Qiang Shen

This paper proposes a rapidly-exploring random trees (RRT) algorithm to solve the motion planning problem for hybrid systems. At each iteration, the proposed algorithm, called HyRRT, randomly picks a state sample and extends the search tree…

Robotics · Computer Science 2022-10-28 Nan Wang , Ricardo G. Sanfelice

In the presence of heterogeneity between the randomized controlled trial (RCT) participants and the target population, evaluating the treatment effect solely based on the RCT often leads to biased quantification of the real-world treatment…

Methodology · Statistics 2022-10-05 Dasom Lee , Shu Yang , Xiaofei Wang

When treating depression, clinicians are interested in determining the optimal treatment for a given patient, which is challenging given the amount of treatments available. To advance individualized treatment allocation, integrating data…

This study explores integrating reinforcement learning (RL) with idealised climate models to address key parameterisation challenges in climate science. Current climate models rely on complex mathematical parameterisations to represent…

Machine Learning · Computer Science 2025-04-17 Pritthijit Nath , Henry Moss , Emily Shuckburgh , Mark Webb

Linear mixed models are commonly used in analyzing stepped-wedge cluster randomized trials (SW-CRTs). A key consideration for analyzing a SW-CRT is accounting for the potentially complex correlation structure, which can be achieved by…

Methodology · Statistics 2024-08-21 Yongdong Ouyang , Monica Taljaard , Andrew B Forbes , Fan Li

Although increasingly used for research, electronic health records (EHR) often lack gold-standard assessment of key data elements. Linking EHRs to other data sources with higher-quality measurements can improve statistical inference, but…

Methodology · Statistics 2025-03-05 Jenny Shen , Dane Isenberg , Kristin A. Linn , Rebecca A. Hubbard

Reciprocal recommender systems (RRSs) are crucial in online two-sided matching platforms, such as online job or dating markets, as they need to consider the preferences of both sides of the match. The concentration of recommendations to a…

Information Retrieval · Computer Science 2024-12-02 Kento Nakada , Kazuki Kawamura , Ryosuke Furukawa

Randomized controlled trials are the gold standard for causal inference and play a pivotal role in modern evidence-based medicine. However, the sample sizes they use are often too limited to draw significant causal conclusions for subgroups…

Methodology · Statistics 2024-04-26 Xi Lin , Jens Magelund Tarp , Robin J. Evans

We consider estimating the conditional average treatment effect for everyone by eliminating confounding and selection bias. Unfortunately, randomized clinical trials (RCTs) eliminate confounding but impose strict exclusion criteria that…

Machine Learning · Statistics 2021-06-15 Eric V. Strobl , Thomas A. Lasko

One central goal of design of observational studies is to embed non-experimental data into an approximate randomized controlled trial using statistical matching. Despite empirical researchers' best intention and effort to create…

Methodology · Statistics 2022-06-22 Kan Chen , Siyu Heng , Qi Long , Bo Zhang

Evaluating the computational reproducibility of data analysis pipelines has become a critical issue. It is, however, a cumbersome process for analyses that involve data from large populations of subjects, due to their computational and…

Methodology · Statistics 2018-09-28 Soudabeh Barghi , Lalet Scaria , Ali Salari , Tristan Glatard

Randomized controlled trials (RCTs) are the gold standard for evaluating causal effects but are often costly and difficult to scale; consequently, they are frequently augmented with auxiliary external controls in many applications. Prior…

Methodology · Statistics 2026-05-28 Jiawei Shan , Yiteng Tu , Guanbo Wang , Chao Ying , Jiwei Zhao

Deep reinforcement learning (DRL) has significantly advanced the field of combinatorial optimization (CO). However, its practicality is hindered by the necessity for a large number of reward evaluations, especially in scenarios involving…

Machine Learning · Computer Science 2024-07-18 Hyeonah Kim , Minsu Kim , Sungsoo Ahn , Jinkyoo Park

The weighted average treatment effect (WATE) is a causal measure for the comparison of interventions in a specific target population, which may be different from the population where data are sampled from. For instance, when the goal is to…

Methodology · Statistics 2018-04-17 Yebin Tao , Haoda Fu

Integrative analysis of datasets generated by multiple cohorts is a widely-used approach for increasing sample size, precision of population estimators, and generalizability of analysis results in epidemiological studies. However, often…

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