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Microscopy imaging techniques are instrumental for characterization and analysis of biological structures. As these techniques typically render 3D visualization of cells by stacking 2D projections, issues such as out-of-plane excitation and…

Image and Video Processing · Electrical Eng. & Systems 2023-02-16 Amirkoushyar Ziabari , Derek C. Rose , Abbas Shirinifard , David Solecki

Cell segmentation is a critical step for quantitative single-cell analysis in microscopy images. Existing cell segmentation methods are often tailored to specific modalities or require manual interventions to specify hyper-parameters in…

Cell segmentation for multi-modal microscopy images remains a challenge due to the complex textures, patterns, and cell shapes in these images. To tackle the problem, we first develop an automatic cell classification pipeline to label the…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Wei Lou , Xinyi Yu , Chenyu Liu , Xiang Wan , Guanbin Li , Siqi Liu , Haofeng Li

In biomedical imaging reliable segmentation of objects (e.g. from small cells up to large organs) is of fundamental importance for automated medical diagnosis. New approaches for multi-scale segmentation can considerably improve performance…

Numerical Analysis · Mathematics 2016-10-04 Leonie Zeune , Guus van Dalum , Leon W. M. M. Terstappen , S. A. van Gils , Christoph Brune

The spread of microbial infections is governed by the self-organization of bacteria on surfaces. Limitations of live imaging techniques make collective behaviors in clinically relevant systems challenging to quantify. Here, novel…

Biological Physics · Physics 2024-07-19 Vincent Hickl , Abid Khan , René M. Rossi , Bruno F. B. Silva , Katharina Maniura-Weber

Complete blood cell detection holds significant value in clinical diagnostics. Conventional manual microscopy methods suffer from time inefficiency and diagnostic inaccuracies. Existing automated detection approaches remain constrained by…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Guohua Wu , Shengqi Chen , Pengchao Deng , Wenting Yu

Detecting and segmenting individual cells from microscopy images is critical to various life science applications. Traditional cell segmentation tools are often ill-suited for applications in brightfield microscopy due to poor contrast and…

Image and Video Processing · Electrical Eng. & Systems 2020-05-20 Rituparna Sarkar , Suvadip Mukherjee , Elisabeth Labruyère , Jean-Christophe Olivo-Marin

We present MBIS (Multivariate Bayesian Image Segmentation tool), a clustering tool based on the mixture of multivariate normal distributions model. MBIS supports multi-channel bias field correction based on a B-spline model. A second…

Computer Vision and Pattern Recognition · Computer Science 2015-11-19 Oscar Esteban , Gert Wollny , Subrahmanyam Gorthi , Maria-J. Ledesma-Carbayo , Jean-Philippe Thiran , Andres Santos , Meritxell Bach-Cuadra

In the detection of myeloproliferative, the number of cells in each type of bone marrow cells (BMC) is an important parameter for the evaluation. In this study, we propose a new counting method, which also consists of three modules…

Computer Vision and Pattern Recognition · Computer Science 2018-05-08 Haichao Cao , Hong Liu , Enmin Song

This paper presents a novel approach for multi-kernel estimation by enhancing the KernelGAN algorithm, which traditionally estimates a single kernel for the entire image. We introduce Multi-KernelGAN, which extends KernelGAN's capabilities…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Haim Goldfisher , Asaf Yekutiel

Object detection and semantic segmentation are pivotal components in biomedical image analysis. Current single-task networks exhibit promising outcomes in both detection and segmentation tasks. Multi-task networks have gained prominence due…

Computer Vision and Pattern Recognition · Computer Science 2024-03-04 Suizhi Huang , Shalayiding Sirejiding , Yuxiang Lu , Yue Ding , Leheng Liu , Hui Zhou , Hongtao Lu

This paper introduces a comprehensive approach for segmenting regions of interest (ROI) in diverse medical imaging datasets, encompassing ultrasound, CT scans, and X-ray images. The proposed method harnesses the capabilities of the YOLOv8…

Computer Vision and Pattern Recognition · Computer Science 2023-10-23 Sumit Pandey , Kuan-Fu Chen , Erik B. Dam

Cell segmentation is a fundamental task for computational biology analysis. Identifying the cell instances is often the first step in various downstream biomedical studies. However, many cell segmentation algorithms, including the recently…

Computer Vision and Pattern Recognition · Computer Science 2022-12-08 Gihun Lee , Sangmook Kim , Joonkee Kim , Se-Young Yun

Tracking many cells in time-lapse 3D image sequences is an important challenging task of bioimage informatics. Motivated by a study of brain-wide 4D imaging of neural activity in C. elegans, we present a new method of multi-cell tracking.…

Computer Vision and Pattern Recognition · Computer Science 2018-01-18 Osamu Hirose , Shotaro Kawaguchi , Terumasa Tokunaga , Yu Toyoshima , Takayuki Teramoto , Sayuri Kuge , Takeshi Ishihara , Yuichi Iino , Ryo Yoshida

Multi-organ segmentation, which identifies and separates different organs in medical images, is a fundamental task in medical image analysis. Recently, the immense success of deep learning motivated its wide adoption in multi-organ…

Computer Vision and Pattern Recognition · Computer Science 2023-04-17 Jiahua Dong , Guohua Cheng , Yue Zhang , Chengtao Peng , Yu Song , Ruofeng Tong , Lanfen Lin , Yen-Wei Chen

Wood comprises different cell types, such as fibers, tracheids and vessels, defining its properties. Studying cells' shape, size, and arrangement in microscopy images is crucial for understanding wood characteristics. Typically, this…

Computer Vision and Pattern Recognition · Computer Science 2024-06-19 Saqib Qamar , Abu Imran Baba , Stéphane Verger , Magnus Andersson

Two successful approaches for the segmentation of biomedical images are (1) the selection of segment candidates from a merge-tree, and (2) the clustering of small superpixels by solving a Multi-Cut problem. In this paper, we introduce a…

Computer Vision and Pattern Recognition · Computer Science 2017-07-05 Jan Funke , Chong Zhang , Tobias Pietzsch , Stephan Saalfeld

Segmentation is a key stage in dermoscopic image processing, where the accuracy of the border line that defines skin lesions is of utmost importance for subsequent algorithms (e.g., classification) and computer-aided early diagnosis of…

Computer Vision and Pattern Recognition · Computer Science 2019-02-21 Pedro M. M. Pereira , Rui Fonseca-Pinto , Rui Pedro Paiva , Luis M. N. Tavora , Pedro A. A. Assuncao , Sergio M. M. de Faria

Manual segmentation of medical images (e.g., segmenting tumors in CT scans) is a high-effort task that can be accelerated with machine learning techniques. However, selecting the right segmentation approach depends on the evaluation…

Computer Vision and Pattern Recognition · Computer Science 2023-02-09 Seyed M. R. Modaresi , Aomar Osmani , Mohammadreza Razzazi , Abdelghani Chibani

The objective of this paper is a model that is able to discover, track and segment multiple moving objects in a video. We make four contributions: First, we introduce an object-centric segmentation model with a depth-ordered layer…

Computer Vision and Pattern Recognition · Computer Science 2022-11-15 Junyu Xie , Weidi Xie , Andrew Zisserman
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