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Uncertainty quantification is an important prerequisite for the deployment of deep learning models in safety-critical areas. Yet, this hinges on the uncertainty estimates being useful to the extent the prediction intervals are…

Machine Learning · Computer Science 2025-07-29 Dharmesh Tailor , Alvaro H. C. Correia , Eric Nalisnick , Christos Louizos

Motivated by data-rich experiments in transcriptional regulation and sensory neuroscience, we consider the following general problem in statistical inference. When exposed to a high-dimensional signal S, a system of interest computes a…

Quantitative Methods · Quantitative Biology 2013-12-16 Justin B. Kinney , Gurinder S. Atwal

High-resolution functional imaging is providing increasingly rich measurements of brain activity in animals and humans. A major challenge is to leverage such data to gain insight into the brain's computational mechanisms. The first step is…

Neurons and Cognition · Quantitative Biology 2016-08-09 Nikolaus Kriegeskorte , Jörn Diedrichsen

Bayesian nonparametric methods are a popular choice for analysing survival data due to their ability to flexibly model the distribution of survival times. These methods typically employ a nonparametric prior on the survival function that is…

Methodology · Statistics 2022-02-22 Edwin Fong , Brieuc Lehmann

Wide-field imaging Mueller polarimetry is a revolutionary, label-free, and non-invasive modality for computer-aided intervention: in neurosurgery it aims to provide visual feedback of white matter fibre bundle orientation from derived…

In survival analysis, the estimation of the proportion of subjects who will never experience the event of interest, termed the cure rate, has received considerable attention recently. Its estimation can be a particularly difficult task when…

Statistics Theory · Mathematics 2025-04-02 Jan Beirlant , Martin Bladt , Ingrid Van Keilegom

Selecting relevant features associated with a given response variable is an important issue in many scientific fields. Quantifying quality and uncertainty of a selection result via false discovery rate (FDR) control has been of recent…

Methodology · Statistics 2020-12-17 Chenguang Dai , Buyu Lin , Xin Xing , Jun S. Liu

We introduce inherent measures for effective quality control of brain segmentation based on a Bayesian fully convolutional neural network, using model uncertainty. Monte Carlo samples from the posterior distribution are efficiently…

Computer Vision and Pattern Recognition · Computer Science 2018-06-11 Abhijit Guha Roy , Sailesh Conjeti , Nassir Navab , Christian Wachinger

Recent reports of inflated false positive rates (FPRs) in FMRI group analysis tools by Eklund et al. (2016) have become a large topic within (and outside) neuroimaging. They concluded that: existing parametric methods for determining…

Quantitative Methods · Quantitative Biology 2017-02-17 Robert W. Cox , Gang Chen , Daniel R. Glen , Richard C. Reynolds , Paul A. Taylor

Recent cost volume pyramid based deep neural networks have unlocked the potential of efficiently leveraging high-resolution images for depth inference from multi-view stereo. In general, those approaches assume that the depth of each pixel…

Computer Vision and Pattern Recognition · Computer Science 2022-05-10 Jiayu Yang , Jose M. Alvarez , Miaomiao Liu

I introduce a generic method for inference on entire quantile and regression quantile processes in the presence of a finite number of large and arbitrarily heterogeneous clusters. The method asymptotically controls size by generating…

Econometrics · Economics 2023-06-16 Andreas Hagemann

New experimental methods make it possible to measure the expression levels of many genes, simultaneously, in snapshots from thousands or even millions of individual cells. Current approaches to analyze these experiments involve clustering…

Traditional voxel-level multiple testing procedures in neuroimaging, mostly $p$-value based, often ignore the spatial correlations among neighboring voxels and thus suffer from substantial loss of power. We extend the…

Applications · Statistics 2016-07-29 Hai Shu , Bin Nan , Robert Koeppe

A new depth-based clustering procedure for directional data is proposed. Such method is fully non-parametric and has the advantages to be flexible and applicable even in high dimensions when a suitable notion of depth is adopted. The…

Methodology · Statistics 2022-06-22 Giuseppe Pandolfo , Antonio D'ambrosio

The goal of this paper is to provide some tools for nonparametric estimation and inference in psychological and economic experiments. We consider an experimental framework in which each of $n$subjects provides $T$ responses to a vector of…

Econometrics · Economics 2019-12-10 Raffaello Seri , Samuele Centorrino , Michele Bernasconi

Concept-selective regions within the human cerebral cortex exhibit significant activation in response to specific visual stimuli associated with particular concepts. Precisely localizing these regions stands as a crucial long-term goal in…

Neurons and Cognition · Quantitative Biology 2025-03-05 Guangyin Bao , Qi Zhang , Zixuan Gong , Zhuojia Wu , Duoqian Miao

There are a number of ways to test for the absence/presence of a spatial signal in a completely observed fine-resolution image. One of these is a powerful nonparametric procedure called Enhanced False Discovery Rate (EFDR). A drawback of…

Methodology · Statistics 2020-10-20 Hsin-Cheng Huang , Noel Cressie , Andrew Zammit-Mangion , Guowen Huang

Controlling the False Discovery Rate (FDR) in a variable selection procedure is critical for reproducible discoveries, and it has been extensively studied in sparse linear models. However, it remains largely open in scenarios where the…

Methodology · Statistics 2023-11-16 Yang Cao , Xinwei Sun , Yuan Yao

Threshold-free cluster enhancement (TFCE) integrates cluster extent across thresholds to improve voxel-wise neuroimaging inference, but permutation testing makes it prohibitively slow for large datasets. Probabilistic TFCE (pTFCE) uses…

Image and Video Processing · Electrical Eng. & Systems 2026-05-08 Don Yin , Hao Chen , Takeshi Miki , Enyu Yang

Neural simulation-based inference is a powerful class of machine-learning-based methods for statistical inference that naturally handles high-dimensional parameter estimation without the need to bin data into low-dimensional summary…

Data Analysis, Statistics and Probability · Physics 2025-06-16 ATLAS Collaboration