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We propose a noninvasive and dispersive framework for estimating the spatially nonuniform conductivity of brain tumors using MR images. The method consists of two components: (i) voxel-wise assignment of tumor conductivity based on…

Medical Physics · Physics 2025-09-19 Yoshiki Kubota , Yosuke Nagata , Manabu Tamura , Akimasa Hirata

Novel Categories Discovery (NCD) aims to cluster novel data based on the class semantics of known classes using the open-world partial class space annotated dataset. As an alternative to the traditional pseudo-labeling-based approaches, we…

Computer Vision and Pattern Recognition · Computer Science 2023-12-19 Zahid Hasan , Abu Zaher Md Faridee , Masud Ahmed , Sanjay Purushotham , Heesung Kwon , Hyungtae Lee , Nirmalya Roy

We develop novel clustering algorithms for functional data when the number of clusters $K$ is unknown and also when it is prefixed. These algorithms are developed based on the Maximum Mean Discrepancy (MMD) measure between two sets of…

Methodology · Statistics 2025-07-16 Sourav Chakrabarty , Anirvan Chakraborty , Shyamal K. De

The validity of two-step or plug-in inference methods is questioned in the Bayesian framework. We study semi-parametric models where the plug-in of a non-parametrically modelled nuisance component is used. We show that when the nuisance and…

Statistics Theory · Mathematics 2026-02-25 Magid Sabbagh , David A. Stephens

Multiple hypothesis testing is a fundamental problem in high dimensional inference, with wide applications in many scientific fields. In genome-wide association studies, tens of thousands of tests are performed simultaneously to find if any…

Methodology · Statistics 2011-11-16 Jianqing Fan , Xu Han , Weijie Gu

Many applications of classification methods not only require high accuracy but also reliable estimation of predictive uncertainty. However, while many current classification frameworks, in particular deep neural networks, achieve high…

Machine Learning · Computer Science 2020-02-28 Jonathan Wenger , Hedvig Kjellström , Rudolph Triebel

Multiple comparison procedures that control a family-wise error rate or false discovery rate provide an achieved error rate as the adjusted p-value for each hypothesis tested. However, since such p-values are not probabilities that the null…

Methodology · Statistics 2013-09-03 David R. Bickel

With recent advances in deep learning, neuroimaging studies increasingly rely on convolutional networks (ConvNets) to predict diagnosis based on MR images. To gain a better understanding of how a disease impacts the brain, the studies…

Machine Learning · Computer Science 2021-06-29 Qingyu Zhao , Ehsan Adeli , Adolf Pfefferbaum , Edith V. Sullivan , Kilian M. Pohl

In large scale multiple testing, the use of an empirical null distribution rather than the theoretical null distribution can be critical for correct inference. This paper proposes a ``mode matching'' method for fitting an empirical null…

Applications · Statistics 2009-01-27 Armin Schwartzman

Lesion-symptom mapping studies provide insight into what areas of the brain are involved in different aspects of cognition. This is commonly done via behavioral testing in patients with a naturally occurring brain injury or lesions (e.g.,…

In this paper, we aim to estimate the direction of an underlying signal from its nonlinear observations following the semi-parametric single index model (SIM). Unlike conventional compressed sensing where the signal is assumed to be sparse,…

Machine Learning · Computer Science 2022-06-02 Jiulong Liu , Zhaoqiang Liu

Given a limited labeling budget, active learning (AL) aims to sample the most informative instances from an unlabeled pool to acquire labels for subsequent model training. To achieve this, AL typically measures the informativeness of…

Machine Learning · Computer Science 2023-07-07 Cheng Chen , Yong Wang , Lizi Liao , Yueguo Chen , Xiaoyong Du

This paper considers the problem of inference in cluster randomized experiments when cluster sizes are non-ignorable. Here, by a cluster randomized experiment, we mean one in which treatment is assigned at the cluster level. By…

Econometrics · Economics 2024-04-11 Federico Bugni , Ivan Canay , Azeem Shaikh , Max Tabord-Meehan

Large-scale hypothesis testing is central to modern science, where controlling the False Discovery Rate (FDR) has become the standard approach to managing false positives across many simultaneous tests. Hypotheses rarely exist in isolation;…

Methodology · Statistics 2026-05-19 Binyamin Perets , Shie Mannor

Identifying areas where the signal is prominent is an important task in image analysis, with particular applications in brain mapping. In this work, we develop confidence regions for spatial excursion sets above and below a given level. We…

Methodology · Statistics 2025-04-18 Howon Ryu , Thomas Maullin-Sapey , Armin Schwartzman , Samuel Davenport

Community detection is a fundamental unsupervised learning problem for unlabeled networks which has a broad range of applications. Many community detection algorithms assume that the number of clusters $r$ is known apriori. In this paper,…

Machine Learning · Statistics 2018-03-20 Bowei Yan , Purnamrita Sarkar , Xiuyuan Cheng

Identification of clusters of co-expressed genes in transcriptomic data is a difficult task. Most algorithms used for this purpose can be classified into two broad categories: distance-based or model-based approaches. Distance-based…

Applications · Statistics 2022-09-26 Gabriel Lozano , Nadia Atallah , Michael Levine

Nonresponse frequently arises in practice, and simply ignoring it may lead to erroneous inference. Besides, the number of collected covariates may increase as the sample size in modern statistics, so parametric imputation or propensity…

Methodology · Statistics 2022-09-29 Xin He , Xiaojun Mao , Zhonglei Wang

Change point analysis has applications in a wide variety of fields. The general problem concerns the inference of a change in distribution for a set of time-ordered observations. Sequential detection is an online version in which new data…

Methodology · Statistics 2013-10-16 David S. Matteson , Nicholas A. James

Clustering is a common task in machine learning, but clusters of unlabelled data can be hard to quantify. The application of clustering algorithms in chemistry is often dependant on material representation. Ascertaining the effects of…

Machine Learning · Computer Science 2023-05-29 Samantha Durdy , Michael W. Gaultois , Vladimir Gusev , Danushka Bollegala , Matthew J. Rosseinsky
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