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We consider systems of slow--fast diffusions with small noise in the slow component. We construct provably logarithmic asymptotically optimal importance schemes for the estimation of rare events based on the moderate deviations principle.…

Probability · Mathematics 2020-01-07 Matthew R. Morse , Konstantinos Spiliopoulos

Large Genomic Foundation Models have recently achieved remarkable results and in-vivo translation capabilities. However these models quickly grow to over a few Billion of parameters and are expensive to run when compute is limited. To…

Machine Learning · Computer Science 2026-04-13 Rasched Haidari , Sam Martin , Maxime Allard

Probably the most fundamental processes for biological systems is their ability to create themselves through the use of cell division and cell differentiation. In this work a simple physical model is proposed for biological cell division.…

Biological Physics · Physics 2010-06-22 Eshel Faraggi

Time crystals are many-body systems whose ground state spontaneously breaks time-translation symmetry and thus exhibits long-range spatiotemporal order and robust periodic motion. Using hydrodynamics, we have recently shown how an…

Statistical Mechanics · Physics 2025-12-15 R. Hurtado-Gutiérrez , C. Pérez-Espigares , P. I. Hurtado

We review a few representative examples of granular experiments or models where phase separation, accompanied by domain coarsening, is a relevant phenomenon. We first elucidate the intrinsic non-equilibrium, or athermal, nature of granular…

Statistical Mechanics · Physics 2015-04-29 Andrea Baldassarri , Andrea Puglisi , Alessandro Sarracino

Liquid-liquid phase separation is an important mechanism for compartmentalizing the cell's cytoplasm, allowing the dynamic organization of the components necessary for survival. However, it is not clear how phase separation is affected by…

Soft Condensed Matter · Physics 2022-01-31 Estefania Vidal-Henriquez , David Zwicker

The ability to control the crystallization behaviour (including its absence) of particles, be they biomolecules such as globular proteins, inorganic colloids, nanoparticles, or metal atoms in an alloy, is of both fundamental and…

Order parameter fluctuations (the largest cluster size distribution) are studied within a three-dimensional bond percolation model on small lattices. Cumulant ratios measuring the fluctuations exhibit distinct features near the percolation…

Nuclear Theory · Physics 2007-05-23 Janusz Brzychczyk

Previous parallel sorting algorithms do not scale to the largest available machines, since they either have prohibitive communication volume or prohibitive critical path length. We describe algorithms that are a viable compromise and…

Data Structures and Algorithms · Computer Science 2015-02-26 Michael Axtmann , Timo Bingmann , Peter Sanders , Christian Schulz

Distilled diffusion models generate images in far fewer timesteps but suffer from reduced sample diversity when generating multiple outputs from the same prompt. To understand this phenomenon, we first investigate whether distillation…

Graphics · Computer Science 2025-11-11 Rohit Gandikota , David Bau

We propose a distillation scaling law that estimates distilled model performance based on a compute budget and its allocation between the student and teacher. Our findings mitigate the risks associated with large-scale distillation by…

Machine Learning · Computer Science 2025-07-28 Dan Busbridge , Amitis Shidani , Floris Weers , Jason Ramapuram , Etai Littwin , Russ Webb

This article focuses on phase and aggregation behavior for linear chains composed of blocks of hydrophilic and hydrophobic segments. Phase and conformational transitions of patterned chains are relevant for understanding liquid-liquid…

Soft Condensed Matter · Physics 2024-05-15 Athanassios Z. Panagiotopoulos

The work is devoted to the analysis of cell population dynamics where cells make a choice between differentiation and apoptosis. This choice is based on the values of intracellular proteins whose concentrations are described by a system of…

Cell Behavior · Quantitative Biology 2016-03-30 Malay Banerjee , Vitaly Volpert

Species or population that proliferate faster than others become dominant in numbers. Catalysis allows catalytic sets within a molecular reaction network to dominate the non catalytic parts of the network by processing most of the available…

Cell Behavior · Quantitative Biology 2016-08-31 Rudolf Hanel

Liesegang patterns emerge from precipitation processes and may be used to build bulk structures at submicron lengthscales. Thus they have significant potential for technological applications provided adequate methods of control can be…

Other Condensed Matter · Physics 2016-09-08 Tibor Antal , Ioana Bena , Michel Droz , Kirsten Martens , Zoltan Racz

We investigate the connections between microscopic chaos, defined on a dynamical level and arising from collisions between molecules, and diffusion, characterized by a mean square displacement proportional to the time. We use a number of…

Chaotic Dynamics · Physics 2007-05-23 C. P. Dettmann , E. G. D. Cohen

Cell membranes phase separate into ordered ${\rm L_o}$ and disordered ${\rm L_d}$ domains depending on their compositions. This membrane compartmentalization is heterogeneous and regulates the localization of specific proteins related to…

Soft Condensed Matter · Physics 2023-08-11 Ken Sakamoto , Takuma Akimoto , Mayu Muramatsu , Mark S. P. Sansom , Ralf Metzler , Eiji Yamamoto

A vector order parameter phase field model derived from a grand potential functional is presented as a new approach for modeling polycrystalline solidification of alloys. In this approach, the grand potential density is designed to contain…

Materials Science · Physics 2021-06-02 Tatu Pinomaa , Nana Ofori-Opoku , Anssi Laukkanen , Nikolas Provatas

Based on extensive study of a dynamical systems model of the development of a cell society, a novel theory for stem cell differentiation and its regulation is proposed as the ``chaos hypothesis''. Two fundamental features of stem cell…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Chikara Furusawa , Kunihiko Kaneko

This is a summarising investigation of the events of the phase transition of the first order that occur in the critical region below the liquid-gas critical point. The grand partition function has been completely integrated in the…

Statistical Mechanics · Physics 2015-01-13 I. R. Yukhnovskii
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