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Recent analyses combining advanced theoretical techniques and high-quality data from thousands of simultaneously recorded neurons provide strong support for the hypothesis that neural dynamics operate near the edge of instability across…

Neurons and Cognition · Quantitative Biology 2024-03-25 Rubén Calvo , Carles Martorell , Guillermo B. Morales , Serena Di Santo , Miguel A. Muñoz

The correlated variability in the responses of a neural population to the repeated presentation of a sensory stimulus is a universally observed phenomenon. Such correlations have been studied in much detail, both with respect to their…

Neurons and Cognition · Quantitative Biology 2018-07-04 Volker Pernice , Rava Azeredo da Silveira

Analysis of structural and functional connectivity (FC) of human brains is of pivotal importance for diagnosis of cognitive ability. The Human Connectome Project (HCP) provides an excellent source of neural data across different regions of…

Applications · Statistics 2020-07-10 Satwik Acharyya , Zhengwu Zhang , Anirban Bhattacharya , Debdeep Pati

We examine whether a single biophysical cortical circuit model can explain both spiking and perceptual variability. We consider perceptual rivalry, which provides a window into intrinsic neural processing since neural activity in some brain…

Neurons and Cognition · Quantitative Biology 2018-11-20 Benjamin P Cohen , Carson C Chow , Shashaank Vattikuti

Spiking neural network is a type of artificial neural network in which neurons communicate between each other with spikes. Spikes are identical Boolean events characterized by the time of their arrival. A spiking neuron has internal…

Neural and Evolutionary Computing · Computer Science 2016-02-16 Oleg Y. Sinyavskiy

Neuromorphic computing and spiking neural networks (SNN) mimic the behavior of biological systems and have drawn interest for their potential to perform cognitive tasks with high energy efficiency. However, some factors such as temporal…

Hardware Architecture · Computer Science 2021-05-10 Haowen Fang , Brady Taylor , Ziru Li , Zaidao Mei , Hai Li , Qinru Qiu

Since the first recordings made of evoked action potentials it has become apparent that the responses of individual neurons to ongoing physiologically relevant input, are highly variable. This variability is manifested in non-stationary…

Neurons and Cognition · Quantitative Biology 2010-08-10 Avner Wallach , Danny Eytan , Asaf Gal , Christoph Zrenner , Ron Meir , Shimon Marom

An essential step toward understanding neural circuits is linking their structure and their dynamics. In general, this relationship can be almost arbitrarily complex. Recent theoretical work has, however, begun to identify some broad…

Neurons and Cognition · Quantitative Biology 2017-03-10 Gabriel Koch Ocker , Yu Hu , Michael A. Buice , Brent Doiron , Krešimir Josić , Robert Rosenbaum , Eric Shea-Brown

In this paper we present an information theoretic approach to stochastic optimal control problems for systems with compound Poisson noise. We generalize previous work on information theoretic path integral control to discontinuous dynamics…

Optimization and Control · Mathematics 2019-07-03 Ziyi Wang , Grady Williams , Evangelos A. Theodorou

Multiscale modelling presents a multifaceted perspective into understanding the mechanisms of the brain and how neurodegenerative disorders like Parkinson's disease (PD) manifest and evolve over time. In this study, we propose a novel…

Neurons and Cognition · Quantitative Biology 2025-09-18 Aaron Herrera , Hina Shaheen

Understanding the dynamics of neural networks is a major challenge in experimental neuroscience. For that purpose, a modelling of the recorded activity that reproduces the main statistics of the data is required. In a first part, we present…

Neurons and Cognition · Quantitative Biology 2014-04-15 Hassan Nasser , Olivier Marre , Bruno Cessac

Neural population activity often exhibits regime-dependent non-stationarity in the form of switching dynamics. Learning accurate switching dynamical system models can reveal how behavior is encoded in neural activity. Existing switching…

Machine Learning · Computer Science 2025-12-16 DongKyu Kim , Han-Lin Hsieh , Maryam M. Shanechi

The aim of a number of psychophysics tasks is to uncover how mammals make decisions in a world that is in flux. Here we examine the characteristics of ideal and near-ideal observers in a task of this type. We ask when and how performance…

Neurons and Cognition · Quantitative Biology 2019-10-10 Adrian E. Radillo , Alan Veliz-Cuba , Krešimir Josić , Zachary P. Kilpatrick

We address the problem of finding patterns from multi-neuronal spike trains that give us insights into the multi-neuronal codes used in the brain and help us design better brain computer interfaces. We focus on the synchronous firings of…

Neural and Evolutionary Computing · Computer Science 2010-06-09 Raajay Viswanathan , P. S. Sastry , K. P. Unnikrishnan

Biological systems use neural circuits to integrate input information and produce outputs. Synaptic convergence, where multiple neurons converge their inputs onto a single downstream neuron, is common in natural neural circuits. However,…

Mesoscale and Nanoscale Physics · Physics 2026-02-04 Wendy Otieno , Alex Gabbitas , Debi Pattnaik , Pavel Borisov , Sergey Savel'ev , Alexander G. Balanov

The motor cortex (MC) is often described as an autonomous dynamical system during movement execution. In an autonomous dynamical system, flexible movement generation depends on reconfiguring the initial conditions, which then unwind along…

Neurons and Cognition · Quantitative Biology 2025-11-10 Fei Yin , Charles Guan , Tyson Aflalo , Jorge Gamez , Kelsie Pejsa , Emily Rosario , Charles Liu , Ausaf Bari , Richard Andersen

We introduce and analyze a class of neural network models motivated by the Drosophila central complex nervous system, designed to capture the emergence and dynamics of orientation-selective activity bumps. Starting from a biologically…

Dynamical Systems · Mathematics 2026-04-22 S. Ismail , B. Ambrosio , M. A. Aziz-Alaoui , Y. Souleiman

Experimental fMRI studies have shown that spontaneous brain activity i.e. in the absence of any external input, exhibit complex spatial and temporal patterns of co-activity between segregated brain regions. These so-called large-scale…

Adaptation and Self-Organizing Systems · Physics 2015-06-23 Vesna Vuksanović , Philipp Hövel

Brain-inspired machine intelligence research seeks to develop computational models that emulate the information processing and adaptability that distinguishes biological systems of neurons. This has led to the development of spiking neural…

Neural and Evolutionary Computing · Computer Science 2024-10-28 Alexander Ororbia

Measured responses from visual cortical neurons show that spike times tend to be correlated rather than exactly Poisson distributed. Fano factors vary and are usually greater than 1 due to the tendency of spikes being clustered into bursts.…

Neurons and Cognition · Quantitative Biology 2007-05-23 Alexander Lerchner , Mandana Ahmadi , John Hertz