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Reliable cell segmentation and classification from biomedical images is a crucial step for both scientific research and clinical practice. A major challenge for more robust segmentation and classification methods is the large variations in…

Cell Behavior · Quantitative Biology 2017-10-31 Mo Zhang , Xiang Li , Mengjia Xu , Quanzheng Li

The need for labour intensive pixel-wise annotation is a major limitation of many fully supervised learning methods for segmenting bioimages that can contain numerous object instances with thin separations. In this paper, we introduce a…

Computer Vision and Pattern Recognition · Computer Science 2020-09-11 Rihuan Ke , Aurélie Bugeau , Nicolas Papadakis , Peter Schuetz , Carola-Bibiane Schönlieb

Microfluidic devices offer numerous advantages in medical applications, including the capture of single cells in microwell-based platforms for genomic analysis. As the cost of sequencing decreases, the demand for high-throughput single-cell…

Computational Engineering, Finance, and Science · Computer Science 2024-09-13 Xueying Zhao , Yan Chen , Yuefu Jiang , Amie Radenbaugh , Jamie Moskwa , Devon Jensen

Additively manufactured metals exhibit heterogeneous microstructure which dictates their material and failure properties. Experimental microstructural characterization techniques generate a large amount of data that requires expensive…

Image and Video Processing · Electrical Eng. & Systems 2021-05-10 Roberto Perera , Davide Guzzetti , Vinamra Agrawal

While robotic manipulation of rigid objects is quite straightforward, coping with deformable objects is an open issue. More specifically, tasks like tying a knot, wiring a connector or even surgical suturing deal with the domain of…

Computer Vision and Pattern Recognition · Computer Science 2018-10-11 Daniele De Gregorio , Gianluca Palli , Luigi Di Stefano

Accurate segmentation of the blood vessels of the retina is an important step in clinical diagnosis of ophthalmic diseases. Many deep learning frameworks have come up for retinal blood vessels segmentation tasks. However, the complex…

Image and Video Processing · Electrical Eng. & Systems 2022-04-08 Ting Zhang , Jun Li , Yi Zhao , Nan Chen , Han Zhou , Hongtao Xu , Zihao Guan , Changcai Yang , Lanyan Xue , Riqing Chen , Lifang Wei

Computer vision techniques have advanced significantly in recent years, finding diverse and impactful applications within the medical field. In this paper, we introduce a new framework for the detection of Bethesda cells in Pap smear…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Martin Amster , Camila María Polotto

Fluorescence microscopy has become a widely used tool for studying various biological structures of in vivo tissue or cells. However, quantitative analysis of these biological structures remains a challenge due to their complexity which is…

Computer Vision and Pattern Recognition · Computer Science 2019-04-16 Soonam Lee , Chichen Fu , Paul Salama , Kenneth W. Dunn , Edward J. Delp

Object detection is of paramount importance in biomedical image analysis, particularly for lesion identification. While current methodologies are proficient in identifying and pinpointing lesions, they often lack the precision needed to…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Zilin Chen , Shengnan Lu

Malignant lymphoma subtype classification directly impacts treatment strategies and patient outcomes, necessitating classification models that achieve both high accuracy and sufficient explainability. This study proposes a novel explainable…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Daiki Nishiyama , Hiroaki Miyoshi , Noriaki Hashimoto , Koichi Ohshima , Hidekata Hontani , Ichiro Takeuchi , Jun Sakuma

Unsupervised object discovery aims to localize objects in images, while removing the dependence on annotations required by most deep learning-based methods. To address this problem, we propose a fully unsupervised, bottom-up approach, for…

Computer Vision and Pattern Recognition · Computer Science 2022-12-21 Sandra Kara , Hejer Ammar , Florian Chabot , Quoc-Cuong Pham

Localization of single fluorescent molecules is key for physicochemical and biophysical measurements such as single-molecule tracking and super-resolution imaging by single-molecule localization microscopy (SMLM). Recently a series of…

Optics · Physics 2021-09-06 Luciano A. Masullo , Lucía F. Lopez , Fernando D. Stefani

Automating classification and segmentation process of abnormal regions in different body organs has a crucial role in most of medical imaging applications such as funduscopy, endoscopy, and dermoscopy. Detecting multiple abnormalities in…

Computer Vision and Pattern Recognition · Computer Science 2018-10-17 Mohsen Hajabdollahi , Reza Esfandiarpoor , Elyas Sabeti , Nader Karimi , Kayvan Najarian , S. M. Reza Soroushmehr , Shadrokh Samavi

Recent object detection systems rely on two critical steps: (1) a set of object proposals is predicted as efficiently as possible, and (2) this set of candidate proposals is then passed to an object classifier. Such approaches have been…

Computer Vision and Pattern Recognition · Computer Science 2015-09-02 Pedro O. Pinheiro , Ronan Collobert , Piotr Dollar

Object detection has been a challenging task in computer vision. Although significant progress has been made in object detection with deep neural networks, the attention mechanism is far from development. In this paper, we propose the…

Computer Vision and Pattern Recognition · Computer Science 2020-02-19 Ya-Li Li , Shengjin Wang

Owing to a large amount of multi-modal data in modern medical systems, such as medical images and reports, Medical Vision-Language Pre-training (Med-VLP) has demonstrated incredible achievements in coarse-grained downstream tasks (i.e.,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Weiwei Tian , Xinyu Huang , Junlin Hou , Caiyue Ren , Longquan Jiang , Rui-Wei Zhao , Gang Jin , Yuejie Zhang , Daoying Geng

Automated detection of grain boundaries (GBs) in electron microscope images of polycrystalline materials could help accelerate the nanoscale characterization of myriad engineering materials and novel materials under scientific research.…

Materials Science · Physics 2025-11-06 Doruk Aksoy , Huolin L. Xin , Timothy J. Rupert , William J. Bowman

Estimating the trajectories of multi-objects poses a significant challenge due to data association ambiguity, which leads to a substantial increase in computational requirements. To address such problems, a divide-and-conquer manner has…

Signal Processing · Electrical Eng. & Systems 2023-10-24 Ji Youn Lee , Changbeom Shim , Hoa Van Nguyen , Tran Thien Dat Nguyen , Hyunjin Choi , Youngho Kim

In this paper we propose a novel deep learning-based algorithm for biomedical image segmentation which uses a sequential attention mechanism able to shift the focus of attention across the image in a selective way, allowing subareas which…

Computer Vision and Pattern Recognition · Computer Science 2019-09-30 Shohei Hayashi , Bisser Raytchev , Toru Tamaki , Kazufumi Kaneda

Multi-modal learning is typically performed with network architectures containing modality-specific layers and shared layers, utilizing co-registered images of different modalities. We propose a novel learning scheme for unpaired…

Computer Vision and Pattern Recognition · Computer Science 2020-01-10 Qi Dou , Quande Liu , Pheng Ann Heng , Ben Glocker
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