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Visualization of the in vivo spatial distribution of superparamagnetic iron oxide nanoparticles (SPIONs) is crucial to biomedicine. Magnetic particle imaging (MPI) is one of the most promising approaches for direct measurements of the SPION…

Medical Physics · Physics 2022-07-13 Klaas-Julian Janssen , Meinhard Schilling , Frank Ludwig , Jing Zhong

Magnetic Particle Imaging (MPI) has been shown to provide remarkable contrast for imaging applications such as angiography, stem cell tracking, and cancer imaging. Recently, there is growing interest in the functional imaging capabilities…

Medical Physics · Physics 2017-04-26 Mustafa Utkur , Yavuz Muslu , Emine Ulku Saritas

Magnetic particle imaging (MPI) is an emerging medical imaging modality which offers a unique combination of high temporal and spatial resolution, sensitivity and biocompatibility. For system-matrix (SM) based image reconstruction in MPI, a…

Software Engineering · Computer Science 2024-01-12 Anselm von Gladiss , Amir Shayan Ahmadian , Jan Jürjens

In Magnetic Particle Imaging (MPI), it is typically assumed that the studied specimen is stationary during the data acquisition. In practical applications however, the searched-for 3D distribution of the magnetic nanoparticles might show a…

Optimization and Control · Mathematics 2024-01-26 Marius Nitzsche , Bernadette N Hahn

Magnetic particle imaging (MPI) is a tracer-based imaging modality that detects superparamagnetic iron oxide nanoparticles in vivo, with applications in cancer cell tracking, lymph node mapping, and cell therapy monitoring. We introduce a…

Magnetic Particle Imaging is an emerging imaging modality through which it is possible to detect tracers containing superparamagnetic nanoparticles. The exposure of the particles to dynamic magnetic fields generates a non-linear response…

Numerical Analysis · Mathematics 2024-06-19 Vladyslav Gapyak , Thomas März , Andreas Weinmann

Magnetic Particle Imaging (MPI) is an emerging imaging modality based on the magnetic response of superparamagnetic iron oxide nanoparticles to achieve high-resolution and real-time imaging without harmful radiation. One key challenge in…

Numerical Analysis · Mathematics 2025-01-13 Meira Iske , Hannes Albers , Tobias Knopp , Tobias Kluth

Magnetic Particle Imaging (MPI) is an emerging medical imaging modality that images the spatial distribution of superparamagnetic iron oxide (SPIO) nanoparticles using their nonlinear response to applied magnetic fields. In standard x-space…

Medical Physics · Physics 2019-12-11 Semih Kurt , Yavuz Muslu , Emine Ulku Saritas

Magnetic Particle Imaging (MPI) is a novel medical imaging modality. One of the established methods for MPI reconstruction is based on the System Matrix (SM). However, the calibration of the SM is often time-consuming and requires repeated…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Xuqing Geng , Lei Su , Zhongwei Bian , Zewen Sun , Jiaxuan Wen , Jie Tian , Yang Du

MALDI mass spectrometry imaging (MALDI MSI) is a spatially resolved analytical tool for biological tissue analysis by measuring mass-to-charge ratios of ionized molecules. With increasing spatial and mass resolution of MALDI MSI data,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-04 Florian Lieb , Tobias Boskamp , Hans-Georg Stark

Magnetic Particle Imaging (MPI) is a promising noninvasive in vivo imaging modality that makes it possible to map the spatial distribution of superparamagnetic nanoparticles by exposing them to dynamic magnetic fields. In the Field-Free…

Numerical Analysis · Mathematics 2025-08-08 Vladyslav Gapyak , Thomas März , Andreas Weinmann

Magnetic Particle Imaging (MPI) has been successfully used to visualize the distribution of superparamagnetic nanoparticles within 3D volumes with high sensitivity in real time. Since the magnetic field topology of MPI scanners is well…

Magnetic particle imaging (MPI) is an emerging imaging technique with many applications and a very active field of research. This app provides users with the opportunity to develop some intuition about the inner workings of MPI as it is…

Instrumentation and Detectors · Physics 2024-08-09 The-Vinh Tran-Luu , Mark-Alexander Henn , Klaus N. Quelhas , Solomon I. Woods

Magnetic Particle Imaging (MPI) is an emerging imaging modality that maps the spatial distribution of magnetic nanoparticles. The x-space reconstruction in MPI results in highly blurry images, where the resolution depends on both system…

Medical Physics · Physics 2020-01-31 Onur Yorulmaz , Omer Burak Demirel , Yavuz Muslu , Tolga Çukur , Emine U Saritas , A Enis Çetin

Magnetic Particle Imaging (MPI) is a promising imaging modality that tracks magnetic nanoparticles (MNPs) to generate real time, high-resolution images. However, achieving an optimal balance between strong signal strength and sharp image…

Medical Physics · Physics 2025-12-18 Abuobaida M. khair , Wenjing Jiang , Moritz Wildgruber , Wenjun Xi , Xiaopeng Ma

Purpose: To develop a general framework for Parallel Imaging (PI) with the use of Maxwell regularization for the estimation of the sensitivity maps (SMs) and constrained optimization for the parameter-free image reconstruction. Theory and…

Image and Video Processing · Electrical Eng. & Systems 2020-08-21 Matteo Alessandro Francavilla , Stamatios Lefkimmiatis , Jorge F. Villena , Athanasios G. Polimeridis

Magnetic nanoparticles (MNPs) play an important role in biomedical applications including imaging modalities such as MRI and magnetic particle imaging (MPI). The latter one exploits the non-linear magnetization response of a large ensemble…

Mesoscale and Nanoscale Physics · Physics 2021-10-27 Hannes Albers , Tobias Knopp , Martin Möddel , Marija Boberg , Tobias Kluth

Magnetic Particle Imaging (MPI) is a promising tomographic technique for visualizing the spatio-temporal distribution of superparamagnetic nanoparticles, with applications ranging from cancer detection to real-time cardiovascular…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Vladyslav Gapyak , Thomas März , Andreas Weinmann

Magnetic particle imaging (MPI) is a tracer-based technique that directly detects the distribution of magnetic iron-oxide nanoparticles with millisecond temporal resolution and no tissue background. Despite extensive preclinical work,…

Objective. Magnetic Particle Imaging (MPI) is capable of high temporal resolution measurements of the spatial distribution of magnetic nanoparticles and therefore well suited for perfusion imaging, which is an important tool in medical…