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Multimodal (MM) learning is emerging as a promising paradigm in biomedical artificial intelligence (AI) applications, integrating complementary modality, which highlight different aspects of patient health. The scarcity of large…

Artificial Intelligence · Computer Science 2025-12-01 Niccolo Marini , Zhaohui Liang , Sivaramakrishnan Rajaraman , Zhiyun Xue , Sameer Antani

Supervised machine learning (ML) is used extensively in biology and deserves closer scrutiny. The DOME recommendations aim to enhance the validation and reproducibility of ML research by establishing standards for key aspects such as data…

We present Open Ontologies, an open-source ontology engineering system implemented in Rust that integrates LLM-driven construction with formal OWL reasoning and ontology alignment via the Model Context Protocol. Our primary finding is that…

Artificial Intelligence · Computer Science 2026-05-12 Fabio Rovai

Optimization modeling plays a critical role in the application of Operations Research (OR) tools to address real-world problems, yet they pose challenges and require extensive expertise from OR experts. With the advent of large language…

Computation and Language · Computer Science 2025-07-30 Chenyu Huang , Zhengyang Tang , Shixi Hu , Ruoqing Jiang , Xin Zheng , Dongdong Ge , Benyou Wang , Zizhuo Wang

The Ontology Lookup Service (OLS) is an open source search engine for ontologies which is used extensively in the bioinformatics and chemistry communities to annotate biological and biomedical data with ontology terms. Recently there has…

Information Retrieval · Computer Science 2025-01-23 James McLaughlin , Josh Lagrimas , Haider Iqbal , Helen Parkinson , Henriette Harmse

Amid the recent uptake of Generative AI, sociotechnical scholars and critics have traced a multitude of resulting harms, with analyses largely focused on values and axiology (e.g., bias). While value-based analyses are crucial, we argue…

Human-Computer Interaction · Computer Science 2025-04-07 Nava Haghighi , Sunny Yu , James Landay , Daniela Rosner

We explore the role of ontologies in enhancing hybrid modeling and simulation through improved semantic rigor, model reusability, and interoperability across systems, disciplines, and tools. By distinguishing between methodological and…

Artificial Intelligence · Computer Science 2025-06-17 John Beverley , Andreas Tolk

Multi-omics studies often rely on pathway enrichment to interpret heterogeneous molecular changes, but pathway enrichment (PE)-based workflows inherit structural limitations of pathway resources, including curation lag, functional…

Computation and Language · Computer Science 2026-01-01 Sibo Wei , Peng Chen , Lifeng Dong , Yin Luo , Lei Wang , Peng Zhang , Wenpeng Lu , Jianbin Guo , Hongjun Yang , Dajun Zeng

Increasing evidence shows that flaws in machine learning (ML) algorithm validation are an underestimated global problem. Particularly in automatic biomedical image analysis, chosen performance metrics often do not reflect the domain…

In applied mathematics and related disciplines, the modeling-simulation-optimization workflow is a prominent scheme, with mathematical models and numerical algorithms playing a crucial role. For these types of mathematical research data,…

Earth Observation (EO) data encompass a vast range of remotely sensed information, featuring multi-sensor and multi-temporal, playing an indispensable role in understanding our planet's dynamics. Recently, Vision Language Models (VLMs) have…

Computer Vision and Pattern Recognition · Computer Science 2025-02-21 Xizhe Xue , Xiao Xiang Zhu

Clinical trial eligibility matching is a critical yet often labor-intensive and error-prone step in medical research, as it ensures that participants meet precise criteria for safe and reliable study outcomes. Recent advances in Natural…

Machine Learning · Computer Science 2025-03-04 Muhammad Talha Sharif , Abdul Rehman

This study defines a new evaluation metric for audio tagging tasks to overcome the limitation of the conventional mean average precision (mAP) metric, which treats different kinds of sound as independent classes without considering their…

Audio and Speech Processing · Electrical Eng. & Systems 2023-10-10 Haohe Liu , Qiuqiang Kong , Xubo Liu , Xinhao Mei , Wenwu Wang , Mark D. Plumbley

Ontology matching finds correspondences between similar entities of different ontologies. Two ontologies may be similar in some aspects such as structure, semantic etc. Most ontology matching systems integrate multiple matchers to extract…

Artificial Intelligence · Computer Science 2013-11-18 Mohammad Mehdi Keikha , Mohammad Ali Nematbakhsh , Behrouz Tork Ladani

Computational methods that operate on three-dimensional molecular structure have the potential to solve important questions in biology and chemistry. In particular, deep neural networks have gained significant attention, but their…

The European Materials and Modelling Ontology (EMMO) has recently been advanced in the computational molecular engineering and multiscale modelling communities as a top-level ontology, aiming to support semantic interoperability and data…

Artificial Intelligence · Computer Science 2021-02-12 Martin Thomas Horsch , Silvia Chiacchiera , Björn Schembera , Michael A. Seaton , Ilian T. Todorov

Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

Computation and Language · Computer Science 2024-05-27 Nicholas J Dobbins

High-dimensional omics data contains intrinsic biomedical information that is crucial for personalised medicine. Nevertheless, it is challenging to capture them from the genome-wide data due to the large number of molecular features and…

Genomics · Quantitative Biology 2021-06-22 Xiaoyu Zhang , Yuting Xing , Kai Sun , Yike Guo

Growth in computational materials science and initiatives such as the Materials Genome Initiative (MGI) and the European Materials Modelling Council (EMMC) has motivated the development and application of ontologies. A key factor has been…

Digital Libraries · Computer Science 2024-03-05 Scott McClellan , Yuan An , Xintong Zhao , Xia Lin , Jane Greenberg

AI-driven precision oncology has the transformative potential to reshape cancer treatment by leveraging the power of AI models to analyze the interaction between complex patient characteristics and their corresponding treatment outcomes.…