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Population dynamics with complex biological interactions, accounting for uncertainty quantification, is critical for many application areas. However, due to the complexity of biological systems, the mathematical formulation of the…

Dynamical Systems · Mathematics 2022-06-20 Thi Kim Thoa Thieu , Adrian Muntean , Roderick Melnik

Machine learning models often require large datasets and struggle to generalize beyond their training distribution. These limitations pose significant challenges in scientific and engineering contexts, where generating exhaustive datasets…

Chemical Physics · Physics 2025-06-12 Salman N. Salman , Sergey A. Shteingolts , Ron Levie , Dan Mendels

In this paper we address the question of statistical model selection for a class of stochastic models of biological neural nets. Models in this class are systems of interacting chains with memory of variable length. Each chain describes the…

Statistics Theory · Mathematics 2018-12-19 A. Duarte , A. Galves , E. Löcherbach , G. Ost

Objective. Precise control of neural systems is essential to experimental investigations of how the brain controls behavior and holds the potential for therapeutic manipulations to correct aberrant network states. Model predictive control,…

Neurons and Cognition · Quantitative Biology 2024-08-06 Christof Fehrman , C. Daniel Meliza

This work analyzes fractional continuous-time random walks on two-layer multiplexes. A node-centric dynamics is used, in which it is assumed a Poisson distribution of a walker to become active, while a jump to one of its neighbors depends…

Physics and Society · Physics 2020-01-29 Alfonso Allen-Perkins , Roberto F. S. Andrade

Analysing biological spiking neural network models with synaptic plasticity has proven to be challenging both theoretically and numerically. In a network with N all-to-all connected neurons, the number of synaptic connections is on the…

Biological Physics · Physics 2025-10-06 Pascal Helson , Etienne Tanré , Romain Veltz

Motivated by the celebrated discrete-time model of nervous activity outlined by McCulloch and Pitts in 1943, we propose a novel continuous-time model, the McCulloch-Pitts network (MPN), for sequence learning in spiking neural networks. Our…

Disordered Systems and Neural Networks · Physics 2022-01-28 Zuozhu Liu , Thiparat Chotibut , Christopher Hillar , Shaowei Lin

Piecewise-deterministic Markov processes combine continuous in time dynamics with jump events, the rates of which generally depend on the continuous variables and thus are not constants. This leads to a problem in a Monte-Carlo simulation…

Computational Physics · Physics 2025-01-14 Arkady Pikovsky

Spike-timing-dependent plasticity(STDP) is a biological process of synaptic modification caused by the difference of firing order and timing between neurons. One of the neurodynamical roles of STDP is to form a macroscopic geometrical…

Neurons and Cognition · Quantitative Biology 2021-08-10 Hong-Gyu Yoon , Pilwon Kim

Contemporary modeling approaches to the dynamics of neural networks consider two main classes of models: biologically grounded spiking neurons and functionally inspired rate-based units. The unified simulation framework presented here…

Neurons and Cognition · Quantitative Biology 2017-11-27 Jan Hahne , David Dahmen , Jannis Schuecker , Andreas Frommer , Matthias Bolten , Moritz Helias , Markus Diesmann

Probabilistic approaches for handling count-valued time sequences have attracted amounts of research attentions because their ability to infer explainable latent structures and to estimate uncertainties, and thus are especially suitable for…

Machine Learning · Computer Science 2024-05-24 Jiahao Wang , Sikun Yang , Heinz Koeppl , Xiuzhen Cheng , Pengfei Hu , Guoming Zhang

A steadily increasing body of evidence suggests that the brain performs probabilistic inference to interpret and respond to sensory input and that trial-to-trial variability in neural activity plays an important role. The neural sampling…

Neurons and Cognition · Quantitative Biology 2017-07-07 Ilja Bytschok , Dominik Dold , Johannes Schemmel , Karlheinz Meier , Mihai A. Petrovici

We present Intermittent Control (IC) models as a candidate framework for modelling human input movements in Human--Computer Interaction (HCI). IC differs from continuous control in that users are not assumed to use feedback to adjust their…

Human-Computer Interaction · Computer Science 2021-03-16 J. Alberto Álvarez Martín , Henrik Gollee , Jörg Müller , Roderick Murray-Smith

Understanding the interaction patterns among simultaneous recordings of spike trains from multiple neuronal units is a key topic in neuroscience. However, an optimal approach of assessing these interactions has not been established, as…

Neurons and Cognition · Quantitative Biology 2020-12-17 Gorana Mijatovic , Yuri Antonacci , Tatjana Loncar-Turukalo , Ludovico Minati , Luca Faes

Experiments show that spike-triggered stimulation performed with Bidirectional Brain-Computer-Interfaces (BBCI) can artificially strengthen connections between separate neural sites in motor cortex (MC). What are the neuronal mechanisms…

Neurons and Cognition · Quantitative Biology 2017-04-12 Guillaume Lajoie , Nedialko I. Krouchev , John F. Kalaska , Adrienne L. Fairhall , Eberhard E. Fetz

Neurons subject to a common non-stationary input may exhibit a correlated firing behavior. Correlations in the statistics of neural spike trains also arise as the effect of interaction between neurons. Here we show that these two situations…

Quantitative Methods · Quantitative Biology 2021-04-13 Joanna Tyrcha , Yasser Roudi , Matteo Marsili , John Hertz

Demystifying effective connectivity among neuronal populations has become the trend to understand the brain mechanisms of Parkinson's disease, schizophrenia, mild traumatic brain injury, and many other unlisted neurological diseases.…

Quantitative Methods · Quantitative Biology 2019-09-27 Po-Ya Hsu

The population model of Wilson-Cowan is perhaps the most popular in the history of computational neuroscience. It embraces the nonlinear mean field dynamics of excitatory and inhibitory neuronal populations provided via a temporal…

Neurons and Cognition · Quantitative Biology 2023-09-13 Maryam Saadati , Saba Sadat Khodaei , Yousef Jamali

Nonlinear dynamics of spiking neural networks has recently attracted much interest as an approach to understand possible information processing in the brain and apply it to artificial intelligence. Since information can be processed by…

Spontaneous neural activity, crucial in memory, learning, and spatial navigation, often manifests itself as repetitive spatiotemporal patterns. Despite their importance, analyzing these patterns in large neural recordings remains…

Signal Processing · Electrical Eng. & Systems 2024-05-15 Roman Koshkin , Tomoki Fukai
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