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The comparison of different medical treatments from observational studies or across different clinical studies is often biased by confounding factors such as systematic differences in patient demographics or in the inclusion criteria for…

Methodology · Statistics 2025-05-15 Ekkehard Glimm , Lillian Yau

A number of biomedical problems require performing many hypothesis tests, with an attendant need to apply stringent thresholds. Often the data take the form of a series of predictor vectors, each of which must be compared with a single…

Methodology · Statistics 2014-05-13 Yi-Hui Zhou , Fred Wright

Multiple hypothesis tests are often carried out in practice using p-value estimates obtained with bootstrap or permutation tests since the analytical p-values underlying all hypotheses are usually unknown. This article considers the…

Computation · Statistics 2019-10-08 Georg Hahn

Plausibility is a formalization of exact tests for parametric models and generalizes procedures such as Fisher's exact test. The resulting tests are based on cumulative probabilities of the probability density function and evaluate…

Statistics Theory · Mathematics 2021-09-13 Stefan Böhringer , Dietmar Lohmann

Let $\pi_n$ be a uniformly chosen random permutation on $[n]$. Using an analysis of the probability that two overlapping consecutive $k$-permutations are order isomorphic, the authors of a recent paper showed that the expected number of…

Combinatorics · Mathematics 2024-08-07 Anant Godbole , Hannah Swickheimer

Consider testing multiple hypotheses in the setting where the p-values of all hypotheses are unknown and thus have to be approximated using Monte Carlo simulations. One class of algorithms published in the literature for this scenario…

Statistics Theory · Mathematics 2020-06-16 Georg Hahn

A numerical technique is introduced that reduces exponentially the time required for Monte Carlo simulations of non-equilibrium systems. Results for the quasi-stationary probability distribution in two model systems are compared with the…

Adaptation and Self-Organizing Systems · Physics 2009-11-07 A. Bandrivskyy , S. Beri , D. G. Luchinsky , R. Mannella , P. V. E. McClintock

Model counting of Disjunctive Normal Form (DNF) formulas is a critical problem in applications such as probabilistic inference and network reliability. For example, it is often used for query evaluation in probabilistic databases. Due to…

Data Structures and Algorithms · Computer Science 2026-01-16 Paul Burkhardt , David G. Harris , Kevin T Schmitt

Probabilistic programming methods have revolutionised Bayesian inference, making it easier than ever for practitioners to perform Markov-chain-Monte-Carlo sampling from non-conjugate posterior distributions. Here we focus on Stan, arguably…

Computation · Statistics 2025-02-10 Clemens Pichler , Jack Jewson , Alejandra Avalos-Pacheco

Much algorithmic research in NLP aims to efficiently manipulate rich formal structures. An algorithm designer typically seeks to provide guarantees about their proposed algorithm -- for example, that its running time or space complexity is…

Programming Languages · Computer Science 2025-12-30 Tim Vieira , Ryan Cotterell , Jason Eisner

We consider statistical procedures for hypothesis testing of real valued functionals of matched pairs with missing values. In order to improve the accuracy of existing methods, we propose a novel multiplication combination procedure.…

Statistics Theory · Mathematics 2018-01-29 Lubna Amro , Frank Konietschke , Markus Pauly

To improve the efficiency of Monte Carlo estimation, practitioners are turning to biased Markov chain Monte Carlo procedures that trade off asymptotic exactness for computational speed. The reasoning is sound: a reduction in variance due to…

Machine Learning · Statistics 2019-01-03 Jackson Gorham , Lester Mackey

We consider the first problem that appears in any application of synchronizing automata, namely, the problem of deciding whether or not a given $n$-state $k$-letter automaton is synchronizing. First we generalize results from…

Formal Languages and Automata Theory · Computer Science 2019-03-20 Mikhail V. Berlinkov

Detecting and counting copies of permutation patterns are fundamental algorithmic problems, with applications in the analysis of rankings, nonparametric statistics, and property testing tasks such as independence and quasirandomness…

Data Structures and Algorithms · Computer Science 2026-05-07 Michal Opler

Clustering is at the very core of machine learning, and its applications proliferate with the increasing availability of data. However, as datasets grow, comparing clusterings with an adjustment for chance becomes computationally difficult,…

Machine Learning · Computer Science 2023-08-01 Kai Klede , Leo Schwinn , Dario Zanca , Björn Eskofier

Considering multivariate strongly mixing time series, nonparametric tests for a constant copula with specified or unspecified change point (candidate) are derived; the tests are consistent against general alternatives. A tapered block…

Statistics Theory · Mathematics 2012-06-11 Axel Bücher , Martin Ruppert

Experimental comparisons of performance represent an important aspect of research on optimization algorithms. In this work we present a methodology for defining the required sample sizes for designing experiments with desired statistical…

Neural and Evolutionary Computing · Computer Science 2018-10-16 Felipe Campelo , Fernanda Takahashi

The robust rank-order test (Fligner and Policello, 1981) was designed as an improvement of the non-parametric Wilcoxon-Mann-Whitney U-test to be more appropriate when the samples being compared have unequal variance. However, it tends to be…

Methodology · Statistics 2020-09-08 Nirvik Sinha

Given independent samples from P and Q, two-sample permutation tests allow one to construct exact level tests when the null hypothesis is P=Q. On the other hand, when comparing or testing particular parameters $\theta$ of P and Q, such as…

Statistics Theory · Mathematics 2013-04-23 EunYi Chung , Joseph P. Romano

Monte Carlo methods can provide accurate p-value estimates of word counting test statistics and are easy to implement. They are especially attractive when an asymptotic theory is absent or when either the search sequence or the word pattern…

Applications · Statistics 2008-12-01 Hock Peng Chan , Nancy R. Zhang , Louis H. Y. Chen