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Related papers: Notip: Non-parametric True Discovery Proportion co…

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All Resolutions Inference (ARI) is a post hoc inference method for functional Magnetic Resonance Imaging (fMRI) data analysis that provides valid lower bounds on the proportion of truly active voxels within any, possibly data-driven,…

Statistics Theory · Mathematics 2025-11-05 Nils Peyrouset , Pierre Neuvial , Bertrand Thirion

Two permutation-based methods for simultaneous inference on the proportion of active voxels in cluster-wise brain imaging analysis have recently been published: Notip (Blain et al. 2022) and pARI (Andreella et al. 2023). Both rely on the…

Applications · Statistics 2024-02-07 Angela Andreella , Anna Vesely , Weeda Wouter , Jelle Goeman

Cluster inference based on spatial extent thresholding is the most popular analysis method for finding activated brain areas in neuroimaging. However, the method has several well-known issues. While powerful for finding brain regions with…

Methodology · Statistics 2022-08-10 Jelle J. Goeman , Paweł\ Górecki , Ramin Monajemi , Xu Chen , Thomas E. Nichols , Wouter Weeda

Classical cluster inference is hampered by the spatial specificity paradox. Given the null-hypothesis of no active voxels, the alternative hypothesis states that there is at least one active voxel in a cluster. Hence, the larger the cluster…

Methodology · Statistics 2023-05-12 Xu Chen , Jelle J. Goeman , Thijmen J. P. Krebs , Rosa J. Meijer , Wouter D. Weeda

We propose a permutation-based method for testing a large collection of hypotheses simultaneously. Our method provides lower bounds for the number of true discoveries in any selected subset of hypotheses. These bounds are simultaneously…

Applications · Statistics 2023-01-30 Angela Andreella , Jesse Hemerik , Wouter Weeda , Livio Finos , Jelle Goeman

Functional magnetic resonance imaging (fMRI) aims to locate activated regions in human brains when specific tasks are performed. The conventional tool for analyzing fMRI data applies some variant of the linear model, which is restrictive in…

Statistics Theory · Mathematics 2008-08-08 Chunming Zhang , Tao Yu

The most widely used task fMRI analyses use parametric methods that depend on a variety of assumptions. While individual aspects of these fMRI models have been evaluated, they have not been evaluated in a comprehensive manner with empirical…

Applications · Statistics 2016-07-14 Anders Eklund , Thomas Nichols , Hans Knutsson

Controlled variable selection is an important analytical step in various scientific fields, such as brain imaging or genomics. In these high-dimensional data settings, considering too many variables leads to poor models and high costs,…

Methodology · Statistics 2023-10-17 Alexandre Blain , Bertrand Thirion , Olivier Grisel , Pierre Neuvial

Voxel-based multiple testing is widely used in neuroimaging data analysis. Traditional false discovery rate (FDR) control methods often ignore the spatial dependence among the voxel-based tests and thus suffer from substantial loss of…

Machine Learning · Statistics 2024-05-06 Taehyo Kim , Hai Shu , Qiran Jia , Mony J. de Leon

We propose a method that combines signals from many brain regions observed in functional Magnetic Resonance Imaging (fMRI) to predict the subject's behavior during a scanning session. Such predictions suffer from the huge number of brain…

Computer Vision and Pattern Recognition · Computer Science 2011-04-29 Vincent Michel , Alexandre Gramfort , Gaël Varoquaux , Evelyn Eger , Christine Keribin , Bertrand Thirion

Variational methods are widely used for approximate posterior inference. However, their use is typically limited to families of distributions that enjoy particular conjugacy properties. To circumvent this limitation, we propose a family of…

Machine Learning · Computer Science 2012-06-22 Samuel Gershman , Matt Hoffman , David Blei

In this work we perform a meta-analysis of neuroimaging data, consisting of locations of peak activations identified in 162 separate studies on emotion. Neuroimaging meta-analyses are typically performed using kernel-based methods. However,…

Applications · Statistics 2012-06-29 Yu Ryan Yue , Martin A. Lindquist , Ji Meng Loh

Semi-supervised clustering is the task of clustering data points into clusters where only a fraction of the points are labelled. The true number of clusters in the data is often unknown and most models require this parameter as an input.…

Machine Learning · Computer Science 2013-09-27 Amar Shah , Zoubin Ghahramani

Voxel-based lesion-symptom mapping (VLSM) is a major method for studying brain-behavior relationships that leverages modern neuroimaging analysis techniques to build on the classic approach of examining the relationship between location of…

Applications · Statistics 2016-06-03 Daniel Mirman , Jon-Frederick Landrigan , Spiro Kokolis , Sean Verillo , Casey Ferrara

Threshold-free cluster enhancement (TFCE) is widely used for cluster-based inference in neuroimaging, but existing implementations typically rely on discretized approximations that may introduce numerical variability. We present eTFCE, an…

Methodology · Statistics 2026-04-28 Xu Chen , Wouter D. Weeda , Thomas E. Nichols , Jelle J. Goeman

False discovery rate (FDR) control methods are essential for voxel-wise multiple testing in neuroimaging data analysis, where hundreds of thousands or even millions of tests are conducted to detect brain regions associated with…

Machine Learning · Statistics 2025-05-30 Taehyo Kim , Qiran Jia , Mony J. de Leon , Hai Shu

In this paper, a noisy version of the stochastic block model (NSBM) is introduced and we investigate the three following statistical inferences in this model: estimation of the model parameters, clustering of the nodes and identification of…

Statistics Theory · Mathematics 2019-07-25 Tabea Rebafka , Etienne Roquain , Fanny Villers

It is frequently of interest to jointly analyze multiple sequences of multiple tests in order to identify simultaneous signals, defined as features tested in multiple studies whose test statistics are non-null in each. In many problems,…

Methodology · Statistics 2019-01-16 Sihai Dave Zhao , Yet Tien Nguyen

Functional MRI (fMRI) has become the most common method for investigating the human brain. However, fMRI data present some complications for statistical analysis and modeling. One recently developed approach to these data focuses on…

Applications · Statistics 2015-03-19 Vincent Q. Vu , Pradeep Ravikumar , Thomas Naselaris , Kendrick N. Kay , Jack L. Gallant , Bin Yu

Cluster analysis is an unsupervised learning strategy that can be employed to identify subgroups of observations in data sets of unknown structure. This strategy is particularly useful for analyzing high-dimensional data such as microarray…

Methodology · Statistics 2016-10-07 Erika S. Helgeson , Eric Bair
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