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PET is affected by statistical noise due to constraints on tracer dose and scan duration, impacting both diagnostic performance and quantitative accuracy. While deep learning (DL)-based PET denoising methods have been used to improve image…

Recent work has shown that the structure of convolutional neural networks (CNNs) induces a strong prior that favors natural images. This prior, known as a deep image prior (DIP), is an effective regularizer in inverse problems such as image…

Computer Vision and Pattern Recognition · Computer Science 2020-12-03 Pallabi Ghosh , Vibhav Vineet , Larry S. Davis , Abhinav Shrivastava , Sudipta Sinha , Neel Joshi

Dynamic positron emission tomography (PET) images can reveal the distribution of tracers in the organism and the dynamic processes involved in biochemical reactions, and it is widely used in clinical practice. Despite the high effectiveness…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Jie Sun , Junyan Zhang , Qian Xia , Chuanfu Sun , Yumei Chen , Yunjie Yang , Huafeng Liu , Wentao Zhu , Qiegen Liu

Positron range (PR) blurring degrades positron emission tomography (PET) image resolution, particularly for high-energy emitters like gallium-68 (68 Ga). We introduce Dual-Input Dynamic Convolution (DDConv), a novel computationally…

Direct reconstruction of positron emission tomography (PET) data using deep neural networks is a growing field of research. Initial results are promising, but often the networks are complex, memory utilization inefficient, produce…

Image and Video Processing · Electrical Eng. & Systems 2020-06-16 William Whiteley , Vladimir Panin , Chuanyu Zhou , Jorge Cabello , Deepak Bharkhada , Jens Gregor

Low-dose CT (LDCT) imaging is desirable in many clinical applications to reduce X-ray radiation dose to patients. Inspired by deep learning (DL), a recent promising direction of model-based iterative reconstruction (MBIR) methods for LDCT…

Image and Video Processing · Electrical Eng. & Systems 2021-02-18 Qiaoqiao Ding , Yuesong Nan , Hao Gao , Hui Ji

Deep learning based PET image reconstruction methods have achieved promising results recently. However, most of these methods follow a supervised learning paradigm, which rely heavily on the availability of high-quality training labels. In…

Image and Video Processing · Electrical Eng. & Systems 2023-03-13 Rui Hu , Yunmei Chen , Kyungsang Kim , Marcio Aloisio Bezerra Cavalcanti Rockenbach , Quanzheng Li , Huafeng Liu

In this paper, we explore a novel method for tomographic image reconstruction in the field of SPECT imaging. Deep Learning methodologies and more specifically deep convolutional neural networks (CNN) are employed in the new reconstruction…

Machine Learning · Computer Science 2020-10-20 Charalambos Chrysostomou , Loizos Koutsantonis , Christos Lemesios , Costas N. Papanicolas

Purpose: Neural network image reconstruction directly from measurement data is a relatively new field of research, that until now has been limited to producing small single-slice images (e.g., 1x128x128). This paper proposes a novel and…

Image and Video Processing · Electrical Eng. & Systems 2020-02-13 William Whiteley , Wing K. Luk , Jens Gregor

Patient motion during PET is inevitable. Its long acquisition time not only increases the motion and the associated artifacts but also the patient's discomfort, thus PET acceleration is desirable. However, accelerating PET acquisition will…

Image and Video Processing · Electrical Eng. & Systems 2023-02-15 Bo Zhou , Yu-Jung Tsai , Jiazhen Zhang , Xueqi Guo , Huidong Xie , Xiongchao Chen , Tianshun Miao , Yihuan Lu , James S. Duncan , Chi Liu

In SPECT image reconstruction, limited-angle (LA) conditions lead to a loss of frequency components, which distort the reconstructed tomographic image along directions corresponding to the non-collected projection angle range. Although…

Medical Physics · Physics 2025-07-16 Kensuke Hori , Fumio Hashimoto , Kazuya Koyama , Takeyuki Hashimoto

Commercial iterative reconstruction techniques on modern CT scanners target radiation dose reduction but there are lingering concerns over their impact on image appearance and low contrast detectability. Recently, machine learning,…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Hongming Shan , Atul Padole , Fatemeh Homayounieh , Uwe Kruger , Ruhani Doda Khera , Chayanin Nitiwarangkul , Mannudeep K. Kalra , Ge Wang

Positron emission tomography(PET) image reconstruction is an ill-posed inverse problem and suffers from high level of noise due to limited counts received. Recently deep neural networks especially convolutional neural networks(CNN) have…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Rui Hu , Huafeng Liu

Positron emission tomography (PET) suffers from severe resolution limitations which limit its quantitative accuracy. In this paper, we present a super-resolution (SR) imaging technique for PET based on convolutional neural networks (CNNs).…

Image and Video Processing · Electrical Eng. & Systems 2021-07-29 Tzu-An Song , Samadrita Roy Chowdhury , Fan Yang , Joyita Dutta

Ill-posed inverse problems appear in many image processing applications, such as deblurring and super-resolution. In recent years, solutions that are based on deep Convolutional Neural Networks (CNNs) have shown great promise. Yet, most of…

Computer Vision and Pattern Recognition · Computer Science 2021-02-05 Shady Abu-Hussein , Tom Tirer , Se Young Chun , Yonina C. Eldar , Raja Giryes

Time-of-flight (TOF) information provides more accurate location data for annihilation photons, thereby enhancing the quality of PET reconstruction images and reducing noise. List-mode reconstruction has a significant advantage in handling…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Rui Hu , Chenxu Li , Kun Tian , Jianan Cui , Yunmei Chen , Huafeng Liu

Positron Emission Tomography (PET) image reconstruction is inherently challenged by Poisson noise and physical degradation factors, which are further exacerbated in limited-angle acquisitions. While deep learning methods demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Rüveyda Yilmaz , Yuli Wu , Johannes Stegmaier , Volkmar Schulz

We present a tomographic imaging technique, termed Deep Prior Diffraction Tomography (DP-DT), to reconstruct the 3D refractive index (RI) of thick biological samples at high resolution from a sequence of low-resolution images collected…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Kevin C. Zhou , Roarke Horstmeyer

Combining dual-energy computed tomography (DECT) with positron emission tomography (PET) offers many potential clinical applications but typically requires expensive hardware upgrades or increases radiation doses on PET/CT scanners due to…

Medical Physics · Physics 2024-06-21 Siqi Li , Yansong Zhu , Benjamin A. Spencer , Guobao Wang

Low-Dose computer tomography (LDCT) is an ideal alternative to reduce radiation risk in clinical applications. Although supervised-deep-learning-based reconstruction methods have demonstrated superior performance compared to conventional…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Feng Wang , Renfang Wang , Hong Qiu