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Understanding the rules underlying organismal development is a major unsolved problem in biology. Each cell in a developing organism responds to signals in its local environment by dividing, excreting, consuming, or reorganizing, yet how…

Cell Behavior · Quantitative Biology 2025-08-20 Ramya Deshpande , Francesco Mottes , Ariana-Dalia Vlad , Michael P. Brenner , Alma dal Co

We introduce and analyze several aspects of a new model for cell differentiation. It assumes that differentiation of progenitor cells is a continuous process. From the mathematical point of view, it is based on partial differential…

Analysis of PDEs · Mathematics 2013-01-21 Marie Doumic , Anna Marciniak-Czochra , Benoit Perthame , Jorge P. Zubelli

The regulation of the cell state is a complex process involving several components. These complex dynamics can be modeled using Boolean networks, allowing us to explain the existence of different cell states and the transition between them.…

Molecular Networks · Quantitative Biology 2010-01-28 Elke K. Markert , Nils Baas , Arnold J. Levine , Alexei Vazquez

Our knowledge of how individual cells self-organize to form complex multicellular systems is being revolutionized by a data outburst, coming from high-throughput experimental breakthroughs such as single-cell RNA sequencing and spatially…

Cell Behavior · Quantitative Biology 2021-04-20 Gabriel Torregrosa , Jordi Garcia-Ojalvo

Inspired by the quest for shape-shifting structures in a range of applications, we show how to create morphable structural materials using a neutrally stable unit cell as a building block. This unit cell is a self-stressed hinged structure…

Soft Condensed Matter · Physics 2021-10-18 Gaurav Chaudhary , S Ganga Prasath , Edward Soucy , L Mahadevan

Based on a group theoretical setting a sort of discrete dynamical system is constructed and applied to a combinatorial dynamical system defined on the set of certain Bethe ansatz related objects known as the rigged configurations. This…

Exactly Solvable and Integrable Systems · Physics 2010-04-01 Taichiro Takagi

All intelligence is collective intelligence, in the sense that it is made of parts which must align with respect to system-level goals. Understanding the dynamics which facilitate or limit navigation of problem spaces by aligned parts thus…

Statistical Mechanics · Physics 2026-05-18 Francesco Sacco , Dalton A R Sakthivadivel , Michael Levin

We are entering a new era in which software systems are becoming more and more complex and larger. So, the composition of such systems is becoming infeasible by manual means. To address this challenge, self-organising software models…

Formal Languages and Automata Theory · Computer Science 2025-08-27 Damian Arellanes

A phenomenological description for active bundles of polar filaments is presented. The activity of the bundle results from crosslinks, that induce relative displacements between the aligned filaments. Our generic description is based on…

Statistical Mechanics · Physics 2009-11-07 Karsten Kruse , Frank Julicher

Self-organisation is the spontaneous emergence of spatio-temporal structures and patterns from the interaction of smaller individual units. Examples are found across many scales in very different systems and scientific disciplines, from…

We explore the integration of representations from a Lie algebra to its algebraic group in positive characteristic. An integrable module is stable under the twists by group elements. Our aim is to investigate cohomological obstructions for…

Representation Theory · Mathematics 2019-10-30 Dmitriy Rumynin , Matthew Westaway

Here we provide a detailed analysis, along with some extensions and additonal investigations, of a recently proposed self-organised model for the evolution of complex networks. Vertices of the network are characterised by a fitness variable…

Physics and Society · Physics 2008-08-29 Guido Caldarelli , Andrea Capocci , Diego Garlaschelli

In this paper, we are concerned with studying the existence of invariant complex manifolds of two-dimensional holomorphic systems. From the geometric singular perturbation theory we know that if a slow-fast system has associated a normally…

Dynamical Systems · Mathematics 2023-04-04 Gabriel Rondón , Paulo R. da Silva , Luiz F. S. Gouveia

Secondary homological stability is a recently discovered stability pattern for the homology of a sequence of spaces exhibiting homological stability in a range where homological stability does not hold. We prove secondary homological…

Algebraic Topology · Mathematics 2023-07-04 Zachary Himes

This note aims at obtaining a variational characterization of complex structures by means of a calculus of variations for real vector bundle valued differential forms, and outlines a perspective to study existence questions via functionals…

Differential Geometry · Mathematics 2022-02-17 Gabriella Clemente

The article is devoted to microbundles over topological rings. Their structure, homomorphisms, automorphisms and extensions are studied. Moreover, compactifications and inverse spectra of microbundles over topological rings are…

General Topology · Mathematics 2019-03-29 Sergey V. Ludkovsky

We investigate a discrete model consisting of self-propelled particles that obey simple interaction rules. We show that this model can self-organize and exhibit coherent localized solutions in one- and in two-dimensions.In one-dimension,…

Soft Condensed Matter · Physics 2009-10-31 Herbert Levine , Wouter-Jan Rappel , Inon Cohen

All languages have a noun category, but its realisation varies considerably. Depending on the language, semantic and/or morphosyntactic differences may be more or less pronounced. This paper explores these variations, using Riffian as a…

Computation and Language · Computer Science 2026-04-07 Mohamed El Idrissi

It is proposed that self-organisation (SO) in non-equilibrium systems is governed by a general principle: it emerges when a minute subset of system configurations are exceptionally stable and long-lived to survive the noise generated by the…

Statistical Mechanics · Physics 2026-04-20 Raphael Blumenfeld

We investigate combinatorial dynamical systems on simplicial complexes considered as {\em finite topological spaces}. Such systems arise in a natural way from sampling dynamics and may be used to reconstruct some features of the dynamics…

Algebraic Topology · Mathematics 2018-07-12 Tamal K. Dey , Mateusz Juda , Tomasz Kapela , Jacek Kubica , Michal Lipinski , Marian Mrozek