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Precision medicine has become a central focus in breast cancer management, advancing beyond conventional methods to deliver more precise and individualized therapies. Traditionally, histopathology images have been used primarily for…

Quantitative Methods · Quantitative Biology 2024-12-17 Suchithra Kunhoth , Somaya Al- Maadeed , Younes Akbari , Rafif Al Saady

Purpose: Artificial intelligence (AI) solutions for medical diagnosis require thorough evaluation to demonstrate that performance is maintained for all patient sub-groups and to ensure that proposed improvements in care will be delivered…

Image and Video Processing · Electrical Eng. & Systems 2022-09-20 Tom Dyer , Jordan Smith , Gaetan Dissez , Nicole Tay , Qaiser Malik , Tom Naunton Morgan , Paul Williams , Liliana Garcia-Mondragon , George Pearse , Simon Rasalingham

Purpose: Most studies evaluating artificial intelligence (AI) models that detect abnormalities in neuroimaging are either tested on unrepresentative patient cohorts or are insufficiently well-validated, leading to poor generalisability to…

Image and Video Processing · Electrical Eng. & Systems 2024-05-10 Siddharth Agarwal , David A. Wood , Mariusz Grzeda , Chandhini Suresh , Munaib Din , James Cole , Marc Modat , Thomas C Booth

Designing Artificial Intelligence (AI) solutions that can operate in real-world situations is a highly complex task. Deploying such solutions in the medical domain is even more challenging. The promise of using AI to improve patient care…

Human-Computer Interaction · Computer Science 2021-10-08 Sagi Schein , Greg Arutiunian , Vitaly Burshtein , Gal Sadeh , Michelle Townshend , Bruce Friedman , Shada Sadr-azodi

Pathology image analysis plays a pivotal role in medical diagnosis, with deep learning techniques significantly advancing diagnostic accuracy and research. While numerous studies have been conducted to address specific pathological tasks,…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Dankai Liao , Sicheng Chen , Nuwa Xi , Qiaochu Xue , Jieyu Li , Lingxuan Hou , Zeyu Liu , Chang Han Low , Yufeng Wu , Yiling Liu , Yanqin Jiang , Dandan Li , Shangqing Lyu

Purpose: In this work, we present a collaboration to create a validation dataset of pathologist annotations for algorithms that process whole slide images (WSIs). We focus on data collection and evaluation of algorithm performance in the…

Grading precancerous lesions on whole slide images is a challenging task: the continuous space of morphological phenotypes makes clear-cut decisions between different grades often difficult, leading to low inter- and intra-rater agreements.…

Image and Video Processing · Electrical Eng. & Systems 2023-03-09 Mélanie Lubrano , Yaëlle Bellahsen-Harrar , Rutger Fick , Cécile Badoual , Thomas Walter

Artificial intelligence (AI) systems have the potential to revolutionize clinical practices, including improving diagnostic accuracy and surgical decision-making, while also reducing costs and manpower. However, it is important to recognize…

Artificial Intelligence · Computer Science 2024-09-18 Yifan Yang , Mingquan Lin , Han Zhao , Yifan Peng , Furong Huang , Zhiyong Lu

Histopathological images (HIs) are the gold standard for evaluating some types of tumors for cancer diagnosis. The analysis of such images is not only time and resource consuming, but also very challenging even for experienced pathologists,…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Jonathan de Matos , Steve Tsham Mpinda Ataky , Alceu de Souza Britto , Luiz Eduardo Soares de Oliveira , Alessandro Lameiras Koerich

Histopathological image analysis is the gold standard to diagnose cancer. Carcinoma is a subtype of cancer that constitutes more than 80% of all cancer cases. Squamous cell carcinoma and adenocarcinoma are two major subtypes of carcinoma,…

Image and Video Processing · Electrical Eng. & Systems 2022-01-20 Swathi Prabhua , Keerthana Prasada , Antonio Robels-Kelly , Xuequan Lu

Artificial intelligence (AI) is being deployed within radiology at a rapid pace. AI has proven an excellent tool for reconstructing and enhancing images that appear sharper, smoother, and more detailed, can be acquired more quickly, and…

Artificial Intelligence · Computer Science 2026-02-11 Jana G. Delfino , Jason L. Granstedt , Frank W. Samuelson , Robert Ochs , Krishna Juluru

Recent advancements in artificial intelligence (AI) have revolutionized cardiovascular medicine, particularly through integration with computed tomography (CT), magnetic resonance imaging (MRI), electrocardiography (ECG) and ultrasound…

Computer Vision and Pattern Recognition · Computer Science 2025-06-05 Yuanlin Mo , Haishan Huang , Bocheng Liang , Weibo Ma

Artificial intelligence (AI) systems increasingly match or surpass human experts in biomedical signal interpretation. However, their effective integration into clinical practice requires more than high predictive accuracy. Clinicians must…

Machine Learning · Computer Science 2025-10-27 Stefan Kraft , Andreas Theissler , Vera Wienhausen-Wilke , Gjergji Kasneci , Hendrik Lensch

Artificial intelligence (AI) holds great promise for supporting clinical trials, from patient recruitment and endpoint assessment to treatment response prediction. However, deploying AI without safeguards poses significant risks,…

Machine Learning · Computer Science 2025-10-09 Yao Chen , David Ohlssen , Aimee Readie , Gregory Ligozio , Ruvie Martin , Thibaud Coroller

Benchmarking competitions are central to the development of artificial intelligence (AI) in medical imaging, defining performance standards and shaping methodological progress. However, it remains unclear whether these benchmarks provide…

Artificial Intelligence (AI) is poised to transform healthcare delivery through revolutionary advances in clinical decision support and diagnostic capabilities. While human expertise remains foundational to medical practice, AI-powered…

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

Quality assurance is a critical but underexplored area in digital pathology, where even minor artifacts can have significant effects. Artifacts have been shown to negatively impact the performance of AI diagnostic models. In current…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Meredith VandeHaar , M. Clinch , I. Yilmaz , M. A. Rahman , Y. Xiao , F. Dogany , H. M. Alazab , A. Nassar , Z. Akkus , B. Dangott

Histopathological images contain abundant phenotypic information and pathological patterns, which are the gold standards for disease diagnosis and essential for the prediction of patient prognosis and treatment outcome. In recent years,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Linhao Qu , Siyu Liu , Xiaoyu Liu , Manning Wang , Zhijian Song

The increasing prevalence of retinal diseases poses a significant challenge to the healthcare system, as the demand for ophthalmologists surpasses the available workforce. This imbalance creates a bottleneck in diagnosis and treatment,…

Image and Video Processing · Electrical Eng. & Systems 2025-09-17 Jia-Hong Huang
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