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Age-related macular degeneration (AMD) is the leading cause of visual impairment among elderly in the world. Early detection of AMD is of great importance, as the vision loss caused by this disease is irreversible and permanent. Color…

The ultra-wide optical coherence tomography angiography (OCTA) has become an important imaging modality in diabetic retinopathy (DR) diagnosis. However, there are few researches focusing on automatic DR analysis using ultra-wide OCTA. In…

Image and Video Processing · Electrical Eng. & Systems 2022-10-04 Junlin Hou , Fan Xiao , Jilan Xu , Yuejie Zhang , Haidong Zou , Rui Feng

Optical Coherence Tomography (OCT) is essential for diagnosing conditions such as glaucoma, diabetic retinopathy, and age-related macular degeneration. Accurate retinal layer segmentation enables quantitative biomarkers critical for…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 S M Asiful Islam Saky , Ugyen Tshering

We present an unsupervised deep neural network approach to the fusion of RGB-D imagery with inertial measurements for absolute trajectory estimation. Our network, dubbed the Visual-Inertial-Odometry Learner (VIOLearner), learns to perform…

Computer Vision and Pattern Recognition · Computer Science 2018-03-16 E. Jared Shamwell , Sarah Leung , William D. Nothwang

Approximately 200 million individuals around the world suffer from varying degrees of visual impairment, making it crucial to leverage AI technology to offer walking assistance for these people. With the recent progress of vision-language…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Zhiqiang Yuan , Ting Zhang , Ying Deng , Jiapei Zhang , Yeshuang Zhu , Zexi Jia , Jie Zhou , Jinchao Zhang

Interpretability is crucial to enhance trust in machine learning models for medical diagnostics. However, most state-of-the-art image classifiers based on neural networks are not interpretable. As a result, clinicians often resort to known…

Accurate and robust localization is a fundamental need for mobile agents. Visual-inertial odometry (VIO) algorithms exploit the information from camera and inertial sensors to estimate position and translation. Recent deep learning based…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Zheming Tu , Changhao Chen , Xianfei Pan , Ruochen Liu , Jiarui Cui , Jun Mao

Vision-Language Models (VLMs) offer a promising path toward interpretable medical diagnosis by allowing users to ask about clinical explanations alongside predictions and across different modalities. However, training VLMs for detailed…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Chenjun Li , Cheng Wan , Laurin Lux , Alexander Berger , Richard B. Rosen , Martin J. Menten , Johannes C. Paetzold

The segmentation and analysis of coronary arteries from intravascular optical coherence tomography (IVOCT) is an important aspect of diagnosing and managing coronary artery disease. Current image processing methods are hindered by the time…

Machine Learning · Computer Science 2021-04-20 Arjun Balaji , Lachlan Kelsey , Kamran Majeed , Carl Schultz , Barry Doyle

In this paper, we propose a framework that incorporates experts diagnostics and insights into the analysis of Optical Coherence Tomography (OCT) using multi-modal learning. To demonstrate the effectiveness of this approach, we create a…

Image and Video Processing · Electrical Eng. & Systems 2022-03-22 Y. Logan , K. Kokilepersaud , G. Kwon , G. AlRegib , C. Wykoff , H. Yu

Vision-and-language multi-modal pretraining and fine-tuning have shown great success in visual question answering (VQA). Compared to general domain VQA, the performance of biomedical VQA suffers from limited data. In this paper, we propose…

Computer Vision and Pattern Recognition · Computer Science 2023-03-02 Zheng Yuan , Qiao Jin , Chuanqi Tan , Zhengyun Zhao , Hongyi Yuan , Fei Huang , Songfang Huang

Clinicians spend a significant amount of time reviewing medical images and transcribing their findings regarding patient diagnosis, referral and treatment in text form. Vision-language models (VLMs), which automatically interpret images and…

Purpose: To create and evaluate the accuracy of an artificial intelligence Deep learning platform (ORAiCLE) capable of using only retinal fundus images to predict both an individuals overall 5 year cardiovascular risk (CVD) and the relative…

Image and Video Processing · Electrical Eng. & Systems 2022-08-26 Ehsan Vaghefi , David Squirrell , Songyang An , Song Yang , John Marshall

Geographic atrophy (GA) is a key biomarker of dry age-related macular degeneration (AMD) traditionally identified through color fundus photography. Hyper-transmission defects (hyperTDs), a feature highly correlated with GA, have recently…

Quantitative Methods · Quantitative Biology 2025-11-04 Yukun Guo , An-Lun Wu , Tristan T. Hormel , Liqin Gao , Min Gao , Thomas S. Hwang , Steven T. Bailey , Yali Jia

Recent studies suggest that early stages of diabetic retinopathy (DR) can be diagnosed by monitoring vascular changes in the deep vascular complex. In this work, we investigate a novel method for automated DR grading based on optical…

Image and Video Processing · Electrical Eng. & Systems 2022-12-22 Linus Kreitner , Ivan Ezhov , Daniel Rueckert , Johannes C. Paetzold , Martin J. Menten

Optical coherence tomography (OCT) is one of the non-invasive and easy-to-acquire biomarkers (the thickness of the retinal layers, which is detectable within OCT scans) being investigated to diagnose Alzheimer's disease (AD). This work aims…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Paria Jeihouni , Omid Dehzangi , Annahita Amireskandari , Ali Dabouei , Ali Rezai , Nasser M. Nasrabadi

Purpose: To validate the performance of a commercially-available, CE-certified deep learning (DL) system, RetCAD v.1.3.0 (Thirona, Nijmegen, The Netherlands), for the joint automatic detection of diabetic retinopathy (DR) and age-related…

Automatic evaluation of the retinal fundus image is emerging as one of the most important tools for early detection and treatment of progressive eye diseases like Glaucoma. Glaucoma results to a progressive degeneration of vision and is…

Image and Video Processing · Electrical Eng. & Systems 2021-12-13 Sneha Dasgupta , Rishav Mukherjee , Kaushik Dutta , Anindya Sen

Visual Inertial Odometry (VIO) is the task of estimating the movement trajectory of an agent from an onboard camera stream fused with additional Inertial Measurement Unit (IMU) measurements. A crucial subtask within VIO is the tracking of…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 Jonas Kühne , Michele Magno , Luca Benini

Chart-based visual acuity measurements are used by billions of people to diagnose and guide treatment of vision impairment. However, the ubiquitous eye exam has no mechanism for reasoning about uncertainty and as such, suffers from a…

Artificial Intelligence · Computer Science 2019-11-25 Chris Piech , Ali Malik , Laura M Scott , Robert T Chang , Charles Lin